Results 1 to 10 of about 836 (102)

Sporadic adult‐onset brainstem hyperkalemic periodic paralysis masquerading as recurrent transient ischemic attacks [PDF]

Clinical Case Reports, 2022
We report a case of adult‐onset, sporadic, hyperkalemic periodic paralysis with primary brainstem musculature symptoms masquerading as recurrent transient ischemic attacks. Unilateral brainstem weakness could be induced with rapid eye blinking, which was
Kathryn M.A. Liang, Bertrand C. Liang
doaj   +3 more sources

Discovery and Treatment of Action Potential‐Independent Myotonia in Hyperkalemic Periodic Paralysis [PDF]

Annals of Clinical and Translational Neurology
Objective Hyperkalemic periodic paralysis (hyperKPP) is characterized by attacks of transient weakness. A subset of hyperKPP patients suffers from transient involuntary contraction of muscle (myotonia).
Chris Dupont, Adam Deardorff, Murad Nawaz, Andrew A. Voss, Mark M. Rich   +4 more
doaj   +3 more sources

Hyperkalemic Periodic Paralysis: Case Report with a SCNA4 Gene Mutation and Literature Review [PDF]

Case Reports in Genetics, 2020
Hyperkalemic periodic paralysis is a rare musculoskeletal disorder characterized by episodic muscle weakness associated with hyperkalemia. It is a channelopathy associated with point mutations in the SCNA4 gene, with an autosomal dominant pattern of ...
Manuela Quiroga-Carrillo, Cristian Correa-Arrieta, Fernando Ortiz-Corredor, Fernando Suarez-Obando   +3 more
doaj   +2 more sources

Mitochondrial dysfunction in hyperkalemic periodic paralysis: A case report and literature review [PDF]

BMC Pediatrics
Background Hyperkalemic periodic paralysis is a rare autosomal dominant disorder of sodium channels in skeletal muscles caused by pathogenic variants in the SCN4A gene.
Fady G. Mikhael, Aya S. Yatim, Riyad El-Khoury, Pascale E. Karam   +3 more
doaj   +2 more sources

Familial hyperkalemic periodic paralysis caused by a mutation in the sodium channel gene [PDF]

Korean Journal of Pediatrics, 2011
Familial hyperkalemic periodic paralysis (HYPP) is an autosomaldominant channelopathy characterized by transient and recurrent episodes of paralysis with concomitant hyperkalemia.
Ji-Yeon Han, June-Bum Kim
doaj   +2 more sources

Semaglutide reverses the chronic myopathy of hyperkalemic periodic paralysis: a case report [PDF]

BMC Nephrology
Background Hyperkalemic Periodic Paralysis (hyperPP) is an autosomal dominant genetic disorder where high extracellular potassium is associated with skeletal muscle depolarization and both flaccid muscle weakness as well as delayed muscle relaxation that
Kenneth Brand, Daniel Landry, Jeffrey Mulhern, Gregory Braden   +3 more
doaj   +2 more sources

Efficacy of a K⁺ Channel Agonist, XEN1101, For Preserving Contractility in Mouse Models of Hypokalemic Periodic Paralysis. [PDF]

Muscle Nerve
Pretreatment with an agonist of Kv7 potassium channels (XEN1101) protects the soleus muscle from a loss of force during a 2 mM K+ challenge, in a mouse model of hypokalemic periodic paralysis. ABSTRACT Introduction/Aims Effective management remains lacking for recurrent episodes of acute weakness in hypokalemic periodic paralysis (HypoPP).
Chanchykov V, Iype S, Quinonez M, Wu F, Cannon S.   +4 more
europepmc   +2 more sources

Hyperthyroid Hypokalemic Periodic Paralysis in a Nepali Male; A Case Report. [PDF]

Clin Case Rep
ABSTRACT Hyperthyroid Hypokalemic Periodic Paralysis (HHPP), marked by acute weakness and hypokalemia. Prompt potassium replacement and hyperthyroidism management are essential to prevent life‐threatening outcomes. This case highlights its presentation in a Nepali male, reinforcing the need for high clinical suspicion.
Tamang A, Sapkota P, Humagain S, Dhakal K, Sachdeva C, Shah D, Lamsal P.   +6 more
europepmc   +2 more sources

Hypokalemic Paralysis Is Not Always Periodic: A Case Series. [PDF]

Case Rep Med
Potassium is vital for cellular function, particularly in excitable tissues like nerves and muscles, which rely on potassium gradients to function normally. Hypokalemia can lead to severe issues such as muscle weakness and irregular heart rhythms. This case series presents four instances of hypokalemic paralysis, a neuromuscular condition that can be ...
Mohak Jain, Mehta G, Parmar A, Shastri M, Patel S, Gandhi V, Karatela S, Patel A.   +7 more
europepmc   +2 more sources

Hyperkalemic periodic paralysis in twenty-two family members over four generations: A rare case report [PDF]

Annals of Indian Academy of Neurology, 2023
Ankur Vivek, Pratishtha Sengar, Rameshwar Nath Chaurasia, Abhishek Pathak, Anand Kumar, Varun Kumar Singh   +5 more
doaj   +2 more sources