Results 181 to 190 of about 48,064 (345)

Transforming Growth Factor‐Beta Signaling in Cancer: Therapeutic Implications, Challenges, and Pathways to Progress

MedComm – Oncology, Volume 4, Issue 3, September 2025.
TGF‐β inhibition is emerging as a promising cancer therapy, yet translating laboratory success to bedside implementation has suffered significant setbacks. The associated challenges include adverse drug reactions, inadequate predictive models, and activation of alternative signaling pathways.
Faizah A. Alabi, Izuchukwu F. Okpalanwaka, Adenike Oyegbesan, Ebenezar Okoyeocha, Mariam Oladejo, Sikiru O. Imodoye   +5 more
wiley   +1 more source

A Case of Epidermolytic Ichthyosis with Massive Hyperkeratosis Successfully Treated with Systemic Etretinate [PDF]

, 2023
Eijiro Akasaka, Toshihide Akasaka, Michiyo Nakagawa, Hajime Nakano, Daisuke Sawamura   +4 more
openalex   +1 more source

Hyperkeratosis Blenorrhagica [PDF]

Proceedings of the Royal Society of Medicine, 1921
openaire   +2 more sources

A CASE OF HYPERKERATOSIS PALMARIS ET PLANTARIS ASSOCIATED WITH AINHUM‐LIKE CONSTRICTION OF THE FINGERS

Proceedings of the Royal Society of Medicine, 1929
J. Wigley
semanticscholar   +1 more source

The Genetics of Acne

Annals of Human Genetics, Volume 89, Issue 5, Page 333-341, September 2025.
ABSTRACT This review addresses the genetics of acne vulgaris, the most common skin disease. It is characterized by the presence of comedones (blackheads), papules, and pustules. The condition is associated with sebaceous glands in the face and chest, which produce an oily substance called sebum.
Maurice A. M. Van Steensel
wiley   +1 more source

Acrokeratosis Paraneoplastica-like Findings as a Manifestation of Systemic Lupus Erythematosus

Acta Dermato-Venereologica, 2018
Laura Huilaja, Minna Soronen, Anna Karjalainen, Kaisa Tasanen   +3 more
doaj   +1 more source

Incidencia de la eritroleucoplasia en la cavidad bucal Incidence of erythroleukoplakia in the oral cavity

Medisan, 2012
Se efectuó un estudio descriptivo y transversal de 20 mujeres y hombres mayores de 19 años, adictos al tabaco, atendidos en la consulta estomatológica del Policlínico de Especialidades del Hospital Provincial Docente "Saturnino Lora Torres" de Santiago ...
Gladys Aída Estrada Pereira, Maricel Márquez Filiú, Eugenia González Heredia   +2 more
doaj  

Congenital Variations Discovered in the Clinical Presentation of Hyperkeratosis of the Hand and Foot: A report of 2 cases [PDF]

, 2009
Al Kline
openalex   +1 more source

Safety, tolerability, pharmacokinetics and pharmacodynamics of HSK31858, a novel oral dipeptidyl peptidase‐1 inhibitor, in healthy volunteers: An integrated phase 1, randomized, double‐blind, placebo‐controlled, single‐ and multiple‐ascending dose study

British Journal of Clinical Pharmacology, Volume 91, Issue 8, Page 2262-2272, August 2025.
Abstract Aim Dipeptidyl peptidase‐1 (DPP‐1) inhibitors have been studied for the treatment of neutrophil‐mediated inflammatory diseases including bronchiectasis, bronchial asthma and cystic fibrosis. This study evaluated the pharmacokinetics, pharmacodynamics, safety and tolerability of DPP‐1 inhibitor HSK31858 in healthy Chinese volunteers.
Yuhao Wang, Chao Yu, Mengyue Hu, Lu Wang, Meixia Chen, Hanmo Liu, Nan Wu, Jie Hou   +7 more
wiley   +1 more source

Papular Palmoplantar Hyperkeratosis Following Chronic Medical Exposure to Arsenic: Human Papillomavirus as a Co-factor in the Pathogenesis of Arsenical Keratosis?

, 2000
E. Stockfleth R. Gerdsen
openalex   +1 more source