Results 61 to 70 of about 132,170 (308)

Research on the Effects of Various Intake Levels of Buckwheat on Intestinal Function and Intestinal Flora in Hypercholesterolemic Mice

open access: yesLiang you shipin ke-ji, 2021
The effect of diets containing different proportions of buckwheat on intestinal function of cholesterol absorption and excretion and intestinal microbiota in hypercholesterolemic mice were studied.The mice were divided into four groups where they were ...
TIAN Tian, PEI Xin-li, LIU Hai-ying
doaj   +1 more source

Epidemiology of hypercholesterolemia [PDF]

open access: yesVnitřní lékařství, 2018
Hypercholesterolemia is one of the most important risk factors of cardiovascular (CV) disease. Epidemiology follows the prevalence, the incidence and the possibilities of risk factors or diseases intervention. A review of observation epidemiologic studies, pharmacotherapy and treatment perspectives is presented.
Barbora, Nussbaumerová, Hana, Rosolová
openaire   +2 more sources

Hypercholesterolemia: A disease with expression from childhood

open access: yes, 2013
Hypercholesterolemia results from an alteration, genetic or acquired, in lipoprotein metabolism. Evidence that hypercholesterolemia is associated with the atherosclerotic process from childhood justifies the screening of high-risk children and initiation
Vasconcelos, C.   +5 more
core   +1 more source

Comparative Analysis of Poly(Ethylene Glycol) (PEG) and Poly(2‐Ethyl‐2‐Oxazoline) (PEtOx) for Organic Solvent‐Free Lipid Nanoparticle Formulations

open access: yesAngewandte Chemie International Edition, EarlyView.
Organic solvent‐free lipid nanoparticles featuring PEtOx‐based stealth lipids enable efficient mRNA and CRISPR‐Cas9 delivery while exhibiting markedly improved biocompatibility compared with PEG‐based analogues. Their successful ex vivo and in vivo performance, combined with data‐driven formulation optimization, establishes a versatile platform that ...
Michael Streiber   +21 more
wiley   +1 more source

Engineering Biology Beyond Single Genes: Advances and Challenges in Multiplex Genome Editing

open access: yesAnimal Research and One Health, EarlyView.
Multiplex genome editing is transforming genome engineering from single‐gene perturbation to network‐level control, yet its broader application remains limited by challenges in gRNA array engineering, delivery technologies, and safety management. Emerging AI‐driven approaches are accelerating guide RNA design and CRISPR effector optimization for ...
Linli Wang, Yongbin Liu, Hongbing Han
wiley   +1 more source

Lipoprotein-X: A Case of Falsely Elevated LDL Hypercholesterolemia

open access: yesJACC: Case Reports, 2023
Lipoprotein-X is an extremely rare cause of severe hyperlipidemia. We present a case of a 26-year-old man with primary sclerosing cholangitis who developed lipoprotein X-induced pseudohyponatremia with severe hyponatremia.
Jacob Y. Mok, MD, Jaime Burkle, MD
doaj   +1 more source

EXPERIMENTAL HYPERCHOLESTEROLEMIA [PDF]

open access: yesArchives of Internal Medicine, 1916
n ...
openaire   +2 more sources

ASPECTS OF DETECTING PATIENTS WITH FAMILY HYPERCHOLESTEROLEMIA

open access: yes, 2017
The review presents current data regarding the etiology and epidemiology of familial hypercholesterolemia (FH), algorithms for identifying patients with FH using clinical scales, genetic testing, cascade screening.
N Yu Dranenko   +3 more
core   +1 more source

Posterosuperior and Anterior Rotator Cuff Repairs Yield Comparable 1‐Year Constant Scores in Routine Clinical Practice: A Propensity Score‐Matched Study From LaTour Group

open access: yesArthroscopy, Sports Medicine, and Rehabilitation, EarlyView.
Purpose To compare clinical outcomes and ultrasound‐assessed healing rates between posterosuperior and anterior rotator cuff repairs using propensity score matching. Methods Consecutive patients undergoing rotator cuff repair between 2015 and 2021 by a single fellowship‐trained shoulder surgeon were included if they had posterosuperior or anterior ...
Mustafa S. Rashid   +6 more
wiley   +1 more source

Diabetes Mellitus Is Associated With Increased Risk for Subsequent Hip Arthroscopy After Index Hip Arthroscopy

open access: yesArthroscopy, Sports Medicine, and Rehabilitation, EarlyView.
Purpose To determine whether diabetes mellitus is associated with higher systemic and hip‐specific complications and to evaluate reoperation rates after hip arthroscopy. Methods Using the TriNetX Research Network and Current Procedural Terminology and International Classification of Diseases codes, we identified diabetic and nondiabetic patients aged ...
Nicholas J. Morriss   +3 more
wiley   +1 more source

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