Results 31 to 40 of about 132,170 (308)

The effects of cholesterol accumulation on Achilles tendon biomechanics: A cross-sectional study.

PLoS ONE, 2021
Familial hypercholesterolemia, a common genetic metabolic disorder characterized by high cholesterol levels, is involved in the development of atherosclerosis and other preventable diseases.
Kipling Squier, Alexander Scott, Michael A Hunt, Liam R Brunham, David R Wilson, Hazel Screen, Charlie M Waugh   +6 more
doaj   +1 more source

Effectiveness and safety of PCSK9 inhibitor therapy in patients with familial hypercholesterolemia within a therapeutic program in Poland: Preliminary multicenter data

Cardiology Journal, 2022
BACKGROUND: In Poland, treatment with proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors has become available free of charge in a therapeutic program. Assessed herein, is the efficacy and safety of alirocumab and evolocumab in patients with
Krzysztof Chlebus, Barbara Cybulska, Piotr Dobrowolski, Marzena Romanowska-Kocejko, Marta Żarczyńska-Buchowiecka, Natasza Gilis-Malinowska, Aneta Stróżyk, Justyna Borowiec-Wolna, Marcin Pajkowski, Beata Bobrowska, Renata Rajtar-Salwa, Aleksandra Kwapiszewska, Małgorzata Waluś-Miarka, Magdalena Chmara, Rafał Gałąska, Maciej Małecki, Tomasz Zdrojewski, Marcin Gruchała   +17 more
doaj   +1 more source

Evaluation of the Frequency of Familial Hypercholesterolemia: A Single-Center Experience

Endocrinology Research and Practice, 2019
Objective: Familial hypercholesterolemia is an autosomal dominant disease associated with elevated low-density lipoprotein cholesterol and increased premature atherosclerosis.
Mehmet Ali EREN, Ataman GÖNEL, İsmail KOYUNCU, Ahmet Cebeli GÖKAY, Tevfik SABUNCU   +4 more
doaj   +1 more source

Young women with familial hypercholesterolemia have higher LDL-cholesterol burden than men: Novel data using repeated measurements during 12-years follow-up

Atherosclerosis Plus, 2023
Background and aims: The concentration and the duration of exposure to low-density lipoprotein cholesterol (LDL-C) (LDL-C burden) is an important determinant of risk for cardiovascular disease and thresholds has recently been estimated.
Anja K. Johansen, Martin P. Bogsrud, Jacob J. Christensen, Amanda Rundblad, Ingunn Narverud, Stine Ulven, Gisle Langslet, Kjetil Retterstøl, Kirsten B. Holven   +8 more
doaj   +1 more source

Prevention of High-Fat Diet-Induced Hypercholesterolemia by Lactobacillus reuteri Fn041 Through Promoting Cholesterol and Bile Salt Excretion and Intestinal Mucosal Barrier Functions

Frontiers in Nutrition, 2022
Objectives:Lactobacillus reuteri Fn041 (Fn041) is a probiotic isolated from immunoglobulin A coated microbiota in the human breast milk of Gannan in China with a low incidence of hypercholesterolemia.
Mengyao Lu, Jin Sun, Yuning Zhao, Haowen Zhang, Xinyue Li, Jingbo Zhou, Hongyang Dang, Jidong Zhang, Wenjing Huang, Ce Qi, Duo Li   +10 more
doaj   +1 more source

Sociodemographic sample characteristics by hypercholesterolemia definition.

, 2021
Sociodemographic sample characteristics by hypercholesterolemia definition.
Lindsay M. Jaacks (5420636), Esmaeil Mohammadi (10024381), Joao S. Martins (6416180), Till W. Bärnighausen (8851388), Roy Wong-McClure (9623467), Bolormaa Norov (6416195), Brice Wilfried Bicaba (5896910), Sarah Quesnel-Crooks (6416198), Justine I. Davies (5420639), Rifat Atun (109572), Mohammad-Reza Malekpour (10116358), Sahar Saeedi Moghaddam (8294337), Jennifer Manne-Goehler (3335796), Corine Houehanou (6416165), Mark A. Hlatky (6820211), Pascal Geldsetzer (549621), Farshad Farzadfar (439490), Sebastian Vollmer (388995), Cara Ebert (6416216), Glennis Andall-Brereton (6416150), Mongal Singh Gurung (6416159), Pascal Bovet (58562), Maja E. Marcus (10232903), Michaela Theilmann (5420642)   +23 more
core   +1 more source

Treatment and follow-up of coronary artery disease in a child with homozygous familial hypercholesterolemia

Medicine Science, 2022
Familial hypercholesterolemia is a metabolic disease caused by a mutation in the low-density lipoprotein receptor gene. It carries early atherosclerosis and coronary artery disease risks.
Mehmet Oncul, Cemsit Karakurt, Ozlem Elkiran, Aysehan Akinci, Nevzat Erdil   +4 more
doaj   +1 more source

Changes in the management of hypertension, diabetes mellitus, and hypercholesterolemia in Korean adults before and during the COVID-19 pandemic: data from the 2010-2020 Korea National Health and Nutrition Examination Survey [PDF]

Epidemiology and Health, 2023
OBJECTIVES This study aimed to analyze the changes in chronic disease management indicators, including hypertension, diabetes mellitus, and hypercholesteremia, from 2010-2020 and before (2019) and during (2020) the coronavirus disease 2019 (COVID-19 ...
Yoonjung Kim, Suyeon Park, Kyungwon Oh, Hongseok Choi, Eun Kyeong Jeong   +4 more
doaj   +1 more source

Familial hypercholesterolemia: is it time to separate monogenic from polygenic familial hypercholesterolemia?

, 2020
PURPOSE OF REVIEW: This review explores the concepts of monogenic and the so-called polygenic familial hypercholesterolemia and how the identification of familial hypercholesterolemia as a monogenic condition and its separation from polygenic primary ...
Ray, Kausik K, Brandts, Julia, Dharmayat, K. I., Ray, K. K., Vallejo Vaz, Antonio Javier, Vallejo-Vaz, Antonio J, Brandts, J., Dharmayat, Kanika I   +7 more
core   +1 more source

Modulation of Hypercholesterolemia-Induced Oxidative/Nitrative Stress in the Heart [PDF]

, 2016
Hypercholesterolemia is a frequent metabolic disorder associated with increased risk for cardiovascular morbidity and mortality. In addition to its well-known proatherogenic effect, hypercholesterolemia may exert direct effects on the myocardium ...
Csonka Csaba, Sárközy Márta, Dux, László, Csonka, Csaba, Csont, Tamás Bálint, Dux László, Sárközy, Márta, Pipicz Márton, Pipicz, Márton, Csont Tamás Bálint   +9 more
core   +1 more source