Results 71 to 80 of about 19,107 (290)

Seipin‐Mediated Lipid Droplet Formation in Cardiomyocytes Ameliorates Cardiac Ischemia/Reperfusion Injury

Advanced Science, EarlyView.
Lipid droplets (LDs) protect the heart against lipotoxicity in cardiac ischemia/reperfusion (I/R) injury; however, they are insufficient to prevent cardiomyocyte death. Seipin plays a central role in the insufficient formation of LDs, subsequent lipotoxicity, and myocardial injury during cardiac I/R injury.
Changyun Liu, Junxia Zhang, Yusi Chen, Geng Shen, Yufei Han, Zihao Zhou, Jinxuan Chen, Xuya Kang, Huilin Qu, Jiaxin Duanmu, Haibao Shang, Yingjia Li, Wei Huang, Yan Zhang   +13 more
wiley   +1 more source

Factors Associated with Goal Achievement in Patients with Dyslipidemia in Primary Care

Iatreia
Introduction: Dyslipidemia promotes atherosclerotic disease. A strategy to reduce this risk is to achieve low-density lipoprotein (LDL) goals; however, these are often not attained.
Pinto-González, Gustavo, Uribe-Velez, Natalia Andrea , Quirós-Gómez, Oscar Iván   +2 more
doaj   +1 more source

Perfil nutricional e cardiovascular de ratos normotensos e hipertensos sob dieta hiperlipídica Perfil nutricional y cardiovascular de ratas normotensas e hipertensos bajo dieta hiperlipídica Nutritional and cardiovascular profiles of normotensive and hypertensive rats kept on a high fat diet

Arquivos Brasileiros de Cardiologia, 2009
FUNDAMENTO: Embora dietas hiperlipídicas (DH) promovam distúrbios nutricionais e cardíacos, poucos estudos avaliaram sua influência em ratos normotensos Wistar-Kyoto (WKY) e espontaneamente hipertensos (SHR).
Silvio A. Oliveira Júnior, Katashi Okoshi, Ana Paula Lima-Leopoldo, André S. Leopoldo, Dijon H.S. Campos, Paula F. Martinez, Marina P. Okoshi, Carlos R. Padovani, Maeli Dal Pai-Silva, Antonio C. Cicogna   +9 more
doaj   +1 more source

Cardiovascular Risk Factors Research in Bosnia and Herzegovina [PDF]

, 2009
This study describes the current situation of cardiovascular risk factors research in the Bosnia and Herzegovina, with special emphasis on the Herzegovina region.
Aida Pilav, Boris Maslov, Ivan Vasilj, Ozren Polašek   +3 more
core   +1 more source

Tailored Information and Automated Reminding to Improve Medication Adherence in Spanish- and English-Speaking Elders Treated for Memory Impairment. [PDF]

, 2012
Medication adherence is recognized as an issue of critical importance within health care, as many patients do not take their medications as prescribed.
Czaja, Sara J, Hertzog, Christopher, Ownby, Raymond L   +2 more
core   +1 more source

Lipid‐Driven OLR1/FOXM1/FGF19 Axis Orchestrates Crosstalk in an Epithelial‐Fibroblast Positive Feedback Promoting Progesterone Resistance in Endometrial Cancer

Advanced Science, EarlyView.
It is revealed that a metabolic–stromal loop driven by oxLDL–OLR1–FOXM1–FGF19 signaling promotes progesterone resistance in endometrial cancer. OxLDL activates epithelial–fibroblast crosstalk, enhancing proliferation and hormonal insensitivity. Disruption of this circuit, especially with resveratrol, restores MPA sensitivity, highlighting a potential ...
Xingchen Li, Yue Qi, Yuman Wu, Xinyi Bi, Yiqin Wang, Jiaqi Wang, Jingyuan Wang, Lingpu Zhang, Haihua Xiao, Jianliu Wang   +9 more
wiley   +1 more source

Comparison of the anthropometric and biochemical variables between children and their parents

Archivos Latinoamericanos de Nutrición, 2007
The objective of this study was to compare the anthropometry, body composition and biochemical profile between eutrophic and obese children, as well as to relate the children’s nutritional state and body composition to those of their respective parents ...
Juliana Farias de Novaes, Sylvia do Carmo Castro Franceschini, Sílvia Eloiza Priore   +2 more
doaj  

Statin-Associated Muscle Adverse Events : Update for clinicians

Sultan Qaboos University Medical Journal, 2016
Statins are potent medications which reduce low-density lipoprotein cholesterol (LDL-C) levels. Their efficacy in cardiovascular risk reduction is well established and indications for their use are expanding.
Maha A. Al-Mohaissen, Martha J. Ignaszewski, Jiri Frohlich, Andrew P. Ignaszewski   +3 more
doaj   +1 more source

Microglial Fkbp5 Impairs Post‐Stroke Vascular Integrity and Regeneration by Promoting Yap1‐Mediated Glycolysis and Oxidative Phosphorylation

Advanced Science, EarlyView.
A post‐stroke perivascular niche of microglia characterized by low expression of M2 markers and elevated glycolysis, oxidative phosphorylation (OXPHOS), and phagocytic activity is identified, which is termed stroke‐activated vascular‐associated microglia (stroke‐VAM).
Yanan Li, Yanmei Qiu, Yunlei Yang, Yanhao Wei, Haokun Peng, Longhai Zeng, Pengcheng Li, Rentang Bi, Bo Hu   +8 more
wiley   +1 more source

Effectiveness of Pre‐Transplant Dual GLP‐1 Receptor Agonist and SGLT2 Inhibitor Therapy on All‐Cause Mortality in Organ Transplantation Candidates with Obesity and Type 2 Diabetes: a Target‐Trial Emulation

Advanced Science, EarlyView.
This target trial emulation in solid organ transplant candidates with obesity and type 2 diabetes evaluates whether pre‐transplant dual therapy with GLP‐1 receptor agonists plus SGLT2 inhibitors is associated with post‐transplant mortality and kidney graft outcomes compared with monotherapy or usual care, using multinational electronic health records ...
Yu‐Nan Huang, Min‐Yu Tsou, Pin‐Hung Li, Jo‐Ching Chen, Yen‐Liang Liu, Gideon Meyerowitz‐Katz, Tsung‐Hsun Tsai, Pen‐Hua Su   +7 more
wiley   +1 more source