Results 51 to 60 of about 120,195 (312)

A Scoping Review of Electronic Health Records–Based Screening Algorithms for Familial Hypercholesterolemia [PDF]

BackgroundFamilial hypercholesterolemia (FH) is a common genetic disorder that is strongly associated with premature cardiovascular disease. Effective diagnosis and appropriate treatment of FH can reduce cardiovascular disease risk; however, FH is ...
Khoury, Muin J., Otchere, Baffour, Osei, Jeffery, Coronado, Fatima, Akyea, Ralph K., Bonful, Gracelove, Razavi, Alexander C., Akoto, Natalie, Kolor, Katherine, Mensah, George A., Sperling, Laurence, Moonesinghe, Ramal, Qureshi, Nadeem   +12 more
core   +2 more sources

Molecular basis of familial hypercholesterolemia [PDF]

, 2017
Purpose of review To provide an overview about the molecular basis of familial hypercholesterolemia. Recent findings Familial hypercholesterolemia is a common hereditary cause of premature coronary heart disease. It has been estimated that 1 in every 250
Hovingh, Gerard K., Gerard K. Hovingh, Caroline S. Bruikman, Bruikman, Caroline S., John J.P. Kastelein, Kastelein, John J. P.   +5 more
core   +1 more source

Ocular manifestations of severe familial hypercholesterolemia

Heliyon
Background: To study ocular manifestations of patients with severe familial hypercholesterolemia (FH). Methods: In this population-based case-control study, patients suffering from severe familial hypercholesterolemia from the Lebanese Familial ...
Alaa Bou Ghannam, Rachid Istambouli, Mohamed S. Hamam, Jean M. Chalhoub, Akl C. Fahed, Rola N. Hamam   +5 more
doaj   +1 more source

Epidemiology of hypercholesterolemia [PDF]

Vnitřní lékařství, 2018
Hypercholesterolemia is one of the most important risk factors of cardiovascular (CV) disease. Epidemiology follows the prevalence, the incidence and the possibilities of risk factors or diseases intervention. A review of observation epidemiologic studies, pharmacotherapy and treatment perspectives is presented.
Barbora, Nussbaumerová, Hana, Rosolová
openaire   +2 more sources

A Metabolomic Signature Predicts Gout Flare Clinical Outcome Associated With Colchicine Prophylaxis

Arthritis &Rheumatology, EarlyView.
Objective This study investigated that serum metabolomics, before urate‐lowering therapy (ULT) initiation, could serve as a biomarker for responsiveness to colchicine prophylaxis in patients with gout commencing treat‐to‐target ULT. Methods We studied a multicenter prospective cohort (n = 409) initiating treat‐to‐target ULT plus colchicine prophylaxis.
Wenyan Sun, Lingfang Xu, Haibing Chen, Mingshu Sun, Zhiqiang Li, Rui Li, Lidan Ma, Hui Zhang, Aichang Ji, Yuwei He, Na Wu, Le Yan, Robert Terkeltaub, Changgui Li   +13 more
wiley   +1 more source

Doppler study of cerebral arteries in hypercholesterolemia [PDF]

, 2011
Mehdi Farhoudi1, Kaveh Mehrvar2, Naser Aslanabadi3, Kamyar Ghabili1, Nazila Rasi Baghmishe4, Farzad Ilkhchoei41Neuroscience Research Center, 2Razi Hospital, 3Department of Cardiology, 4Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz ...
Ghabili K
core  

Uji Ekstrak n-Hexana Rumput Kebar (Biophytum petersianum Klotzsch) pada Tikus Wistar Hiperkolesterolemia [PDF]

, 2019
This study was aimed to determine the secure level of the n-hexane extract of kebar grass on hypercholesterolemia rats based the acute oral toxicity test.
Baaka, Alnita, Susmiati, Trini, Purwaningsih, Purwaningsih, Airin, Claude Mona, Sambodo, Priyo   +4 more
core   +2 more sources

Plant sterols for adults with hypercholesterolemia treated with or without medication (statins)

Revista Española de Nutrición Humana y Dietética, 2015
Hypercholesterolemia is the most common coronary risk factor among the Spanish population; 37.4% of the Spanish adult population have cholesterol levels between 190 and 240 mg/dl.
Raquel Bernácer, Diana Roig, Blanca Lozano   +2 more
doaj   +1 more source

Decoding RNA regulation: Challenges and opportunities for RNA‐based therapies in Europe

British Journal of Clinical Pharmacology, EarlyView.
Abstract RNA‐based medicinal products represent a promising frontier in personalised medicine, offering sequence‐specific disease targeting at various molecular levels, yet their clinical translation in the European Union (EU) may be hindered by regulatory uncertainty around definitions and evidence requirements; this study therefore aims to identify ...
Olivia C. Lewis, Christine Leopold, Joyce M. Hoek, Raymond M. Schiffelers, Marie L. De Bruin   +4 more
wiley   +1 more source

Relationship Of Waist Circumference And Hypercholesterolemia Incidence In Patient With Hypertension in Tegal Gundil Public Health Center at Bogor City

Jurnal Kesehatan Komunitas (Journal of Community Health), 2019
Hypertension and hypercholesterolemia are the causes of coronary heart disease (CHD) so that the presence of hypercholesterolemia in patients with hypertension will increase the risk of CHD.
Siti Hana, Ratu Ayu Dewi Sartika
doaj   +1 more source