Results 131 to 140 of about 70,417 (342)

Platelet Prostaglandin Endoperoxides Formation in Hyperlipidemias [PDF]

, 1977
Rena Bizios, Lan K. Wong, R. Vaillancourt, Robert S. Lees, Angelina C. A. Carvalho   +4 more
openalex   +1 more source

GC–MS analysis of oxysterols and their formation in cultivated liver cells (HepG2)

Lipids, Volume 58, Issue 1, Page 41-56, January 2023., 2023
Abstract Oxysterols play a key role in many (patho)physiological processes and they are potential biomarkers for oxidative stress in several diseases. Here we developed a rapid gas chromatographic‐mass spectrometry‐based method for the separation and quantification of 11 biologically relevant oxysterols bearing hydroxy, epoxy, and dihydroxy groups ...
Elisabeth Koch, Mustafa Bagci, Michael Kuhn, Nicole M. Hartung, Malwina Mainka, Katharina M. Rund, Nils Helge Schebb   +6 more
wiley   +1 more source

Target‐Mediated Modeling of Alirocumab in Adolescents and Children ≥8 to <12 Years of Age Using Phase II and III Data

Clinical Pharmacology in Drug Development, EarlyView.
Abstract A population pharmacokinetic (PK) covariate analysis was conducted utilizing data from adolescents and children ≥8 to <12 years of age with heterozygous familial hypercholesterolemia. One phase II and 1 phase III study were analyzed (121 patients on active treatment).
Pavel Kovalenko, Lutz Harnisch, Jeanne Mendell, Yuhuan Wang, John D. Davis, Albert Thomas DiCioccio   +5 more
wiley   +1 more source

The self-limiting nature of statin-induced rhabdomyolysis

Journal of Family and Community Medicine, 2009
Statins have come to the forefront of treatments for hyperlipidemias, coronary artery diseases and strokes. They have been shown to cause myotoxicity and rhabdomyolysis. In most cases, rhabdomyolysis is self-limiting and needs supportive therapy.
Abdulsalam A Al-Sulaiman, Nora I Al-Muslim, Abdulaziz A Al-Quorain, Raed M Al-Sulaiman   +3 more
doaj  

Ischemic Heart Disease and Hyperlipidemia

, 1975
Mitsuo Wada, Kazunari Wada, Junichi Mise
openalex   +2 more sources

Use of Real‐World Claims Data to Assess the Prevalence of Concomitant Medications to Inform Drug–Drug Interaction Risk in Target Patient Populations

Clinical Pharmacology &Therapeutics, EarlyView.
A common issue in clinical drug development involves drug–drug interactions (DDI) that may lead to altered drug exposure and subsequent altered safety and efficacy of an investigational drug or concomitant medications (conmeds) in the target patient population.
Alice S. Tang, Logan Brooks, Denise M. Boudreau, Pascal Chanu, Amita Joshi, Bianca Vora, Rui Zhu   +6 more
wiley   +1 more source

Safety and immunogenicity of mRNA COVID‐19 vaccine in inpatients with muscular dystrophy

Muscle &Nerve, Volume 67, Issue 2, Page 117-123, February 2023., 2023
Abstract Introduction/Aims Due to muscular weakness and cardiopulmonary dysfunction, patients with muscular dystrophy (MD) have an increased risk of serious complications from coronavirus disease‐2019 (COVID‐19). Although vaccination is recommended, COVID‐19 vaccination safety and immunogenicity in these patients are unknown.
Tomoko Saito, Toshio Saito, Hiroya Hashimoto, Katsuhisa Ogata, Michio Kobayashi, Hiroto Takada, Satoshi Kuru, Takashi Kimura, Akinori Nakamura, Tsuyoshi Matsumura   +9 more
wiley   +1 more source

Ketogenic diet therapy for the treatment of pediatric epilepsy

Epileptic Disorders, EarlyView.
Abstract In 1921, the classic ketogenic diet was created at the Mayo Clinic in Rochester, Minnesota to treat epilepsy in children and adults. Over a century later, it is a widely used, standard‐of‐care therapy for typically treatment‐resistant epilepsy worldwide.
Babitha Haridas, Alexander Testino, Eric H. Kossoff   +2 more
wiley   +1 more source

Biochemistry of hyperlipidemia

, 1975
Toshiaki Osuga
openalex   +2 more sources

HYPERLIPIDEMIA IN CHRONIC RENAL INSUFFICIENCY (CRI) THE ROLE OF PARATHORMONE (PTH) [PDF]

, 1977
Z. L. Papadopoulou, Leticia U. Tina, E Sandier, P Jase, E Calcagno   +4 more
openalex   +1 more source