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Healthcare activities before familial hypercholesterolemia diagnosis: a nationwide register-based study in Denmark [PDF]

open access: yesBMC Primary Care
Background Familial hypercholesterolemia is a common yet underdiagnosed genetic disorder that significantly increases the risk of premature atherosclerotic cardiovascular disease.
Simon Graff   +5 more
doaj   +2 more sources

Familial hypercholesterolemia

open access: yesIndian Heart Journal
Familial hypercholesterolemia is a common genetic disorder of autosomal inheritance associated with elevated LDL-cholesterol. It is estimated to affect 1:250 individuals in general population roughly estimated to be 5 million in India.
J.P.S. Sawhney, Kushal Madan
doaj   +3 more sources

Familial Hypercholesterolemia

open access: yesGomal Journal of Medical Sciences, 2004
Abnormalities in the lipid profile though uncommon in pediatric practice pose an increased risk for developing heart disease. Studies suggest that adult cardiovascular disease has its roots in children and young adults. A significant correlation between atherosclerotic changes in children and young adults and total and LDL cholesterol levels also ...
Sheikh Muhammad Nazir
doaj   +3 more sources

Thirty percent of children and young adults with familial hypercholesterolemia treated with statins have adherence issues

open access: yesAmerican Journal of Preventive Cardiology, 2021
Objective: To assess adherence to lipid lowering therapy (LLT), reasons for poor adherence, and achievement of LDL-C treatment goals in children and young adults with familial hypercholesterolemia (FH).
Gisle Langslet   +6 more
doaj   +1 more source

Alterations of ileal mucosa-associated microbiota in hypercholesterolemia patients

open access: yesHeliyon, 2023
Many metabolic diseases have been demonstrated to be associated with changes in the microbiome. However, no studies have yet been conducted to examine the characteristics of the mucosal microbiota of patients with hypercholesterolemia.
Jia Li   +8 more
doaj   +1 more source

The Histomorphological Study on Testicular Cells of Hypercholesterolemia Rats Treated by Polysaccharides of Sea Cucumber, Holothuria nobilis [PDF]

open access: yesE3S Web of Conferences, 2020
Hypercholesterolemia is a condition characterized by the presence of high levels of plasma cholesterol. This study aims to determine the morphological change of testicular cells in hypercholesterolemia rats treated by polysaccharides of sea cucumber ...
Ulhusna Fitrah A.   +2 more
doaj   +1 more source

Familial Hypercholesterolemia [PDF]

open access: yesCardiology Clinics, 2015
Familial hypercholesterolemia is a common, inherited disorder of cholesterol metabolism that leads to early cardiovascular morbidity and mortality. It is underdiagnosed and undertreated. Statins, ezetimibe, bile acid sequestrants, niacin, lomitapide, mipomersen, and low-density lipoprotein (LDL) apheresis are treatments that can lower LDL cholesterol ...
Victoria Enchia, Bouhairie   +1 more
openaire   +3 more sources

Correlates of Untreated Hypercholesterolemia in Older Adults: A Community-Based Household Survey in China. [PDF]

open access: yesPLoS ONE, 2015
Hypercholesterolemia is common in older adults and less treated, but little is known about correlates of untreated hypercholesterolemia. Using a standard interview method we examined a random sample of 7,572 participants aged ≥60 years in a community ...
Zhi Hu   +4 more
doaj   +1 more source

Effects of diet-induced hypercholesterolemia and gold nanoparticles treatment on peripheral tissues

open access: yesAnais da Academia Brasileira de Ciências, 2022
Cholesterol is a lipid molecule of great biological importance to animal cells. Dysregulation of cholesterol metabolism leads to raised blood total cholesterol levels, a clinical condition called hypercholesterolemia.
MATHEUS S. RODRIGUES   +10 more
doaj   +1 more source

A comprehensive metabolic profiling of the metabolically healthy obesity phenotype

open access: yesLipids in Health and Disease, 2020
Background The ever-increasing prevalence of obesity constitutes a major health problem worldwide. A subgroup of obese individuals has been described as “metabolically healthy obese” (MHO).
Vibeke H. Telle-Hansen   +4 more
doaj   +1 more source

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