Results 51 to 60 of about 119,690 (213)

Data on circulating leukocyte subpopulations and inflammatory proteins in children with familial hypercholesterolemia and healthy children

Data in Brief, 2017
The data in this relies on a previous publication: “Altered leukocyte distribution under hypercholesterolemia: a cross-sectional study in children with familial hypercholesterolemia” (Christensen et al. 2016) [1].
Jacob J. Christensen, Liv Osnes, Bente Halvorsen, Kjetil Retterstøl, Martin P. Bogsrud, Cecilie Wium, Arne Svilaas, Ingunn Narverud, Stine M. Ulven, Pål Aukrust, Kirsten B. Holven   +10 more
doaj   +1 more source

Hypercholesterolemia and a candidate gene within the 12q24 locus

Cardiovascular Diabetology, 2011
Background The 12q24 locus entails at least one gene responsible for hypercholesterolemia. Within the 12q24 locus lies the gene of proteasome modulator 9 (PSMD9). PSMD9 is in linkage with type 2 diabetes (T2D), T2D-nephropathy and macrovascular pathology
Gragnoli Claudia
doaj   +1 more source

Familial hypercholesterolemia: is it time to separate monogenic from polygenic familial hypercholesterolemia?

, 2020
PURPOSE OF REVIEW: This review explores the concepts of monogenic and the so-called polygenic familial hypercholesterolemia and how the identification of familial hypercholesterolemia as a monogenic condition and its separation from polygenic primary ...
Ray, Kausik K, Brandts, Julia, Dharmayat, K. I., Ray, K. K., Vallejo Vaz, Antonio Javier, Vallejo-Vaz, Antonio J, Brandts, J., Dharmayat, Kanika I   +7 more
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LDLR-Gene therapy for familial hypercholesterolaemia: Problems, progress, and perspectives

, 2010
Coronary artery diseases (CAD) inflict a heavy economical and social burden on most populations and contribute significantly to their morbidity and mortality rates.
Charles Coutelle, Harbottle, R, Anna L David, Themis, M, Al-Allaf, FA, Waddington, SN, David, A, Faisal A Al-Allaf, Michael Themis, Coutelle, C, Simon N Waddington, Richard Harbottle   +11 more
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Hypoxia-induced NOS1 as a therapeutic target in hypercholesterolemia-related colorectal cancer

Cancer & Metabolism
Background It is well established that hypercholesterolemia increases the risk of atherosclerosis, especially because it reduces the availability of nitric oxide (NO). However, the relationship between hypercholesterolemia and NO in regulating colorectal
Weiqing Qiu, Li Zhao, Hua Liu, Ping Xu, Changlin Qian   +4 more
doaj   +1 more source

Predictive value of systemic inflammation response index for atherosclerotic cardiovascular disease risk in patients with hypercholesterolemia: a machine learning study with dual-cohort validation

Lipids in Health and Disease
Background Residual cardiovascular risk persists in patients with hypercholesterolemia despite lipid-lowering therapy, underscoring the importance of inflammation in ASCVD development.
Yu Chen, Weikang Huang, Shihan Zhao, Zhuoqi Ge, Yan Liu, Ruibing Huang, Dongmei Li, Qing Xu, Xingzhen Long, Kai Wei, Qi Chen, Changcheng Sheng, Cailin Tang, Xue Bai   +13 more
doaj   +1 more source

Increased waist circumference as an independent predictor of hypercholesterolemia in community-dwelling older people

Healthcare in Low-resource Settings, 2018
Hypercholesterolemia is a worldwide public health problem, contributing to cerebrovascular and ischemic heart diseases as one of the major cardiovascular risk factors, and associated with approximately 4.4 million deaths each year worldwide.
Claudineia Matos de Araujo, Marcos Henrique Fernandes, José Ailton Oliveira Carneiro, Raildo da Silva Coqueiro, Rafael Pereira   +4 more
doaj   +1 more source

Pitavastatin approved for treatment of primary hypercholesterolemia and combined dyslipidemia

, 2010
Jun SasakiPharmaceutical Medicine, International University of Health and Welfare Graduate School, Fukuoka, JapanAbstract: Pitavastatin was first developed in Japan and is expanding the regions in which it is clinically available.
Jun Sasaki
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THE REDUCTION OF CHOLESTEROL WITH CUPPING THERAPY ON CHOLESTEROL REDUCTION IN PATIENTS WITH HYPERCHOLESTEROLEMIA

Jurnal Ners, 2017
Introduction: Hypercholesterolemia is a risk factor causes of death at younger ages. Hypercholesterolemia may increase the risk of atherosclerosis, coronary heart disease, pancreatitis (pancreas inflammation in organs), diabetes mellitus, thyroid ...
Zahid Fikri, Nursalam Nursalam, Eka Mishbahatul Mar'ah Has   +2 more
doaj   +1 more source

Treatment of Familial Hypercholesterolemia

, 2018
Familial hypercholesterolemia is the most prevalent genetic disorder with a autosomal dominant background. Early detection of the condition is important, diagnosing the disease is easily missed in most of the cases until some abnormally early CVD ...
Alharshani, Bushra Farhan M
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