Results 31 to 40 of about 128,840 (306)

Effectiveness and safety of PCSK9 inhibitor therapy in patients with familial hypercholesterolemia within a therapeutic program in Poland: Preliminary multicenter data

Cardiology Journal, 2022
BACKGROUND: In Poland, treatment with proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors has become available free of charge in a therapeutic program. Assessed herein, is the efficacy and safety of alirocumab and evolocumab in patients with
Krzysztof Chlebus, Barbara Cybulska, Piotr Dobrowolski, Marzena Romanowska-Kocejko, Marta Żarczyńska-Buchowiecka, Natasza Gilis-Malinowska, Aneta Stróżyk, Justyna Borowiec-Wolna, Marcin Pajkowski, Beata Bobrowska, Renata Rajtar-Salwa, Aleksandra Kwapiszewska, Małgorzata Waluś-Miarka, Magdalena Chmara, Rafał Gałąska, Maciej Małecki, Tomasz Zdrojewski, Marcin Gruchała   +17 more
doaj   +1 more source

Evaluation of the Frequency of Familial Hypercholesterolemia: A Single-Center Experience

Endocrinology Research and Practice, 2019
Objective: Familial hypercholesterolemia is an autosomal dominant disease associated with elevated low-density lipoprotein cholesterol and increased premature atherosclerosis.
Mehmet Ali EREN, Ataman GÖNEL, İsmail KOYUNCU, Ahmet Cebeli GÖKAY, Tevfik SABUNCU   +4 more
doaj   +1 more source

Young women with familial hypercholesterolemia have higher LDL-cholesterol burden than men: Novel data using repeated measurements during 12-years follow-up

Atherosclerosis Plus, 2023
Background and aims: The concentration and the duration of exposure to low-density lipoprotein cholesterol (LDL-C) (LDL-C burden) is an important determinant of risk for cardiovascular disease and thresholds has recently been estimated.
Anja K. Johansen, Martin P. Bogsrud, Jacob J. Christensen, Amanda Rundblad, Ingunn Narverud, Stine Ulven, Gisle Langslet, Kjetil Retterstøl, Kirsten B. Holven   +8 more
doaj   +1 more source

Prevention of High-Fat Diet-Induced Hypercholesterolemia by Lactobacillus reuteri Fn041 Through Promoting Cholesterol and Bile Salt Excretion and Intestinal Mucosal Barrier Functions

Frontiers in Nutrition, 2022
Objectives:Lactobacillus reuteri Fn041 (Fn041) is a probiotic isolated from immunoglobulin A coated microbiota in the human breast milk of Gannan in China with a low incidence of hypercholesterolemia.
Mengyao Lu, Jin Sun, Yuning Zhao, Haowen Zhang, Xinyue Li, Jingbo Zhou, Hongyang Dang, Jidong Zhang, Wenjing Huang, Ce Qi, Duo Li   +10 more
doaj   +1 more source

Hypercholesterolemia [PDF]

, 2015
This book is aimed to accentuate the importance of hypercholesterolemia, since targeting and treating the hypercholesterolemia is increasingly well known as an essential strategy in the prevention of atherosclerosis-induced cardiovascular disease.

core   +1 more source

Treatment and follow-up of coronary artery disease in a child with homozygous familial hypercholesterolemia

Medicine Science, 2022
Familial hypercholesterolemia is a metabolic disease caused by a mutation in the low-density lipoprotein receptor gene. It carries early atherosclerosis and coronary artery disease risks.
Mehmet Oncul, Cemsit Karakurt, Ozlem Elkiran, Aysehan Akinci, Nevzat Erdil   +4 more
doaj   +1 more source

Familial hypercholesterolemia

Saudi Medical Journal, 2007
Familial homozygous hypercholesterolemia is a rare autosomal disorder characterized by high levels of cholesterol, extensive tendon xanthomatosis and premature development of atherosclerotic disease. Early coronary artery disease with myocardial infarctions and sudden deaths are common.
Parvaiz A, Koul, Rafi A, Jan, Abdul B, Wahid, Tariq A, Bhat, Syed M, Mudassir   +4 more
openaire   +2 more sources

Secondary (acquired) hypercholesterolemia

, 2022
Elevated cholesterol serum level is a leading cause of atherosclerosis and related diseases, such as coronary, ischemic cerebrovascular, and peripheral vascular disease.
Cincione I. R., Cicero, Arrigo F. G., Cincione, Ivan R., Cicero A. F. G.   +3 more
core   +1 more source

Novel drugs in the treatment of hypercholesterolemia

, 2022
My thesis focuses on different modalities to be explored in the treatment of hypercholesterolemia. Various new drugs include: Microsomal transfer protein (MTP) inhibitors, Inhibition of ANGPTL3, and Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9 ...
Ismail, Omar
core  

LDLR-Gene therapy for familial hypercholesterolaemia: Problems, progress, and perspectives [PDF]

, 2010
Coronary artery diseases (CAD) inflict a heavy economical and social burden on most populations and contribute significantly to their morbidity and mortality rates.
Charles Coutelle, Harbottle, R, Anna L David, Themis, M, Al-Allaf, FA, Waddington, SN, David, A, Faisal A Al-Allaf, Michael Themis, Coutelle, C, Simon N Waddington, Richard Harbottle   +11 more
core   +1 more source