Results 71 to 80 of about 70,417 (342)

Risk reduction and the program on the surgical control of the hyperlipidemias.

Circulation, 2001
Control of the Hyperlipidemias To the Editor: I write on behalf of the 838 patients in the Program on the Surgical Control of the Hyperlipidemias (POSCH) trial; its principal investigators; and the members of the POSCH Data Monitoring Committee ...
Henry Buchwald
semanticscholar   +1 more source

Metabolomic and Cellular Mechanisms of Drug‐Induced Ototoxicity and Nephrotoxicity: Therapeutic Implications of Uric Acid Modulation

Advanced Science, EarlyView.
Drug‐induced renal damage impairs uric acid excretion, causing its accumulation in the serum, which subsequently infiltrates the cochlea. Xanthine oxidase and the ABCG2 transporter, critical in uric acid metabolism and excretion, undergo pathological changes in renal tubular and cochlear stria vascularis cells.
Suhan Guo, Cheng Cheng, Yunhao Wu, Kaidi Shen, Depeng Zhang, Bin Chen, Xinyu Wang, Luping Shen, Qixiang Zhang, Renjie Chai, Guangji Wang, Fang Zhou   +11 more
wiley   +1 more source

Characterization of ultrasonically extracted flaxseed polysaccharide gum and assessing its lipid‐lowering potential in a rat model

Food Science &Nutrition, Volume 11, Issue 1, Page 137-147, January 2023., 2023
On the basis of current research it was suggested that FPG have anti‐hyperlipidemic potential. Still, the mechanism of actions of FPG as anti‐hyperlipidemic and other therapeutic potential have yet to be explored. Abstract Flaxseed polysaccharide gum (FPG) was extracted through the ultrasound‐assisted process using water as a solvent with a yield ...
Muhammad Nadeem Akhtar, Anees Ahmed Khalil, Ahmed Bilal, Muhammad Afzaal, Tabussam Tufail, Rabia Saeed, Rabia Siddique, Arash Nemat, Muhammad Faisal Manzoor   +8 more
wiley   +1 more source

Asprosin‐FABP5 Interaction Modulates Mitochondrial Fatty Acid Oxidation through PPARα Contributing to MASLD Development

Advanced Science, EarlyView.
Aided by FABP5, abnormally elevated asprosin in hepatocytes enters the nucleus, targets and inhibits PPARα binding to the CPT1A promoter, thereby suppressing FAO. Circulating asprosin exacerbates insulin resistance, collectively driving MASLD progression.
Yuan‐Yuan Yu, Min Feng, Yi Chen, Hong‐Lin Jia, Qi Zhang, Ming Tong, Yan‐Xi Li, Yu Zhao, Xin‐Xin Liu, Shi‐Feng Cao, Zheng‐kai Wang, Hou‐wei Li, Xue Liu, Yan Zhang   +13 more
wiley   +1 more source

Study on the hypolipidemic effect of Inonotus obliquus polysaccharide in hyperlipidemia rats based on the regulation of intestinal flora

Food Science &Nutrition, Volume 11, Issue 1, Page 191-203, January 2023., 2023
The IOP‐A has a hypolipidemic effect, which may be due to its ability to regulate the expression of CYP7A1 and SREBP‐1c, as well as to correct an imbalance in the structure of the intestinal microflora. Abstract The purpose of this study was to observe the effect of Inonotus obliquus polysaccharide (IOP) on blood lipids and its regulation on the ...
Fengyuan Lin, Xiao Li, Xiao Guo, Xuechun Lu, Xiao Han, GuangYu Xu, Peige Du, Liping An   +7 more
wiley   +1 more source

Macrophage WEE1 Directly Binds to and Phosphorylates NF‐κB p65 Subunit to Induce Inflammatory Response and Drive Atherosclerosis

Advanced Science, EarlyView.
The present study shows that macrophage WEE1 drives NF‐κB activation and inflammatory atherosclerosis by directly phosphorylating p65 at S536. This finding illustrates a macrophage‐specific WEE1‐p65 axis in regulating inflammatory atherosclerosis and points out new directions to broaden the clinical applications for WEE1 inhibitors in atherosclerosis ...
Zhuqi Huang, Sirui Shen, Weixin Li, Mengyang Wang, Yudie Yang, Wu Luo, Xue Han, Zheng Xu, Julian Min, Xiaohong Long, Weijian Huang, Gaojun Wu, Yi Wang, Guang Liang   +13 more
wiley   +1 more source

Chemical composition of kabuli and desi chickpea (Cicer arietinum L.) cultivars grown in Xinjiang, China

Food Science &Nutrition, Volume 11, Issue 1, Page 236-248, January 2023., 2023
Chemical compositions such as protein, fat, ash, moisture, starch, vitamin B1 and mineral, as well as amino acids and fatty acids were determined in kabuli and desi chickpea species. Forty‐six types of flavonoids in Muying‐1 chickpea were analyzed with UPLC‐QqQ‐MS method.
Shiqi Xiao, Zhenglei Li, Keqiang Zhou, Yinghua Fu   +3 more
wiley   +1 more source

Correlation Between Blood Glucose Level and Cerebral Small Vessel Disease Markers in Neurologically Asymptomatic, Nondiabetic Individuals

AGING MEDICINE, EarlyView.
The prevalence of neurologically asymptomatic CSVD is common in the nondiabetic population. Glycated hemoglobin A1c correlated with periventricular white matter hyperintensities. Fasting blood glucose was associated with deep cerebral microbleeds. Better control of blood glucose may have a beneficial effect on reducing the risk of CSVD.
Xinxin Ma, Fang Liu, Lei Qiu, Juan Chen, Wei Du, Jing He, Aizhen Sheng, Yinhong Liu   +7 more
wiley   +1 more source

Long‐term use of probiotics for the management of office and ambulatory blood pressure: A systematic review and meta‐analysis of randomized, controlled trials

Food Science &Nutrition, Volume 11, Issue 1, Page 101-113, January 2023., 2023
Long‐term probiotics' consumption (≥8 weeks) had a beneficial effect on office and ambulatory blood pressure (BP), especially in the diabetes and hypertension, and the changes in BP were not associated with the increase of age, body mass index (BMI), and treatment duration.
Tian‐Xue Zhao, Li Zhang, Ning Zhou, Dong‐Sheng Sun, Jian‐Hong Xie, Shao‐Kun Xu   +5 more
wiley   +1 more source

Lactobacillus paracasei N1115 attenuates obesity in high‐fat diet‐induced obese mice

Food Science &Nutrition, Volume 11, Issue 1, Page 418-427, January 2023., 2023
Lactobacillus paracasei N1115 relieved high fat diet induced obesity. Lactobacillus paracasei N1115 decreased body weight, fat accumulation and hyperlipidemia by increasing the abundance of beneficial bacteria (Allobaculum and L. Zeae) and decreased harmful bacteria (Turicibacter).
Yanan Sun, Shanbin Chen, Fazheng Ren, Yixuan Li   +3 more
wiley   +1 more source