Results 21 to 30 of about 13,370 (136)

Serum B12, homocysteine levels, and their effect on peripheral neuropathy in Parkinson's disease: Indian cohort

Annals of Indian Academy of Neurology, 2020
Background: Cobalamin deficiency, either due to dietary inadequacy or increased consumption attributable to levodopa-mediated metabolic disturbance, and resultant hyperhomocysteinemia may contribute to peripheral neuropathy (PN) in Parkinson's disease ...
Neeharika L Mathukumalli, Mridula R Kandadai, Jabeen A Shaik, Meena A Kanikannan, Rupam Borgohain   +4 more
doaj   +1 more source

Elevated homocysteine activates unfolded protein responses and causes aberrant trophoblast differentiation and mouse blastocyst development

Physiological Reports, 2022
Hyperhomocysteinemia may arise from folate/vitamin B12 deficiency, genetic polymorphisms, kidney disease, or hypothyroidism. It is associated with an increased risk of early pregnancy loss and placenta‐related complications of pregnancy, including pre ...
Nadejda Capatina, Graham J. Burton, Hong Wa Yung   +2 more
doaj   +1 more source

Relationship between hyperhomocysteinemia and the risk of stroke recurrence:a Meta⁃analysis

Huli yanjiu, 2020
ObjectiveTo explore the relationship between hyperhomocysteinemia and the risk of stroke recurrence，so as to provide the basis for related clinical decision⁃making.MethodsThe prospective cohort studies on the relationship between hyperhomocysteinemia and
LIAO Qin, GAO Jing, ZHU Lin, CHEN Shi, ZHONG Yizhu, JIANG Xiaolin, ZHENG Yuping, WU Qiao   +7 more
doaj  

Homocysteine, vitamin B12 and folate levels in premature coronary artery disease

BMC Cardiovascular Disorders, 2006
Background Hyperhomocysteinemia is known as an independent risk factor of atherosclerosis, but the probable role of hyperhomocysteinemia in premature Coronary Artery Disease (CAD) is not well studied.
Fallah Nader, Mahmoodian Mehran, Davoodi Gholamreza, Salarifar Mojtaba, Fallahi Faramarz, Sadeghian Saeed, Darvish Soodabeh, Karimi Abbasali   +7 more
doaj   +1 more source

Inhibiting MARSs reduces hyperhomocysteinemia‐associated neural tube and congenital heart defects

EMBO Molecular Medicine, 2020
Hyperhomocysteinemia is a common metabolic disorder that imposes major adverse health consequences. Reducing homocysteine levels, however, is not always effective against hyperhomocysteinemia‐associated pathologies.
Xinyu Mei, Dashi Qi, Ting Zhang, Ying Zhao, Li Jin, Junli Hou, Jianhua Wang, Yan Lin, Yu Xue, Pingping Zhu, Zexian Liu, Lei Huang, Ji Nie, Wen Si, Jingyi Ma, Jianhong Ye, Richard H Finnell, Hexige Saiyin, Hongyan Wang, Jianyuan Zhao, Shimin Zhao, Wei Xu   +21 more
doaj   +1 more source

Higher gastric parietal cell antibody titer significantly increases the frequencies of macrocytosis, serum vitamin B12 deficiency, and hyperhomocysteinemia in patients with burning mouth syndrome

Journal of Dental Sciences, 2022
Background/purpose: Our previous study found 109 gastric parietal cell antibody (GPCA)-positive burning mouth syndrome (BMS) patients (so-called GPCA+BMS patients in this study) in a group of 884 BMS patients.
Ying-Tai Jin, Yu-Hsueh Wu, Yang-Che Wu, Julia Yu-Fong Chang, Chun-Pin Chiang, Andy Sun   +5 more
doaj   +1 more source

Hyperhomocysteinemia and Vitamin B Deficiency as Potential Aggravating Factors in Huntington's Disease: A Prospective Monocentric Study

Movement Disorders, EarlyView.
Abstract Background Although not confirmed, some studies have suggested that elevated homocysteine levels are common in patients with Huntington's disease (HD). Its clinical relevance remains unclear. Objectives We aimed to assess vitamin B and homocysteine levels in HD patients and explore the relationships among hyperhomocysteinemia, vitamin B ...
Salomé Puisieux, Elise Pourié, Céline Bonnet, Lucie Hopes, Solène Frismand, Myriam Bronner, Virginie Roth, Marion Wandzel, Natacha Sloboda, Laetitia Lambert, Abderrahim Oussalah, Amélia Julien, Irina Rotaru, Rosa‐Maria Guéant‐Rodriguez, Jean Louis Guéant, Carine Bossenmeyer‐Pourié, Mathilde Renaud   +16 more
wiley   +1 more source

Influence of Vitamin B12 Deficiency on Auditory and Vestibular Functioning: An Objective Test‐Based Systematic Review

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective To evaluate the effectiveness of objective audiological and vestibular assessments in detecting functional changes associated with vitamin B12 deficiency. Data Sources A comprehensive literature search was conducted in PubMed, Scopus, Web of Science, and EMBASE databases.
Nesmah Zainab, Santhosh Periyasamy, Kishan Madikeri Mohan   +2 more
wiley   +1 more source

Susceptibility to preoperative seizures in glioma patients with elevated homocysteine levels

Epilepsia Open, 2023
Objective Seizures are a common clinical presentation in patients with glioma and substantially impact patients' quality of life. Hyperhomocysteinemia is defined as abnormally high serum levels of homocysteine (Hcy) and is reportedly linked to ...
Xiaohan Chi, Jingjing Lu, Zhengguang Guo, Junmei Wang, Gaifen Liu, Zeping Jin, Yi Wang, Qianhe Zhang, Tai Sun, Nan Ji, Yang Zhang   +10 more
doaj   +1 more source

Protective Potentials of Natural Products Against Vascular Dementia: A Comprehensive Review of Experimental Studies

Phytotherapy Research, EarlyView.
ABSTRACT Vascular dementia (VaD), accounting for up to 20% of dementia cases globally, is primarily driven by chronic cerebral hypoperfusion (CCH), which leads to progressive cognitive impairment. Despite the increasing prevalence of VaD, effective treatments remain limited.
Jung‐Hoon Kim, Yongtaek Oh, Suin Cho
wiley   +1 more source