Results 231 to 240 of about 31,250 (276)
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Hyperhomocysteinemia and thrombophilia
Clinical Chemistry and Laboratory Medicine, 2010It is now widely accepted that hyperhomocysteinemia (HHC) is a risk factor for thrombophilia. HHC is the result of either impaired enzyme function or a deficiency of vitamin B (folate, B₆, B₁₂), or both, and can be treated with vitamin supplements.
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Diabetes Mellitus and Hyperhomocysteinemia
Seminars in Vascular Medicine, 2002Patients with diabetes mellitus are prone to cardiovascular disease and risk factors presumably unrelated to diabetes, such as hyperhomocysteinemia, may be involved in the atherothrombotic process in these subjects. Plasma homocysteine levels are usually normal in diabetes, although both lower and higher levels have been reported.
Coen, van Guldener, Coen D A, Stehouwer
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Hyperhomocysteinemia and Venous Thrombosis
Seminars in Hematology, 2007It has been recognized, since the first description of the disease, that arterial and venous thrombosis are common in patients with homocysteinuria. Interest in the condition increased with reports from a large number of mainly retrospective studies showing that mildly elevated homocysteine levels are also associated with venous thromboembolism (VTE ...
Alex, Gatt, Michael, Makris
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Hyperhomocysteinemia and Atherothrombotic Disease
Seminars in Thrombosis and Hemostasis, 1998Hyperhomocysteinemia is an independent risk factor for atherothrombotic disease. The mechanism by which homocysteine induces atherosclerosis and thrombosis is not fully understood. Data on arterial histology in humans with homocystinuria and mild hyperhomocysteinemia are limited.
S C, de Jong +3 more
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Hyperhomocysteinemia After Kidney Transplantation
Transplantation Proceedings, 2011To determine the prevalence of hyperhomocysteinemia (plasma homocysteine[Hcy] concentration≥15 μmol/L) and evaluate its correlation with allograft function.The study included 159 stable renal transplant recipients (104 men and 55 women). The prevalence and severity of hyperhomocysteinemia were compared in the transplant recipients vs 72 patients (48 ...
B, Einollahi +6 more
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Hyperhomocysteinemia and thrombosis
Lipids, 2001AbstractHomocysteine (Hcy) is a sulfhydryl amino acid derived from the metabolic conversion of methionine, which is dependent on vitamins (folic acid, B12, and B6) as cofactors or cosubstrates. In 1969, McCully first reported the presence of severe atherosclerotic lesions in patients with severe hyperhomocysteinemia and hypothesized the existence of a ...
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Hyperhomocysteinemia, inflammation and autoimmunity
Autoimmunity Reviews, 2007Hyperhomocysteinemia is independently associated with the development of coronary, cerebral and peripheral vascular disease and deep-vein thrombosis in the general population. The evidence that cardiovascular involvement is particularly frequent and advanced in patients affected with several autoimmune diseases (AD), in which hyperhomocysteinemia ...
Lazzerini, P. E. +6 more
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Hyperhomocysteinemia and Venous Thromboembolism
Seminars in Thrombosis and Hemostasis, 2006Homocysteine (Hcy) is a sulfhydryl amino acid derived from the metabolic conversion of methionine, which is dependent on vitamins (folic acid, B12 and B6) as cofactors or cosubstrates. Severe hyperhomocysteinemia (homocystinuria), due to inherited metabolic defects of Hcy metabolism, is associated with very high risk of venous thromboembolism (VTE ...
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Hyperhomocysteinemia and Venous Thrombosis
The International Journal of Lower Extremity Wounds, 2002Deep vein thrombosis (DVT) leads to venous ulcers in later life. Venous ulcers are the majority of chronic lower extremity wounds. Recent evidence suggests that hyperhomocysteinemia is an independent risk factor for venous thrombosis. Other evidence suggests that dietary supplementation with folic acids and vitamins helps to change hyper ...
Paul, Lee, Kailash, Prasad
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Hyperhomocysteinemia, Atherosclerosis and Thrombosis
Thrombosis and Haemostasis, 1999SummaryHigh plasma levels of homocysteine are the results of the interplay between congenital and environmental factors. In the last two decades, a growing amount of interest has focused on mild-to-moderate hyperhomocysteinemia as a risk factor of thromboembolic diseases.
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