Results 271 to 280 of about 19,107 (290)

Association of Glucagon‐Like Peptide‐1 Receptor Agonists With Cancer Risk in Older Adults With Type 2 Diabetes

Obesity, EarlyView.
ABSTRACT Objective The real‐world evidence on the association between glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs) and cancer risk remains limited and mixed. Methods In 2013–2020 national Medicare claims data, we included cancer‐naïve patients with type 2 diabetes (T2D). We identified those who initiated GLP‐1 RA, sodium‐glucose cotransporter 2
Ying Lu, Hao Dai, Huilin Tang, William T. Donahoo, Thomas J. George, Ramon C. Sun, Sizun Jiang, Aik Choon Tan, Yi Guo, Jonathan D. Licht, John M. Allen, Kelvin P. Lee, Jingchuan Guo, Jiang Bian   +13 more
wiley   +1 more source

Dyslipidemia Assessed in Pediatric Patients: Validation of LDL-C Assessed by Friedewald Formula, Direct Assessment, and Sampson-NIH Formula. [PDF]

Diagnostics (Basel)
Wawer J, Chojęta A, Swadźba J, Janiszewska M, Chojęta M, Wawer GA, Grywalska E, Milaniuk A.   +7 more
europepmc   +1 more source

Weekly Subcutaneous VK2735, a GIP/GLP‐1 Receptor Dual Agonist, for Weight Management: Phase 2, Randomized, 13‐Week VENTURE Study

Obesity, EarlyView.
Four doses of VK2735 and a placebo group were included in the VENTURE study. Adults who were overweight or had obesity had significant weight loss when taking any dose of VK2735 for 13 weeks. More people lost at least 10% of their body weight as the dose increased.
Harold E. Bays, Phillip Toth, Naim Alkhouri, John Pullman, Bradley Freilich, Joel Neutel, Summer Ji, Scott Stubbe, Parke Hedges, Brian Lian   +9 more
wiley   +1 more source

Circulating Profiles of the Bile Acid Metabolomics in Patients With Polycystic Ovary Syndrome Treated With Metformin or Canagliflozin

Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, EarlyView.
ABSTRACT Objective Bile acids are indispensable modulators in the development of polycystic ovary syndrome (PCOS). Our previous study identified that metformin and canagliflozin have similar efficacy in patients with PCOS combined with insulin resistance (IR).
Qi Yan, Meili Cai, Nan Wang, Wenhao Wu, Hua Zhang, Yikun Zhu, Jing Luo, Manna Zhang, Jin Li   +8 more
wiley   +1 more source

Development of a predictive model for severe hyperlipidemic acute pancreatitis based on LASSO regression: a retrospective study. [PDF]

PeerJ
Zhang Q, Han R, Li Z, Yan K, Dai X, Yu G.   +5 more
europepmc   +1 more source

Pre‐Existing Nocturia Status Predicts Bladder Symptom Exacerbation Following COVID‐19 Vaccination in Women

The Kaohsiung Journal of Medical Sciences, EarlyView.
Hsien‐Che Ou, Hao‐Wei Chen, Yung‐Shun Juan, Yu‐Chen Chen   +3 more
wiley   +1 more source

Coupling CZE, Liquid‐Phase Ion Mobility, to MS/MS for Quantitative Top‐Down Proteomics: Revealing Significant Proteoform Differences Between Healthy and Alzheimer's Disease Brains

PROTEOMICS, EarlyView.
ABSTRACT Alzheimer's disease (AD) is a neurodegenerative disorder characterized by cognitive decline and pathological protein aggregation. Comprehensive quantitative proteomics of brain tissues from AD patients is critical for pursuing a better understanding of the molecular mechanisms that drive AD progression.
Mehrdad Falamarzi Askarani, Fei Fang, Scott E. Counts, Liangliang Sun   +3 more
wiley   +1 more source

Cardiovascular Risk Factor Management in Medicare Advantage and Traditional Medicare. [PDF]

Circ Cardiovasc Qual Outcomes
Oseran AS, Aggarwal R, Wadhera RK.
europepmc   +1 more source

Advancing Extracellular Vesicle Research: A Review of Systems Biology and Multiomics Perspectives

PROTEOMICS, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are membrane‐bound vesicles secreted by various cell types into the extracellular space and play a role in intercellular communication. Their molecular cargo varies depending on the cell of origin and its functional state.
Gloria Kemunto, Samaneh Ghadami, Kristen Dellinger   +2 more
wiley   +1 more source

Tubular Adenoma Arising Within a Rectosigmoid Xanthoma: A Case Report. [PDF]

Cureus
Coffey K, Mateja HL, Bowers W, DeVito P.
europepmc   +1 more source