Results 61 to 70 of about 132,170 (308)
The effect of diets containing different proportions of buckwheat on intestinal function of cholesterol absorption and excretion and intestinal microbiota in hypercholesterolemic mice were studied.The mice were divided into four groups where they were ...
TIAN Tian, PEI Xin-li, LIU Hai-ying
doaj +1 more source
Epidemiology of hypercholesterolemia [PDF]
Hypercholesterolemia is one of the most important risk factors of cardiovascular (CV) disease. Epidemiology follows the prevalence, the incidence and the possibilities of risk factors or diseases intervention. A review of observation epidemiologic studies, pharmacotherapy and treatment perspectives is presented.
Barbora, Nussbaumerová, Hana, Rosolová
openaire +2 more sources
Hypercholesterolemia: A disease with expression from childhood
Hypercholesterolemia results from an alteration, genetic or acquired, in lipoprotein metabolism. Evidence that hypercholesterolemia is associated with the atherosclerotic process from childhood justifies the screening of high-risk children and initiation
Vasconcelos, C. +5 more
core +1 more source
Organic solvent‐free lipid nanoparticles featuring PEtOx‐based stealth lipids enable efficient mRNA and CRISPR‐Cas9 delivery while exhibiting markedly improved biocompatibility compared with PEG‐based analogues. Their successful ex vivo and in vivo performance, combined with data‐driven formulation optimization, establishes a versatile platform that ...
Michael Streiber +21 more
wiley +1 more source
Engineering Biology Beyond Single Genes: Advances and Challenges in Multiplex Genome Editing
Multiplex genome editing is transforming genome engineering from single‐gene perturbation to network‐level control, yet its broader application remains limited by challenges in gRNA array engineering, delivery technologies, and safety management. Emerging AI‐driven approaches are accelerating guide RNA design and CRISPR effector optimization for ...
Linli Wang, Yongbin Liu, Hongbing Han
wiley +1 more source
Lipoprotein-X: A Case of Falsely Elevated LDL Hypercholesterolemia
Lipoprotein-X is an extremely rare cause of severe hyperlipidemia. We present a case of a 26-year-old man with primary sclerosing cholangitis who developed lipoprotein X-induced pseudohyponatremia with severe hyponatremia.
Jacob Y. Mok, MD, Jaime Burkle, MD
doaj +1 more source
EXPERIMENTAL HYPERCHOLESTEROLEMIA [PDF]
n ...
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ASPECTS OF DETECTING PATIENTS WITH FAMILY HYPERCHOLESTEROLEMIA
The review presents current data regarding the etiology and epidemiology of familial hypercholesterolemia (FH), algorithms for identifying patients with FH using clinical scales, genetic testing, cascade screening.
N Yu Dranenko +3 more
core +1 more source
Purpose To compare clinical outcomes and ultrasound‐assessed healing rates between posterosuperior and anterior rotator cuff repairs using propensity score matching. Methods Consecutive patients undergoing rotator cuff repair between 2015 and 2021 by a single fellowship‐trained shoulder surgeon were included if they had posterosuperior or anterior ...
Mustafa S. Rashid +6 more
wiley +1 more source
Purpose To determine whether diabetes mellitus is associated with higher systemic and hip‐specific complications and to evaluate reoperation rates after hip arthroscopy. Methods Using the TriNetX Research Network and Current Procedural Terminology and International Classification of Diseases codes, we identified diabetic and nondiabetic patients aged ...
Nicholas J. Morriss +3 more
wiley +1 more source

