Results 81 to 90 of about 194,043 (314)

Diagnosing Hyperlipidemia Using Association Rules

, 2008
Data mining methodologies have been developed for exploration and analysis of large quantities of data to discover meaningful patterns and rules. This paper presents a new approach, that employs data mining, to find association rules an effective method ...
Ibrahim Turkoglu, Sengul Dogan
core   +1 more source

Therapy of Canine Hyperlipidemia with Bezafibrate [PDF]

, 2017
BackgroundBezafibrate (BZF) is effective in the treatment of hypertriglyceridemia in human patients, but there are no data on its use in dogs.ObjectiveTo assess the safety of BZF in hyperlipidemic dogs and its efficacy in decreasing serum triglyceride ...
K.S.M. Noronha, E.R. Nakandakare, Casado, TC, Santos, EZ, Florio, JC, V. De Marco, Nakandakare, ER, J.C. Florio, E.Z. Santos, T.C. Casado, C. Gilor, De Marco, V, Noronha, KSM, Gilor, C   +13 more
core   +1 more source

Gut Microbial Release of Ferulic Acid From Germinated Quinoa Alleviates Obesity‐Associated Cognitive Impairment by Activating Hippocampal Mitophagy Associated with PINK1/Parkin Pathway

Advanced Science, EarlyView.
Liberation of ferulic acid by gut microbial feruloyl esterase mediates cognitive enhancement of germinated quinoa (GQF) on obese mice. Ferulic acid enriched in GQF is released by gut microbes Roseburia hominis and R. intestinalis and subsequently mediates the neuroprotective effects of GQF on obesity‐induced cognitive decline by activating hippocampal ...
Yongli Lan, Wengang Zhang, Lei Wang, Shiyang Zhao, Yujie Song, Xinze Wang, Yutang Wang, Xijuan Yang, Shaobo Ma, Junlin Ge, Rui Guo, Xuebo Liu   +11 more
wiley   +1 more source

Hyperlipidemia Is Associated with Chronic Urticaria: A Population-Based Study. [PDF]

, 2016
The etiology of chronic urticaria (CU) is diverse, with chronic infections and inflammation being reported as considerable contributing factors. Although the prevalence of metabolic syndrome was found to be significantly elevated in patients with CU, no ...
Ming-Chieh Tsai, Chao-Hung Chen (502698), Herng-Ching Lin (284636), Shiu-Dong Chung (398440), Shiu-Dong Chung, Ming-Chieh Tsai (341337), Kuo-Hsien Wang (523899), Kuo-Hsien Wang, Chao-Hung Chen, Herng-Ching Lin   +9 more
core   +1 more source

ANGPTL4 Exacerbates Renal Injury in Diabetic Kidney Disease by Impairing Podocyte Lipophagy via Compromised Lysosomal Degradative Function

Advanced Science, EarlyView.
In diabetic kidney disease, elevated podocyte ANGPTL4 is linked to reduced TFEB nuclear localization and compromised lysosomal degradative function. These changes impair podocyte lipophagy and promote lipid‐droplet accumulation and podocyte injury, which may contribute to renal injury progression.
Xiaojing Liu, Shimin Jiang, Zhenkun Yang, Shunlai Shang, Jiayi Li, Guming Zou, Cheng Zhou, Wenge Li   +7 more
wiley   +1 more source

Monogenic hyperlipidemias.

Acta bio-medica : Atenei Parmensis, 2019
Monogenic hyperlipidemias are a group of inherited disorders characterized by elevated plasma concentrations of lipids and lipoproteins. High plasma concentrations of lipids are the most frequent risk factor for cardiovascular disease. Monogenic hyperlipidemias are a minor cause with respect to multifactorial hyperlipidemias.
Krasi, Geraldo, Bushati, Vilma, Precone, Vincenza, Cortese, Bernardo, Agostini, Francesca, Tezzele, Silvia, Baglivo, Mirko, Cecchin, Stefano, Aquilanti, Barbara, Velluti, Valeria, Matera, Giuseppina, Gagliardi, Lucilla, Miggiano, Giacinto Abele Donato, Bertelli, Matteo   +13 more
openaire   +2 more sources

Oxidant stress in hyperlipidemia-induced renal damage

, 2000
Hyperlipoproteinemia can aggravate glomerulosclerosis and chronic tubulointerstitial (ti) damage in kidneys without primary immunologic disease. We evaluated whether the effect of hyperlipidemia on progression of renal damage differed between kidneys ...
Jan Hohbach, Hermann-Josef Gröne, Ralf P. Brandes, Ernst Malle, Christoph J. Olbricht, Autar K. Walli, Hartmut Scheuer, Wilfried Gwinner, Elisabeth F. Gröne   +8 more
core   +1 more source

Germinated brown rice relieves hyperlipidemia by alleviating gut microbiota dysbiosis

, 2023
Hyperlipidemia is a frequent metabolic disorder that is closely associated with diet. It is believed that brown rice, containing the outer bran layer and germ, is beneficial for the remission of hyperlipidemia.
Shan ZHANG, Li-jun GUAN, Jun-ran FENG, Ni-na JI, Chuan-ying REN, Wen-gong HUANG, Di YUAN, Bo LI, Shu-wen LU, Bin HONG, Wei LIU, Di-xin SHA   +11 more
core   +1 more source

Plaque‐Hepatic Targeting Nanotherapy Disrupts the PCSK9‐LOX‐1 Axis to Suppress oxLDL in Atherosclerosis

Advanced Science, EarlyView.
Self‑amplifying PCSK9–LOX‑1 feedback axis drives atherosclerotic progression by promoting oxLDL generation and endothelial uptake. A dual‑targeting nanoplatform (siPCSK9@PEAL NPs‑aL) is constructed to simultaneously silence hepatic PCSK9 for lipid lowering and block plaque LOX‑1 for anti‑inflammation.
Yi Duan, Yijie Qiu, Yan Zhu, Quan Wang, Jiangtao Lin, Yourong Duan, Qi Wang, Yi Dong   +7 more
wiley   +1 more source

Apolipoprotein F is reduced in humans with steatosis and controls plasma triglyceride‐rich lipoprotein metabolism

Hepatology, EarlyView., 2022
Hepatic APOF transcript levels correlate inversely with plasma TG and hepatic steatosis in humans. ApoF expression in mice promotes VLDL‐TG production and lipoprotein remnant clearance in mice. Abstract Background NAFLD affects nearly 25% of the global population. Cardiovascular disease (CVD) is the most common cause of death among patients with NAFLD,
Audrey Deprince, Nathalie Hennuyer, Sander Kooijman, Amanda C. M. Pronk, Eric Baugé, Viktor Lienard, An Verrijken, Eveline Dirinck, Luisa Vonghia, Eloïse Woitrain, Niels J. Kloosterhuis, Eléonore Marez, Pauline Jacquemain, Justina C. Wolters, Fanny Lalloyer, Delphine Eberlé, Sandrine Quemener, Emmanuelle Vallez, Anne Tailleux, Mostafa Kouach, Jean‐Francois Goossens, Violeta Raverdy, Bruno Derudas, Jan Albert Kuivenhoven, Mikaël Croyal, Bart van de Sluis, Sven Francque, François Pattou, Patrick C. N. Rensen, Bart Staels, Joel T. Haas   +30 more
wiley   +1 more source