Results 31 to 40 of about 120,195 (312)

Treatment and follow-up of coronary artery disease in a child with homozygous familial hypercholesterolemia

Medicine Science, 2022
Familial hypercholesterolemia is a metabolic disease caused by a mutation in the low-density lipoprotein receptor gene. It carries early atherosclerosis and coronary artery disease risks.
Mehmet Oncul, Cemsit Karakurt, Ozlem Elkiran, Aysehan Akinci, Nevzat Erdil   +4 more
doaj   +1 more source

Mortality Among Patients With Familial Hypercholesterolemia: A Registry‐Based Study in Norway, 1992–2010 [PDF]

, 2014
Background Untreated patients with familial hypercholesterolemia are at increased risk of premature cardiovascular death. The primary aim of this study was to investigate whether this is also the case in the statin era.
Retterstøl, Kjetil, Veierød, Marit B., Mundal, Liv, Leren, Trond P., Iversen, Per Ole, Ose, Leiv, Borgan, Jens‐Kristian, Sarancic, Mirza   +7 more
core   +1 more source

Prevalence of Hypercholesterolemia and Awareness of Risk Factors, Prevention and Management Among Adults Visiting Referral Hospital in Ethiopia [PDF]

, 2023
Aychew Kassa Belete,1 Abebe Tarekegn Kassaw,2 Bantie Getnet Yirsaw,3 Birhan Ambachew Taye,3 Samueal Nigatie Ambaw,1 Biset Asrade Mekonnen,4 Ashenafi Kibret Sendekie5 1Department of Sport Science, Faculty of Natural and Computational Science, Woldia ...
Kassaw AT, Ambaw SN, Yirsaw BG, Belete AK, Mekonnen BA, Sendekie AK, Taye BA   +6 more
core  

Antioxidants level in serum of patients with high cholesterol [PDF]

مجلة التربية والعلم, 2008
This study included evaluation the relationship between cholesterol and antioxidants level in the human with hypercholesterolemia . Blood of 33 samples were collected from patients with hypercholesterolemia 18 male and 15 female with age ranging between (
Ameera Hamdoon
doaj   +1 more source

The economic impact of hypercholesterolemia and mixed dyslipidemia: A systematic review of cost of illness studies.

PLoS ONE, 2021
Hypercholesterolemia is a clinically relevant condition with an ascertained role in atherogenesis. In particular, its presence directly correlates to the risk of atherosclerotic cardiovascular disease (ASCVD).
Pietro Ferrara, Danilo Di Laura, Paolo A Cortesi, Lorenzo G Mantovani   +3 more
doaj   +1 more source

Familial hypercholesterolemia

Saudi Medical Journal, 2007
Familial homozygous hypercholesterolemia is a rare autosomal disorder characterized by high levels of cholesterol, extensive tendon xanthomatosis and premature development of atherosclerotic disease. Early coronary artery disease with myocardial infarctions and sudden deaths are common.
Parvaiz A, Koul, Rafi A, Jan, Abdul B, Wahid, Tariq A, Bhat, Syed M, Mudassir   +4 more
openaire   +2 more sources

Efficacy and Safety of Alirocumab as Add-on Therapy in High–Cardiovascular-Risk Patients With Hypercholesterolemia Not Adequately Controlled With Atorvastatin (20 or 40 mg) or Rosuvastatin (10 or 20 mg)::Design and Rationale of the ODYSSEY OPTIONS Studies [PDF]

, 2014
The phase 3 ODYSSEY OPTIONS studies (OPTIONS I, NCT01730040; OPTIONS II, NCT01730053) are multicenter, multinational, randomized, double-blind, active-comparator, 24-week studies evaluating the efficacy and safety of alirocumab, a fully human monoclonal ...
Peter H. Jones, Robinson, Jennifer G., Hanotin, Corinne, Du, Yunling, Jones, Peter H., Harold E. Bays, Corinne Hanotin, Yunling Du, Colhoun, Helen M., Donahue, Stephen, Jennifer G. Robinson, Helen M. Colhoun, Stephen Donahue, Bays, Harold E.   +13 more
core   +1 more source

Lipoprotein(a) in children and adolescents with genetically confirmed familial hypercholesterolemia followed up at a specialized lipid clinic

Atherosclerosis Plus
Background and aim: Many children with an FH mutation also exhibit elevated lipoprotein(a) levels, which is an independent risk factor for atherosclerotic cardiovascular disease.
Anja K. Johansen, Martin P. Bogsrud, Magne Thoresen, Jacob J. Christensen, Ingunn Narverud, Gisle Langslet, Tone Svilaas, Kjetil Retterstøl, Kirsten B. Holven   +8 more
doaj   +1 more source

Familial hypercholesterolemia: is it time to separate monogenic from polygenic familial hypercholesterolemia? [PDF]

, 2020
PURPOSE OF REVIEW: This review explores the concepts of monogenic and the so-called polygenic familial hypercholesterolemia and how the identification of familial hypercholesterolemia as a monogenic condition and its separation from polygenic primary ...
Ray, Kausik K, Brandts, Julia, Dharmayat, K. I., Ray, K. K., Vallejo Vaz, Antonio Javier, Vallejo-Vaz, Antonio J, Brandts, J., Dharmayat, Kanika I   +7 more
core   +1 more source

Defining Features of Gabriele‐de Vries Syndrome in Adults: A Case Report and Literature Review

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Gabriele‐de Vries syndrome (GADEVS) is a neurodevelopmental disorder caused by heterozygous pathogenic variants in the YY1 gene. Like most rare genetic syndromes, the adult manifestations of GADEVS remain poorly defined. Here, we describe the oldest patient reported to date with GADEVS—a 63‐year‐old woman with a c.1177_1179del YY1 variant ...
Ethan W. Hollingsworth, Changrui Xiao
wiley   +1 more source