Results 21 to 30 of about 132,170 (308)

Effects of diet-induced hypercholesterolemia and gold nanoparticles treatment on peripheral tissues

Anais da Academia Brasileira de Ciências, 2022
Cholesterol is a lipid molecule of great biological importance to animal cells. Dysregulation of cholesterol metabolism leads to raised blood total cholesterol levels, a clinical condition called hypercholesterolemia.
MATHEUS S. RODRIGUES, JULIA N. MARTINS, GABRIELA C. DE PAULA, LIGIA M. VENTURINI, GUSTAVO DE B. SILVEIRA, EMÍLIO L. STRECK, JOSIANI BUDNI, RICARDO A. MACHADO DE ÁVILA, ANDREZA F. DE BEM, PAULO C.L. SILVEIRA, JADE DE OLIVEIRA   +10 more
doaj   +1 more source

A comprehensive metabolic profiling of the metabolically healthy obesity phenotype

Lipids in Health and Disease, 2020
Background The ever-increasing prevalence of obesity constitutes a major health problem worldwide. A subgroup of obese individuals has been described as “metabolically healthy obese” (MHO).
Vibeke H. Telle-Hansen, Jacob J. Christensen, Gulla Aase Formo, Kirsten B. Holven, Stine M. Ulven   +4 more
doaj   +1 more source

Web-Based Tool (FH Family Share) to Increase Uptake of Cascade Testing for Familial Hypercholesterolemia: Development and Evaluation

JMIR Human Factors, 2022
BackgroundFamilial hypercholesterolemia, a prevalent genetic disorder, remains significantly underdiagnosed in the United States.
Hana Bangash, Ahmed Makkawy, Justin H Gundelach, Alexandra A Miller, Kimberly A Jacobson, Iftikhar J Kullo   +5 more
doaj   +1 more source

Adverse outcome pathway for pregnane X receptor-induced hypercholesterolemia [PDF]

, 2023
Pharmaceuticals and environmental contaminants contribute to hypercholesterolemia. Several chemicals known to cause hypercholesterolemia, activate pregnane X receptor (PXR).
Itkonen, Anna, Jaana Rysä, Anna Itkonen, Jukka Hakkola, Hakkola, Jukka, Rysä, Jaana   +5 more
core   +1 more source

Precision screening for familial hypercholesterolaemia: a machine learning study applied to electronic health encounter data

The Lancet: Digital Health, 2019
Summary: Background: Cardiovascular outcomes for people with familial hypercholesterolaemia can be improved with diagnosis and medical management. However, 90% of individuals with familial hypercholesterolaemia remain undiagnosed in the USA. We aimed to
Kelly D Myers, BS, Joshua W Knowles, MD, David Staszak, PhD, Michael D Shapiro, DO, William Howard, PhD, Mrinal Yadava, MD, David Zuzick, MBA, Latoya Williamson, MS, Nigam H Shah, PhD, Juan M Banda, PhD, Joe Leader, BS, William C Cromwell, MD, Ed Trautman, PhD, Michael F Murray, ProfMD, Seth J Baum, MD, Seth Myers, PhD, Samuel S Gidding, MD, Katherine Wilemon, BS, Daniel J Rader, ProfMD   +18 more
doaj   +1 more source

Education on Prevention of Hypercholesterolemia and Hypertension by Consuming Sardeljondan Herbal Drinks

Jurnal Soeropati, 2022
Hypertension is a condition in which a person experiences an increase in systolic blood pressure of more or equal to 140 mmHg and diastolic blood pressure of more or equal to 90 mmHg.
Yauwan Tobing Lukiyono, Abraham Ahmad Ali Firdaus, Salfa Salsabilah Zain, Anis Hanifa Rahmawati, Nur Zulviah   +4 more
doaj   +1 more source

How do index patients participating in genetic screening programmes for familial hypercholesterolemia (FH) interpret their DNA results?:A UK-based qualitative interview study [PDF]

, 2011
OBJECTIVE: To explore patients' interpretations of their DNA results for familial hypercholesterolemia (FH). METHODS: In-depth interviews were conducted with patients from two lipid clinics in Scotland, who were offered genetic testing as part of a ...
Jenkins, Nick, Lawton, Julia, Douglas, Margaret, Walker, Simon, Hallowell, Nina, Finnie, Robert, Porteous, Mary   +6 more
core   +1 more source

Hypercholesterolemia [PDF]

, 2015
This book is aimed to accentuate the importance of hypercholesterolemia, since targeting and treating the hypercholesterolemia is increasingly well known as an essential strategy in the prevention of atherosclerosis-induced cardiovascular disease.

core   +1 more source

Identifying endemic areas and estimating the prevalence of hyperlipidemia in Taiwan's townships

Journal of the Formosan Medical Association, 2021
Background/Purpose: This study aimed to evaluate geographic variations and differences in the prevalence of hypertriglyceridemia and hypercholesterolemia between Taiwan's townships. Methods: The prevalence of hypertriglyceridemia and hypercholesterolemia
Cheng-Feng Tsao, Chih-Min Chang, Shao-Wen Weng, Pei-Wen Wang, Chih-Yun Lin, Sheng-Nan Lu   +5 more
doaj   +1 more source

Phase Ib study of anlotinib combined with TQB2450 in pretreated advanced biliary tract cancer and biomarker analysis

Hepatology, EarlyView., 2022
Phase 1b study of anlotinib combined with TQB2450 in pretreated advanced biliary tract cancer and biomarker analysis. Abstract Background and Aims We evaluated the efficacy and safety of the antiangiogenic tyrosine kinase inhibitor anlotinib plus TQB2450, a programmed death‐ligand 1 inhibitor in pretreated advanced biliary tract cancers (BTCs ...
Jun Zhou, Yongkun Sun, Wen Zhang, Jiajia Yuan, Zhi Peng, Wei Wang, Jifang Gong, Lin Yang, Yanshuo Cao, Hong Zhao, Chao Chen, Weifeng Wang, Lin Shen, Aiping Zhou   +13 more
wiley   +1 more source