Results 71 to 80 of about 1,081,004 (187)

P37 Hypermobile ehlers-danlos syndrome explosion in the UK!! [PDF]

Abstracts, 2019
Background Ehlers-Danlos Syndrome (EDS) is a heterogeneous group of collagen disorders. There is controversy regarding clinical diagnosis of hypermobility EDS. The Beighton score and the recent international classification of EDS are not validated in children. Clinicians get the impression that there is a substantial increase in frequency of referrals
Fatemeh Jenabi, Alice Leahy, Nicola Foulds, Hans de Graaf   +3 more
openaire   +1 more source

Could the Phenotypic Outcomes of Genetic Variability in Cells Operating in Mechanically Dynamic Environments be Influenced by a Disrupted “Cell‐ECM” Relationship? Using Cystic Fibrosis and Marfan Syndrome as an Example

BioEssays, Volume 48, Issue 4, April 2026.
The “Cell‐Extracellular Matrix Unit” in a mechanically active environment (Centre). Mutations in ECM molecules such as fibrillin‐1 can lead to Marfan Syndrome (A), while mutations in the cellular CFTR can lead to Cystic Fibrosis (B). A combination of such mutations without a clinical phenotype alone could also lead to disease (C). ABSTRACT Diseases due
David A. Hart
wiley   +1 more source

The Extracellular Matrix Across States: From Homeostasis to Dysfunction in Rare Connective Tissue Disorders

Proteoglycan Research, Volume 4, Issue 2, April 2026.
ABSTRACT The extracellular matrix (ECM) provides a dynamic environment in which the fine balance between biosynthesis, degradation and/or maturation of matrix components critically governs its structure and function. It is well established that the ECM plays a central role not only in the physiological functions of tissues, but also in the pathogenesis
Roméo M. Diana, Sandrine Gulberti, Catherine Bui   +2 more
wiley   +1 more source

Association Between Changes in Shoulder Strength and Self‐Reported Shoulder Symptoms in Patients With Hypermobility Following 16‐Weeks of High‐Load or Low‐Load Exercise: A Secondary Analysis of an RCT

Physiotherapy Research International, Volume 31, Issue 2, April 2026.
ABSTRACT Background and Purpose Hypermobility Spectrum Disorder (HSD) is a common musculoskeletal condition that impairs function and quality of life. While exercise therapy has shown to improve outcomes, treatment standardisation is lacking and the relationship between strength and symptoms remains unclear.
Thomas Christensen, Carsten Bogh Juhl, Birgit Juul‐Kristensen, Søren T. Skou, Jens Søndergaard, Karen Søgaard, Behnam Liaghat   +6 more
wiley   +1 more source

Hypermobile Ehlers-Danlos syndrome and rehabilitation: taking stock of evidence based medicine: a systematic review of the literature [PDF]

, 2018
[Purpose] The aim of the study was to conduct a systematic review about rehabilitation treatment of hypermobile Ehlers-Danlos syndrome, according to Evidence Based Medicine.
Gianluca Ciardi, Bruno Corrado
core   +1 more source

Gastrointestinal Symptoms and Systemic Comorbidities in Patients With POTS: A Systematic Review and Meta‐Analysis

Neurogastroenterology &Motility, Volume 38, Issue 4, April 2026.
This meta‐analysis reveals that a significant proportion of patients with POTS experience gastrointestinal symptoms. The most prevalent symptoms include nausea, bloating, abdominal pain, and postprandial fullness. There is a notable overlap of POTS with IBS, joint hypermobility, mast cell activation syndrome, and chronic fatigue.
Dmitrii Kulin, Ayesha Shah, Thomas Fairlie, Kyle Staller, Samuel Nurko, Laurie Keefer, Qasim Aziz, Douglas A. Drossman, Michael P. Jones, Gerald Holtmann   +9 more
wiley   +1 more source

Absence of the inferior labial and lingual frenula in Ehlers-Danlos syndrome

, 2001
The diagnosis of Ehlers-Danlos syndrome Is based on distinctive phenotypical characteristics such as hyperelastic skin and hypermobile joints. To date, no congenital physical markers exist for Identifying patients with Ehlers-Danlos syndrome.
DI MAGGIO, G., Franco Bagnoli, PARRINI, S., Giovanni Di Maggio, Paolo Toti, Claudio De Felice, BAGNOLI, F., Stefano Parrini, TOTI, P., DE FELICE, C.   +9 more
core   +1 more source

Joint Pain Outcomes After Metabolic and Bariatric Surgery in Patients With and Without Hypermobility

Obesity Science &Practice, Volume 12, Issue 1, February 2026.
ABSTRACT Objective Obesity increases the risk of musculoskeletal conditions, but retrospective studies have suggested that individuals with joint hypermobility experience more joint pain after metabolic and bariatric surgery and weight loss. Joint hypermobility is the ability of one or more joints to move beyond the normal range of motion.
Elke Schubert‐Hjalmarsson, Lizette Albertsson, Ebba Englund, Monika Fagevik Olsén   +3 more
wiley   +1 more source

A Roadmap for Advancing Women's Health in Disorders of the Gut‐Brain Interaction

United European Gastroenterology Journal, Volume 14, Issue 1, February 2026.
ABSTRACT Disorders of the Gut‐Brain Interaction (DGBI) are highly prevalent conditions that all gastroenterologists encounter in clinical practice. Differences between men and women in the prevalence and symptom burden of DGBI have been well documented in numerous epidemiological and observational studies.
Madison R. Heath, Yuying Luo
wiley   +1 more source

Supplemental Material - The role of functional disability and social support in psychological outcomes for individuals with pediatric hypermobile ehlers–danlos syndrome

, 2022
Supplemental Material for The role of functional disability and social support in psychological outcomes for individuals with pediatric hypermobile ehlers–danlos syndrome by Keely H Bieniak, Brad T Tinkle, Susan T Tran in Journal of Child Health ...
Brad T Tinkle (14242514), Keely H Bieniak (14242511), Susan T Tran (14242517)   +2 more
core   +1 more source