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Healthcare activities before familial hypercholesterolemia diagnosis: a nationwide register-based study in Denmark [PDF]
Background Familial hypercholesterolemia is a common yet underdiagnosed genetic disorder that significantly increases the risk of premature atherosclerotic cardiovascular disease.
Simon Graff +5 more
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Familial hypercholesterolemia is a common genetic disorder of autosomal inheritance associated with elevated LDL-cholesterol. It is estimated to affect 1:250 individuals in general population roughly estimated to be 5 million in India.
J.P.S. Sawhney, Kushal Madan
doaj +3 more sources
Abnormalities in the lipid profile though uncommon in pediatric practice pose an increased risk for developing heart disease. Studies suggest that adult cardiovascular disease has its roots in children and young adults. A significant correlation between atherosclerotic changes in children and young adults and total and LDL cholesterol levels also ...
Sheikh Muhammad Nazir
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Objective: To assess adherence to lipid lowering therapy (LLT), reasons for poor adherence, and achievement of LDL-C treatment goals in children and young adults with familial hypercholesterolemia (FH).
Gisle Langslet +6 more
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Alterations of ileal mucosa-associated microbiota in hypercholesterolemia patients
Many metabolic diseases have been demonstrated to be associated with changes in the microbiome. However, no studies have yet been conducted to examine the characteristics of the mucosal microbiota of patients with hypercholesterolemia.
Jia Li +8 more
doaj +1 more source
The Histomorphological Study on Testicular Cells of Hypercholesterolemia Rats Treated by Polysaccharides of Sea Cucumber, Holothuria nobilis [PDF]
Hypercholesterolemia is a condition characterized by the presence of high levels of plasma cholesterol. This study aims to determine the morphological change of testicular cells in hypercholesterolemia rats treated by polysaccharides of sea cucumber ...
Ulhusna Fitrah A. +2 more
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Familial Hypercholesterolemia [PDF]
Familial hypercholesterolemia is a common, inherited disorder of cholesterol metabolism that leads to early cardiovascular morbidity and mortality. It is underdiagnosed and undertreated. Statins, ezetimibe, bile acid sequestrants, niacin, lomitapide, mipomersen, and low-density lipoprotein (LDL) apheresis are treatments that can lower LDL cholesterol ...
Victoria Enchia, Bouhairie +1 more
openaire +3 more sources
Correlates of Untreated Hypercholesterolemia in Older Adults: A Community-Based Household Survey in China. [PDF]
Hypercholesterolemia is common in older adults and less treated, but little is known about correlates of untreated hypercholesterolemia. Using a standard interview method we examined a random sample of 7,572 participants aged ≥60 years in a community ...
Zhi Hu +4 more
doaj +1 more source
Effects of diet-induced hypercholesterolemia and gold nanoparticles treatment on peripheral tissues
Cholesterol is a lipid molecule of great biological importance to animal cells. Dysregulation of cholesterol metabolism leads to raised blood total cholesterol levels, a clinical condition called hypercholesterolemia.
MATHEUS S. RODRIGUES +10 more
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A comprehensive metabolic profiling of the metabolically healthy obesity phenotype
Background The ever-increasing prevalence of obesity constitutes a major health problem worldwide. A subgroup of obese individuals has been described as “metabolically healthy obese” (MHO).
Vibeke H. Telle-Hansen +4 more
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