Results 181 to 190 of about 8,749 (218)
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Monatshefte für Chemie / Chemical Monthly, 1998
Sulfonation of hypericin leads to its di-, tri-, and tetrasulfonic acid derivatives. The latter is soluble in water up to millimolar solutions. Homoaggregate formation (J-aggregates) was observed only above 5ċ10−4 mol/l. In water solutions, the tetrasulfonic acid hypericin derivative was found to be present as its bay-phenolate with most of the ...
Heinz Falk +3 more
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Sulfonation of hypericin leads to its di-, tri-, and tetrasulfonic acid derivatives. The latter is soluble in water up to millimolar solutions. Homoaggregate formation (J-aggregates) was observed only above 5ċ10−4 mol/l. In water solutions, the tetrasulfonic acid hypericin derivative was found to be present as its bay-phenolate with most of the ...
Heinz Falk +3 more
openaire +1 more source
Effect of Acetazolamide on Hypericin Photocytotoxicity
Planta Medica, 2002The photodynamic action of hypericin (HYP) in vitro was evaluated using human leukemic HL-60 and lung carcinoma A549 cell lines. After illumination HYP (1 x 10 (-5) M) reduced the proliferation and/or survival of HL-60 and A549 cells vs. controls to almost to 0 % and 29 %, respectively.
Peter, Solár +8 more
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Molecular Response to Hypericin-Induced Photodamage
Current Medicinal Chemistry, 2012Hypericin (Hyp) is used as a powerful natural photosensitizer in photodynamic therapy (PDT). After selective accumulation in tumor tissue, vessels and matrix, and activated by visible light, it destroys the tumor mainly via generation of reactive oxygen species. After photoactivation, molecular biological mechanisms lead to different cellular endpoints:
B, Krammer, T, Verwanger
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Inhibitory Activity and Mechanism Investigation of Hypericin as a Novel α-Glucosidase Inhibitor
Molecules, 2021Qi Dong
exaly
Umwandlung von Penicilliopsin in Proto‐hypericin und Hypericin
Angewandte Chemie, 1955H. Brockmann, H. Eggers
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