Results 11 to 20 of about 10,272 (165)

Adipsic Hypernatremia Complicated by Hyperosmolar Hyperglycemic State and Extensive Venous Thromboembolism After Traumatic Brain Injury: A Case Report [PDF]

open access: yesClinical Case Reports, Volume 14, Issue 11, November 2026.
ABSTRACTAdipsic hypernatremia is a rare disorder characterized by impaired thirst perception despite severe hyperosmolality, most commonly resulting from hypothalamic dysfunction. Hyperosmolar hyperglycemic state (HHS) may further aggravate dehydration and electrolyte imbalance, increasing the risk of neurologic injury, acute kidney injury (AKI), and ...
Mahshad Ghoddusi   +6 more
wiley   +2 more sources

Diagnosis and Treatment of Brain Injury Complicated by Hypernatremia

open access: yesFrontiers in Neurology, 2022
Hypernatremia is a common electrolyte disorder in patients with brain injury. The mortality of brain injury patients with severe hypernatremia may be as high as 86.8%. The efficacy of conventional treatment for hypernatremia is limited.
Shiren Sun, Ming Bai
exaly   +3 more sources

Progression to Severe Hypernatremia in Hospitalized General Medicine Inpatients: An Observational Study of Hospital-Acquired Hypernatremia

open access: yesMedicina (Lithuania), 2020
Background and objectives: Hypernatremia can be community or hospital-acquired, and there may be specific factors unique to the hospital environment, such as intravenous fluid treatment, which contribute to hypernatremia.
Andy K H Lim
exaly   +3 more sources

Understanding Hypernatremia [PDF]

open access: yesAmerican Journal of Nephrology, 2012
Understanding hypernatremia is at times difficult for many clinicians. However, hypernatremia can often be deciphered easily with some basic understanding of water and sodium balance. Here, the basic pathophysiological abnormalities underlying the development of sodium disorders are reviewed, and case examples are given.
Ramin Sam, Iraj Feizi
exaly   +3 more sources

Extracellular ionic concentration modulates arrhythmias in a simulated population of human ventricular myocytes with long QT syndrome type 3 [PDF]

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Schematic illustrating the in silico study pipeline. A total of 50,000 virtual myocytes were generated, which were then filtered to 7093 myocytes that fit experimentally constrained biomarkers for physiological electrical and calcium behaviour under wild‐type conditions.
Katherine Flannery   +3 more
wiley   +2 more sources

Hypernatremia during the first week of life in very preterm infants and neurodevelopmental outcomes at 3 to 4 years of age: a cohort study [PDF]

open access: yesBMC Pediatrics
Background Hypernatremia is a common electrolyte disorder in both term and preterm infants. Previous studies have suggested a correlation between hypernatremia and short-term complications in preterm infants, such as intraventricular hemorrhage and ...
Michiko Murakami   +6 more
doaj   +2 more sources

Hypernatremia [PDF]

open access: yesClinical Journal of the American Society of Nephrology, 2019
Hypernatremia is an electrolyte disorder most prevalent in the elderly and the critically ill, with over 60% of cases developing over the course of an inpatient stay. Characterized by elevated serum sodium concentrations, this disorder is manifested either by pure-water loss without replacement, or excessive sodium intake without appropriate water ...
Jessica S. Everitt   +2 more
  +6 more sources

Association of Hypernatremia with Immune Profiles and Clinical Outcomes in Adult Intensive Care Unit Patients with Sepsis

open access: yesBiomedicines, 2022
Both hypernatremia and an abnormal immune response may increase hospital mortality in patients with sepsis. This study examined the association of hypernatremia with abnormal immune response and mortality in 520 adult patients with sepsis in an intensive
Chiung-Yu Lin   +9 more
doaj   +1 more source

Anesthetic care of a child with severe hypernatremia [PDF]

open access: yesPediatric Anesthesia and Critical Care Journal (PACCJ), 2021
Severe electrolyte derangements are routinely corrected prior to elective anesthetic care. However, in urgent and emergent situations, anesthetic care may be required even with electrolyte disorders.
S. Lozovskiy, J. D. Tobias
doaj   +1 more source

Hypernatremia in Newborns: A Practical Approach to Management

open access: yesBiomedicine Hub, 2022
Hypernatremia is a potentially serious condition in both term and preterm babies, which can lead to severe and permanent neurological damage. There are many physiological changes in sodium homeostasis that occur soon after birth.
Naveed Ur Rehman Durrani   +2 more
doaj   +1 more source

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