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Diabetes mellitus and white matter hyperintensity [PDF]
White matter hyperintensity (WMH) is a brain lesion detected as a high‐intensity area in magnetic resonance imaging T2 and fluid‐attenuated inversion recovery images, and it has been suggested that WMH reflects damage to small vessels in periventricular and subcortical areas. Although WMH has been linked to the incidence of stroke, more recently it has
Yoshiaki Tamura, Atsushi Araki
exaly +3 more sources
Confluent Thalamic Hyperintensities in CADASIL [PDF]
<i>Background:</i> CADASIL is responsible for diffuse hyperintensities in the white matter on FLAIR images. These lesions are often associated with focal lesions in the basal ganglia such as lacunar infarctions. The prevalence and significance of diffuse or confluent thalamic hyperintensities (CTH) remain unknown. <i>Methods:</i>
Jacqmin, Mathilde+6 more
openaire +4 more sources
MTI of white matter hyperintensities [PDF]
The severity of tissue changes associated with incidental white matter hyperintensities (WMH) in the elderly cannot be sufficiently determined by conventional MRI. We, therefore, performed a regional analysis of the magnetization transfer ratio (MTR) maps obtained on a 1.5 T scanner from 198 neurologically asymptomatic participants of the Austrian ...
Franz Fazekas+6 more
openaire +3 more sources
Early Life Socioeconomic Circumstance and Late Life Brain Hyperintensities : A Population Based Cohort Study [PDF]
Funding: Image acquisition and image analysis for this study was funded by the Alzheimer's Research Trust (now Alzheimer's Research UK). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the ...
A Forsdahl+38 more
core +6 more sources
Neuroticism and white matter hyperintensities
Neuroticism is a major risk factor for neurodegenerative disorders, such as Alzheimer's disease and related dementias. This study investigates whether neuroticism is associated with white matter hyperintensities and whether this measure of brain integrity is a mediator between neuroticism and cognitive function. Middle-aged and older adults from the UK
Antonio Terracciano+8 more
openaire +4 more sources
Periventricular hyperintensity in children with hydrocephalus [PDF]
Magnetic resonance images of children with hydrocephalus often include a rim of hyperintensity in the periventricular white matter (halo).The purpose of this study was to decide between the hypothesis that the halo is caused by cerebrospinal fluid (CSF) flow during the cardiac cycle, and the alternate hypothesis that the halo is caused by anatomical ...
Scott K. Holland+8 more
openaire +3 more sources
White Matter Hyperintensity Penumbra [PDF]
Background and Purpose— White matter hyperintensities (WMHs) are associated with progressive age-related cognitive decline and cardiovascular risk factors, but their biological relevance as indicators of generalized white matter injury is unclear.
Charles DeCarli+6 more
openaire +2 more sources
Hepatic encephalopathy: a neurochemical, neuroanatomical, and neuropsychological study. [PDF]
Hepatic encephalopathy (HE) is normally diagnosed by neuropsychological (NP) tests, which are not very specific and do not reveal the underlying pathology.
Binesh, Nader+11 more
core +1 more source
Prevalence and Risk Factors for Presumptive Ascending/Descending Myelomalacia in Dogs after Thoracolumbar Intervertebral Disk Herniation [PDF]
Background: Ascending/descending myelomalacia (ADMM) is a severe complication of thoracolumbar intervertebral disk herniation (TL-IVDH) in dogs. Hypothesis/Objectives: To investigate the prevalence and risk factors for ADMM in nonambulatory dogs with ...
Aikawa+34 more
core +1 more source
Imaging of Angiogenesis in White Matter Hyperintensities
Background White matter hyperintensities (WMHs) are areas of increased signal intensity on T2‐weighted magnetic resonance imaging (MRI). WMH penumbra may be a potential target for early intervention in WMHs. We explored the relationship between angiogenesis and WMH penumbra in patients with WMHs.
Lingling Ding+6 more
openaire +3 more sources