Results 41 to 50 of about 39,840 (293)

Ontogeny of RSPO1, FOXL2, and RUNX1 during ovarian differentiation in the marsupial tammar wallaby

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background RSPO1 and FOXL2 are female sex‐determining genes involved in the differentiation and organization of the ovary in some eutherian mammals. Mutations or loss of function of these genes are associated with partial to full sex reversal in mice, humans, and goats.
Monika R. Paranjpe   +3 more
wiley   +1 more source

Receptor tyrosine kinase and p16/CDKN2 expression in a case of tripe palms associated with non-small-cell lung cancer [PDF]

open access: yes, 1999
Background: Tripe palms is a descriptive term for a cutaneous paraneoplastic keratoderma. Tripe palms are frequently associated with gastric and pulmonary carcinoma. The pathogenetic mechanism remains unknown.
Bezold, G.   +5 more
core   +1 more source

Loss of the Y Chromosome in Oral Potentially Premalignant Disorders Predicts Malignant Progression: An Integrative Cross‐Species Multi‐Cohort Bioinformatic Study

open access: yesHead &Neck, EarlyView.
ABSTRACT Background The loss of the Y chromosome (LOY) and the extreme down‐regulation of Y chromosome gene expression (EDY) are frequently observed in oral squamous cell carcinoma (OSCC). However, their roles in oral potentially malignant disorders (OPMDs) are unclear.
Rui Han   +6 more
wiley   +1 more source

Gasdermin A (GSDMA) Tissue Expression, Serum and Urinary Concentrations With Clinicopathologic Outcome in Psoriasis

open access: yesDermatology Practical & Conceptual
Introduction: Psoriasis is a frequent and incurable skin disease that is an important issue in contemporary dermatology, whereas its pathogenesis is still uncertain.
Julia Nowowiejska   +6 more
doaj   +1 more source

Laser and radiofrequency for treating genitourinary syndrome of menopause in breast cancer survivors: A systematic review of randomized controlled trial

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Background Breast cancer survivors (BCS) often experience more severe symptoms of genitourinary syndrome of menopause (GSM). As estrogen‐based hormonal therapy is generally avoided in BCS, physical energy methods may offer promising non‐hormonal alternatives.
Nicoli Serquiz   +7 more
wiley   +1 more source

Relationship Between Hyperkeratosis, Teat Conformation Traits, Microbiological Isolation, and Somatic Cell Count in Milk from Dairy Cows

open access: yesDairy
Maintaining teat-end integrity in dairy cows is essential to preventing intramammary infections (IMIs) in dairy cows, yet the relationship between hyperkeratosis, teat conformation, and mammary health remais underexplored.
Leonardo Leite Cardozo   +8 more
doaj   +1 more source

Deafness, palmoplantar hyperkeratosis, and knuckle pads with male-to-male transmission: Bart-Pumphrey syndrome

open access: yesGenetics and Molecular Biology, 2003
We report on a 22-year-old male patient and his father, both presenting with congenital sensorineural deafness, diffuse palmoplantar keratoderma and knuckle pads.
Gisele Viana de Oliveira   +3 more
doaj   +1 more source

Applicability of Novel Laser Scanning Microscopy Techniques in Demonstrating Characteristic Features of Porokeratosis: In Vivo and Ex Vivo Investigation

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Background Porokeratoses represent a group of keratinization disorders characterized histopathologically by the presence of a cornoid lamella. The recognition of porokeratosis as a genodermatosis, along with its association with increased risk of skin cancer, underscores the importance of accurate and timely diagnosis.
Rahime Inci   +5 more
wiley   +1 more source

Penile cutaneous horn

open access: yesUrology Annals, 2020
Cutaneous horns are cornified hyperkeratotic lesions on the skin, usually present on photo-exposed areas such as the face and scalp. Its presence on the penis is very rare.
Diya Pal, Dilip Kumar Pal
doaj   +1 more source

Histopathological Aspects of Common Immune Checkpoint Inhibitors Induced Skin Toxicities

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Background The histological characteristics of checkpoint inhibitors‐related adverse events (cirAEs) are not well studied and there are conflicting data regarding their similarities and differences with their idiopathic counterparts. Objectives To investigate the histological characteristics of the most common cirAEs.
Christina Kemanetzi   +12 more
wiley   +1 more source

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