Results 21 to 30 of about 182,037 (304)

Identifying endemic areas and estimating the prevalence of hyperlipidemia in Taiwan's townships

Journal of the Formosan Medical Association, 2021
Background/Purpose: This study aimed to evaluate geographic variations and differences in the prevalence of hypertriglyceridemia and hypercholesterolemia between Taiwan's townships. Methods: The prevalence of hypertriglyceridemia and hypercholesterolemia
Cheng-Feng Tsao, Chih-Min Chang, Shao-Wen Weng, Pei-Wen Wang, Chih-Yun Lin, Sheng-Nan Lu   +5 more
doaj   +1 more source

New approaches in detection and treatment of familial hypercholesterolemia [PDF]

, 2015
Familial hypercholesterolemia (FH) is an autosomal dominant genetic disorder that clinically leads to increased low density lipoprotein-cholesterol (LDL-C) levels. As a consequence, FH patients are at high risk for cardiovascular disease (CVD). Mutations
Hartgers, ML, Hovingh, GK, Ray, KK
core   +3 more sources

Socioeconomic inequalities of hypercholesterolemia in Kurdistan Province, Iran, in 2005

Chronic Diseases Journal, 2015
BACKGROUND: Hypercholesterolemia is one of the main risk factors for many non-communicable diseases (NCDs). Many deaths caused by hypercholesterolemia usually occur in low and middle income countries.
Fatemeh Gholami, Ghobad Moradi
doaj   +1 more source

Systematic review and network meta-analysis on the efficacy of evolocumab and other therapies for the management of lipid levels in hyperlipidemia [PDF]

, 2017
Background: The proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors evolocumab and alirocumab substantially reduce low‐density lipoprotein cholesterol (LDL‐C) when added to statin therapy in patients who need additional LDL‐C reduction ...
Bray, Sarah, Bridges, Ian, Cheng, Lung-I, Dent, Ricardo, Deshpande, Sohan, Forbes, Carol A., Gandra, Shravanthi R., Kleijnen, Jos, Ross, Janine, Sattar, Naveed, Stroes, Erik S.G., Toth, Peter P., Worth, Gavin M., Worthy, Gillian   +13 more
core   +1 more source

Evaluation of the Frequency of Familial Hypercholesterolemia: A Single-Center Experience

Endocrinology Research and Practice, 2019
Objective: Familial hypercholesterolemia is an autosomal dominant disease associated with elevated low-density lipoprotein cholesterol and increased premature atherosclerosis.
Mehmet Ali EREN, Ataman GÖNEL, İsmail KOYUNCU, Ahmet Cebeli GÖKAY, Tevfik SABUNCU   +4 more
doaj   +1 more source

Prevention of High-Fat Diet-Induced Hypercholesterolemia by Lactobacillus reuteri Fn041 Through Promoting Cholesterol and Bile Salt Excretion and Intestinal Mucosal Barrier Functions

Frontiers in Nutrition, 2022
Objectives:Lactobacillus reuteri Fn041 (Fn041) is a probiotic isolated from immunoglobulin A coated microbiota in the human breast milk of Gannan in China with a low incidence of hypercholesterolemia.
Mengyao Lu, Jin Sun, Yuning Zhao, Haowen Zhang, Xinyue Li, Jingbo Zhou, Hongyang Dang, Jidong Zhang, Wenjing Huang, Ce Qi, Duo Li   +10 more
doaj   +1 more source

Ezetimibe therapy: mechanism of action and clinical update. [PDF]

, 2012
The lowering of low-density lipoprotein cholesterol (LDL-C) is the primary target of therapy in the primary and secondary prevention of cardiovascular events.
Dayspring, Thomas D, Phan, Binh An P, Toth, Peter P   +2 more
core   +1 more source

Treatment and follow-up of coronary artery disease in a child with homozygous familial hypercholesterolemia

Medicine Science, 2022
Familial hypercholesterolemia is a metabolic disease caused by a mutation in the low-density lipoprotein receptor gene. It carries early atherosclerosis and coronary artery disease risks.
Mehmet Oncul, Cemsit Karakurt, Ozlem Elkiran, Aysehan Akinci, Nevzat Erdil   +4 more
doaj   +1 more source

Phase Ib study of anlotinib combined with TQB2450 in pretreated advanced biliary tract cancer and biomarker analysis

Hepatology, EarlyView., 2022
Phase 1b study of anlotinib combined with TQB2450 in pretreated advanced biliary tract cancer and biomarker analysis. Abstract Background and Aims We evaluated the efficacy and safety of the antiangiogenic tyrosine kinase inhibitor anlotinib plus TQB2450, a programmed death‐ligand 1 inhibitor in pretreated advanced biliary tract cancers (BTCs ...
Jun Zhou, Yongkun Sun, Wen Zhang, Jiajia Yuan, Zhi Peng, Wei Wang, Jifang Gong, Lin Yang, Yanshuo Cao, Hong Zhao, Chao Chen, Weifeng Wang, Lin Shen, Aiping Zhou   +13 more
wiley   +1 more source

Familial hypercholesterolemia: a systematic review of guidelines on genetic testing and patient management [PDF]

, 2017
BACKGROUND: Familial hypercholesterolemia (FH) is an autosomal-dominant hereditary disorder of lipid metabolism that causes lifelong exposure to increased LDL levels resulting in premature coronary heart disease and, if untreated, death.
Baccolini, Valentina, D'Andrea, Elvira, De Vito, Corrado, Massimi, Azzurra, Migliara, Giuseppe, Rosso, Annalisa, Villari, Paolo   +6 more
core   +2 more sources