Results 61 to 70 of about 119,690 (213)

A Scoping Review of Electronic Health Records–Based Screening Algorithms for Familial Hypercholesterolemia

BackgroundFamilial hypercholesterolemia (FH) is a common genetic disorder that is strongly associated with premature cardiovascular disease. Effective diagnosis and appropriate treatment of FH can reduce cardiovascular disease risk; however, FH is ...
Khoury, Muin J., Otchere, Baffour, Osei, Jeffery, Coronado, Fatima, Akyea, Ralph K., Bonful, Gracelove, Razavi, Alexander C., Akoto, Natalie, Kolor, Katherine, Mensah, George A., Sperling, Laurence, Moonesinghe, Ramal, Qureshi, Nadeem   +12 more
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Molecular basis of familial hypercholesterolemia

, 2017
Purpose of review To provide an overview about the molecular basis of familial hypercholesterolemia. Recent findings Familial hypercholesterolemia is a common hereditary cause of premature coronary heart disease. It has been estimated that 1 in every 250
Hovingh, Gerard K., Gerard K. Hovingh, Caroline S. Bruikman, Bruikman, Caroline S., John J.P. Kastelein, Kastelein, John J. P.   +5 more
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Doppler study of cerebral arteries in hypercholesterolemia

, 2011
Mehdi Farhoudi1, Kaveh Mehrvar2, Naser Aslanabadi3, Kamyar Ghabili1, Nazila Rasi Baghmishe4, Farzad Ilkhchoei41Neuroscience Research Center, 2Razi Hospital, 3Department of Cardiology, 4Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz ...
Ghabili K
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Uji Ekstrak n-Hexana Rumput Kebar (Biophytum petersianum Klotzsch) pada Tikus Wistar Hiperkolesterolemia

, 2019
This study was aimed to determine the secure level of the n-hexane extract of kebar grass on hypercholesterolemia rats based the acute oral toxicity test.
Baaka, Alnita, Susmiati, Trini, Purwaningsih, Purwaningsih, Airin, Claude Mona, Sambodo, Priyo   +4 more
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Association between height and hypercholesterolemia in adults: a nationwide population-based study in Korea

Lipids in Health and Disease, 2019
Background Previous studies reported that stature is inversely related to the risk of cardiovascular disease. However, there is limited evidence on the association between height and lipid profiles.
Mi Yeon Lee, Ga Eun Nam, Kyungdo Han, Da Hye Kim, Yang Hyun Kim, Kyung Hwan Cho, Yong Gyu Park   +6 more
doaj   +1 more source

Causal relationship between mental disorders and hypercholesterolemia： a Mendelian randomization analysis

Sichuan jingshen weisheng
BackgroundMetabolic syndrome （MetS） is highly prevalent in patients with mental disorders， including elevated diastolic or systolic blood pressure， elevated fasting glucose， hypercholesterolemia， abdominal obesity and so on.
Zou Qian, Tang Ni, Liu Huanhui, Zhang Hanjing, Ma Xiaojie   +4 more
doaj   +1 more source

Increased body mass and depressive symptomatology are associated with hypercholesterolemia, among elderly individuals; results from the MEDIS study

Lipids in Health and Disease, 2009
Background Hypercholesterolemia is one of the most important factors causing cardiovascular disease (CVD). The aim of the present work was to evaluate the relationships between socio-demographic, clinical, lifestyle and depression status and the presence
Makri Kornilia, Metallinos George, Papairakleous Natassa, Katsarou Alexia, Micheli Mary, Bountziouka Vassiliki, Zeimbekis Akis, Lionis Christos, Tyrovolas Stefanos, Polychronopoulos Evangelos, Panagiotakos Demosthenes B   +10 more
doaj   +1 more source

Targeted genetic testing for familial hypercholesterolaemia using next generation sequencing:a population-based study [PDF]

, 2014
BACKGROUND: Familial hypercholesterolaemia (FH) is a common Mendelian condition which, untreated, results in premature coronary heart disease. An estimated 88% of FH cases are undiagnosed in the UK.
Soutar, Anne K., Shona M Kerr, Jennifer Biggs, Anne K Soutar, Aitman, Timothy J., Porteous, David J, Morris, Andrew D., Morris, Andrew D, Scotland, Generation, Blair H Smith, Generation Scotland, Smith, Blair H, Anna F Dominiczak, Thomas, Ellen, Soutar, Anne K, Vandrovcova, Jana, Kerr, Shona M, Kerr, Shona M., Archie Campbell, Biggs, Jennifer, Norsworthy, Penny J, David J Porteous, Laurence Game, Thomas, Ellen R. A., Game, Laurence, Penny J Norsworthy, Smith, Blair H., Norsworthy, Penny J., Campbell, Archie, Porteous, David J., Aitman, Timothy J, Ellen RA Thomas, Dominiczak, Anna F, Smith, Blair H.; id_orcid, Jana Vandrovcova, ?, ?, Dominiczak, Anna F., Thomas, Ellen RA, Timothy J Aitman, Andrew D Morris   +39 more
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Familial hypercholesterolemia: experience from France

, 2018
International audiencePurpose of review We provide an overview of molecular diagnosis for familial hypercholesterolemia in France including descriptions of the mutational spectrum, polygenic susceptibility and perspectives for improvement in familial ...
Jean-Pierre Rabès, Alain Carrié, Sophie Béliard, Rabes, Jean-Pierre, Beliard, Sophie, Carrie, Alain   +5 more
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The genetics of familial hypercholesterolemia and emerging therapies

, 2015
Anja Vogt Medizinische Klinik und Poliklinik IV, Klinikum der Unversität München, Munich, Germany Abstract: Familial hypercholesterolemia (FH) results in very high levels of atherogenic low-density lipoprotein (LDL) cholesterol from the time ...
Vogt A
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