Results 111 to 120 of about 70,014 (324)

The importance and challenge of comparing stroke care, utilization and outcomes in Medicare Advantage and Fee-for-Service Medicare: a narrative review and vision for the future

Journal of Comparative Effectiveness Research
Stroke prevalence is highest in adults ≥65 years, the majority of whom are Medicare beneficiaries. Feefor- Service Medicare (FFS) incentivizes utilization by paying for each service.
Emily J. Bian, Priyanka Menon, Kathleen A. McManus, Timothy J. Layton, Bradford B. Worrall, Jonathan R. Crowe   +5 more
doaj   +1 more source

Hypertriglyceridemia (triglyceride-rich lipoproteins and their remnants): role in development of atherosclerotic cardiovascular diseases and control strategy consensus statement of the expert Committee of the Russian Society of Cardiology (RSC), the National Atherosclerosis Society (NAS), and the Russian Society of Cardiovascular Prevention and Rehabilitation (RosOKR)

КардиоСоматика
This expert consensus document discusses the high prevalence of cardiovascular diseases (CVDs) caused by atherosclerosis. It is now evident that the causes and pathogenesis of atherosclerotic cardiovascular diseases (ASCVD) cannot always be explained ...
Marina G. Bubnova, Marat V. Ezhov, David M. Aronov, Albert S. Galyаvich, Viktor S. Gurevich, Dmitry V. Duplyakov, Vitaliy K. Zafiraki, Natalia S. Karamnova, Vasily V. Kashtalap, Gennady A. Konovalov, Alexey N. Meshkov, Andrey G. Obrezan, Alexander A. Semenkin, Igor V. Sergienko, Alexander E. Filippov   +14 more
doaj   +1 more source

Antihyperlipidemic Agents Cause a Decrease in von Willebrand Factor Levels in Pediatric Patients with Familial Hyperlipidemia

, 2010
Familial hyperlipidemia is a group of genetic disorders with a predisposition to atherosclerosis. Hyperlipidemia causes increased atherosclerotic events through increased endothelial damage.
Şule Ünal, Güneş, B, Fatma Gümrük, Bülent Güneş, Yalçin, SIDDIKA SONGÜL, Turgay Coşkun, Gümrük, FATMA, S. Songül Yalçin, Unal, ŞULE, Coşkun, T   +9 more
core   +1 more source

ATP Citrate Lyase in Metabolic Disease: Mechanistic Insights and Clinical Potential

iNew Medicine, EarlyView.
ATP citrate lyase (ACLY) is a central metabolic hub that diverts mitochondrial citrate to fuel de novo lipogenesis, cholesterol biosynthesis, and protein acetylation. Given its robust correlation with pathological changes in multiple human diseases, ACLY inhibitors featuring distinct pharmacological strengths have been developed for therapeutic ...
Wenbiao Wang, Xinyan Li, Honglu Shi, Gaolei Song, Zhifu Xie, Jingya Li   +5 more
wiley   +1 more source

Hyperlipidemia in Stroke Pathobiology and Therapy: Insights and Perspectives

Frontiers in Physiology, 2018
Romain Menet, Romain Menet, Maxime Bernard, Maxime Bernard, Ayman ElAli, Ayman ElAli   +5 more
doaj   +1 more source

Enhanced peripheral blood mononuclear cell lipid metabolism drives poor immunotherapy response via ferroptotic stress‐induced T cell exhaustion in hepatocellular carcinoma

Interdisciplinary Medicine, EarlyView.
Integrated multi‐omics reveals that CD36‐mediated lipid overload in PBMCs drives T cell exhaustion via sub‐lethal ferroptotic stress and AKT suppression. This systemic metabolic signature serves as a robust predictor of immunotherapy response in HCC, suggesting that modulating lipid metabolism can rescue immune fitness.
Ying Zhu, Zhouyu Ning, Yong Deng, Changjing Huang, Hui Li, Yun Sun, Zhiqiang Meng   +6 more
wiley   +1 more source

Long‐Term Blood Pressure Variability, Hippocampal Subfield Volume and Cognitive Decline: A Population‐Based Prospective MRI Study

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Long‐term blood pressure variability (BPV) is associated with cognitive decline, yet the underlying mechanisms have not been fully elucidated. Purpose To investigate the associations between long‐term BPV and hippocampal subfield volume and cognitive function and to assess the mediation effect of hippocampal subfield volume.
Fei Li, Jing Chen, Huijing Shi, Ling Yang, Xianyu Zhu, Rui Li, Xinyu Zhao, Xiaoliang Liang, Shun Zhang, Yaping Zhang, Han Lv, Jing Li, Shuohua Chen, Yuntao Wu, Ying Hui, Shouling Wu, Zhenchang Wang, Xiaoshuai Li   +17 more
wiley   +1 more source

Primary Hyperlipidemia

Journal of Atherosclerosis and Thrombosis, 2008
Teramoto, Tamio, Sasaki, Jun, Ueshima, Hirotsugu, Egusa, Genshi, Kinoshita, Makoto, Shimamoto, Kazuaki, Daida, Hiroyuki, Biro, Sadatoshi, Hirobe, Kazuhiko, Funahashi, Tohru, Yokote, Koutaro, Yokode, Masayuki   +11 more
openaire   +3 more sources

Correction to “Preoperative Aortic Calcification Volume Predicts Postoperative Complications in Nonpancreatic Cancer Patients Undergoing Pancreaticoduodenectomy”

Annals of Gastroenterological Surgery, EarlyView.
wiley   +1 more source

Impact of Dapagliflozin on MRI‐Derived Epicardial Adipose Tissue: Secondary Imaging Analysis of a Randomized Trial

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Epicardial adipose tissue (EAT) is a metabolically active fat depot associated with cardiovascular risk and represents a modifiable imaging biomarker. Studies have shown that sodium–glucose cotransporter‐2 (SGLT2) inhibitors reduce EAT thickness in patients with type 2 diabetes mellitus (T2DM). However, it is unclear whether this is
Min Jae Cha, Negar Firoozeh, Anna V. Naumova, Peter Muzi, Karen G. Ordovas, Dennis D. Wang, Daniel Isquith, Chuck Maynard, Xue‐Qiao Zhao, Francis Kim   +9 more
wiley   +1 more source