Results 71 to 80 of about 70,014 (324)
Background and purpose: Recent data show the antihyperlipidemic activities of some plants belonging to the genus Dracocephalum. In this study, the effects of hydroalcoholic extract of D. subcapitatum (O.
Leila Safaeian +4 more
doaj +1 more source
The present study demonstrated that PFOA and HFPO‐TA exposure suppressed CDK4, disrupted MERCs and impaired PINK1/Parkin‐mediated mitophagy, thereby accelerating cardiac senescence, whereas CAG effectively reversed these pathological changes in vitro. Our findings identify CDK4 as a critical regulator bridging mitophagy defects and cardiac senescence ...
Nuo‐Wa Li +6 more
wiley +1 more source
Background: Probiotics are increasingly recognized for promoting beneficial effects on intestinal health. However, most probiotic strains have been insufficiently researched, underscoring the need for further studies to fully ...
Sisi Chen +4 more
doaj +1 more source
In human CAVD, KLF5 is reduced in VIC‐rich regions and remodeling/stress‐associated VIC states. In VICs, KLF5 sustains BNIP3 promoter activity and BNIP3‐mediated mitophagy, thereby limiting cytosolic mtDNA accumulation. KLF5 loss weakens mitochondrial quality control and enhances mtDNA‐sensitive STING/NF‐κB/NLRP3 inflammatory signaling under osteogenic
Jin‐Hui Bian +13 more
wiley +1 more source
Effect of eight weeks aerobic exercise combined with consumption of almond in men with elevated blood lipids [PDF]
Background: Cardiovascular diseases are one of the main causes of morbidity and mortality in the world that the prevalence is increasing in Iran. This study investigated the effect of almond extract supplement combined with aerobic exercise on lipid ...
MR Almori +2 more
doaj
Introducción. La leptina es una proteína reguladora del peso corporal que modifica sus concentraciones según distintos factores; ha sido asociada con el síndrome metabólico, la diabetes mellitus y la enfermedad cardiovascular. Objetivo.
Elpidia Poveda +4 more
doaj +1 more source
Impact of Acute Functional Decline on Frailty and Mortality in Acutely Hospitalized Older Persons
Older persons with acute functional decline are often severely frail. Male sex, cognitive impairment, diabetes mellitus type 2, cancer, hearing impairment, and nursing home living increase the risk of severe frailty or death and should be considered when person‐centered care is planned for hospitalized older people.
Ali Vahedi +5 more
wiley +1 more source
Objective Lipid-lowering drugs are known to cause various muscle-related side effects; however, it remains unclear whether their use contributes to reduced muscle mass and sarcopenia. This study aimed to evaluate the association between the use of lipid-
Ah-Reum Shin +2 more
doaj +1 more source
ABSTRACT Objective Non‐operative management with antibiotics has emerged as an alternative to appendectomy for uncomplicated appendicitis. This study compared one‐year healthcare costs and utilization outcomes after operative versus non‐operative management of uncomplicated appendicitis using statewide administrative data.
Andrew C. Meltzer +5 more
wiley +1 more source
FUNDAMENTO: Embora dietas hiperlipídicas (DH) promovam distúrbios nutricionais e cardíacos, poucos estudos avaliaram sua influência em ratos normotensos Wistar-Kyoto (WKY) e espontaneamente hipertensos (SHR).
Silvio A. Oliveira Júnior +9 more
doaj +1 more source

