Results 91 to 100 of about 5,058 (261)

Machine Learning Methods to Predict the Length of Stay for Acute Stroke: A Scoping Review and Meta‐Analysis

open access: yesHealth Care Science, EarlyView.
Current machine learning models for predicting the length of stay for acute stroke lack clinical utility and reliability. This scoping review highlights areas for improvement to develop more robust, interpretable, generalizable, and clinically actionable models that optimize personalized clinical pathways and support precise decision‐making for stroke ...
Zhenran Xu   +4 more
wiley   +1 more source

ROSUVASTATIN AS A POSSIBLE TREATMENT FOR SUDDEN SENSORINEURAL HEARING LOSS

open access: yesPakistan Armed Forces Medical Journal, 2019
Objective: To determine the role of Rosuvastatin as a possible treatment of sudden sensorineural hearing loss. Study Design: Quasi-experimental study.
Nadeem Ul Haq   +4 more
doaj  

The importance and challenge of comparing stroke care, utilization and outcomes in Medicare Advantage and Fee-for-Service Medicare: a narrative review and vision for the future

open access: yesJournal of Comparative Effectiveness Research
Stroke prevalence is highest in adults ≥65 years, the majority of whom are Medicare beneficiaries. Feefor- Service Medicare (FFS) incentivizes utilization by paying for each service.
Emily J. Bian   +5 more
doaj   +1 more source

Hypertriglyceridemia (triglyceride-rich lipoproteins and their remnants): role in development of atherosclerotic cardiovascular diseases and control strategy consensus statement of the expert Committee of the Russian Society of Cardiology (RSC), the National Atherosclerosis Society (NAS), and the Russian Society of Cardiovascular Prevention and Rehabilitation (RosOKR)

open access: yesКардиоСоматика
This expert consensus document discusses the high prevalence of cardiovascular diseases (CVDs) caused by atherosclerosis. It is now evident that the causes and pathogenesis of atherosclerotic cardiovascular diseases (ASCVD) cannot always be explained ...
Marina G. Bubnova   +14 more
doaj   +1 more source

Pharmacological effects of gastrodin: Insight into neurological diseases and mechanism in ferroptosis and pyroptosis

open access: yesIbrain, Volume 11, Issue 1, Page 74-83, Spring 2025.
Pharmacological effects of gastrodin include prevention and treatment of cognitive decline and reperfusion injuries, anticonvulsion, antiepilepsy, antidepressants, and analgesia, which are related to antiferroptosis and antipyroptosis. Abstract Gastrodin, as an effective monomer of gastrodia elata, plays a significant role in anti‐inflammatory ...
Xue Zheng, Jing Li, Zhao‐Qiong Zhu
wiley   +1 more source

A New Paradigm: 46 Structural Cell Types Function as Environment‐Supporting Innate Immune Cells, With Endothelial and Vascular Smooth Muscle Cells as Key Prototypes

open access: yesiNew Medicine, EarlyView.
ABSTRACT The scope, organization, and biological significance of innate immune functions across structural cell types remain poorly defined. To address these fundamental knowledge gaps, we analyzed experimental data of transcriptomes generated by our group and others.
Juanjuan Liu   +22 more
wiley   +1 more source

Metrnl: A Novel Therapeutic Target in Atherosclerosis

open access: yesiNew Medicine, EarlyView.
ABSTRACT Atherosclerosis is a chronic inflammatory vascular disease and the main pathological basis of cardiovascular and cerebrovascular events. Exploration of endogenous protective factors in the disease is beneficial for the establishment of new therapeutic strategies.
Pin Wang, Dao‐Xin Wang, Chao‐Yu Miao
wiley   +1 more source

Hyperlipidemia in Stroke Pathobiology and Therapy: Insights and Perspectives

open access: yesFrontiers in Physiology, 2018
Romain Menet   +5 more
doaj   +1 more source

Enhanced peripheral blood mononuclear cell lipid metabolism drives poor immunotherapy response via ferroptotic stress‐induced T cell exhaustion in hepatocellular carcinoma

open access: yesInterdisciplinary Medicine, EarlyView.
Integrated multi‐omics reveals that CD36‐mediated lipid overload in PBMCs drives T cell exhaustion via sub‐lethal ferroptotic stress and AKT suppression. This systemic metabolic signature serves as a robust predictor of immunotherapy response in HCC, suggesting that modulating lipid metabolism can rescue immune fitness.
Ying Zhu   +6 more
wiley   +1 more source

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