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Genetics of Hypercholesterolemia: Comparison Between Familial Hypercholesterolemia and Hypercholesterolemia Nonrelated to LDL Receptor [PDF]
Frontiers in Genetics, 2020 Severe hypercholesterolemia (HC) is defined as an elevation of total cholesterol (TC) due to the increase in LDL cholesterol (LDL-C) >95th percentile or 190 mg/dl.
Estíbaliz Jarauta +9 more
doaj +3 more sources
Healthcare activities before familial hypercholesterolemia diagnosis: a nationwide register-based study in Denmark [PDF]
BMC Primary CareBackground Familial hypercholesterolemia is a common yet underdiagnosed genetic disorder that significantly increases the risk of premature atherosclerotic cardiovascular disease.
Simon Graff +5 more
doaj +2 more sources
MedicinaBackground and Objectives: Atherosclerotic cardiovascular disease is one of the most common causes of death and disability around the world. Hypercholesterolemia is an established and widely prevalent risk factor; however, the prevalence of severe ...
Urtė Aliošaitienė +6 more
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罕见病研究, 2023 Familial hypercholesterolemia (FH) is a group of autosomal co-dominant genetic diseases mainly characterized by abnormal low-density lipoprotein related metabolism.
FENG Siqin +3 more
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Indian Heart JournalFamilial hypercholesterolemia is a common genetic disorder of autosomal inheritance associated with elevated LDL-cholesterol. It is estimated to affect 1:250 individuals in general population roughly estimated to be 5 million in India.
J.P.S. Sawhney, Kushal Madan
doaj +3 more sources
American Journal of Preventive Cardiology, 2021 Objective: To assess adherence to lipid lowering therapy (LLT), reasons for poor adherence, and achievement of LDL-C treatment goals in children and young adults with familial hypercholesterolemia (FH).
Gisle Langslet +6 more
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The Histomorphological Study on Testicular Cells of Hypercholesterolemia Rats Treated by Polysaccharides of Sea Cucumber, Holothuria nobilis [PDF]
E3S Web of Conferences, 2020 Hypercholesterolemia is a condition characterized by the presence of high levels of plasma cholesterol. This study aims to determine the morphological change of testicular cells in hypercholesterolemia rats treated by polysaccharides of sea cucumber ...
Ulhusna Fitrah A. +2 more
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Alterations of ileal mucosa-associated microbiota in hypercholesterolemia patients
Heliyon, 2023 Many metabolic diseases have been demonstrated to be associated with changes in the microbiome. However, no studies have yet been conducted to examine the characteristics of the mucosal microbiota of patients with hypercholesterolemia.
Jia Li +8 more
doaj +1 more source
Familial Hypercholesterolemia [PDF]
Cardiology Clinics, 2015 Familial hypercholesterolemia is a common, inherited disorder of cholesterol metabolism that leads to early cardiovascular morbidity and mortality. It is underdiagnosed and undertreated. Statins, ezetimibe, bile acid sequestrants, niacin, lomitapide, mipomersen, and low-density lipoprotein (LDL) apheresis are treatments that can lower LDL cholesterol ...
Victoria Enchia, Bouhairie +1 more
openaire +3 more sources
Effects of diet-induced hypercholesterolemia and gold nanoparticles treatment on peripheral tissues
Anais da Academia Brasileira de Ciências, 2022 Cholesterol is a lipid molecule of great biological importance to animal cells. Dysregulation of cholesterol metabolism leads to raised blood total cholesterol levels, a clinical condition called hypercholesterolemia.
MATHEUS S. RODRIGUES +10 more
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