Results 21 to 30 of about 74,450 (239)
The calcium-sensing receptor as a regulator of cellular fate in normal and pathological conditions [PDF]
, 2013 The calcium-sensing receptor (CaSR) belongs to the evolutionarily conserved family of plasma membrane G protein-coupled receptors (GPCRs). Early studies identified an essential role for the CaSR in systemic calcium homeostasis through its ability to ...
Benoit, Yves +3 more
core +1 more source
Primary hyperparathyroidism [PDF]
Nature Reviews Disease Primers, 2016 Primary hyperparathyroidism (PHPT) is a common disorder in which parathyroid hormone (PTH) is excessively secreted from one or more of the four parathyroid glands. A single benign parathyroid adenoma is the cause in most people. However, multiglandular disease is not rare and is typically seen in familial PHPT syndromes. The genetics of PHPT is usually
Bilezikian, John P +5 more
+11 more sources
Mineral and bone disorders in peritoneal dialysis
Bulletin de la Dialyse à Domicile, 2022 Introduction Disorders of mineral and bone metabolism are common in dialysis patients and are responsible for an increased risk of fracture, cardiovascular risk and mortality. The mineral and bone disorder most frequently found in peritoneal dialysis
imane Houem +5 more
doaj +1 more source
Stability of extemporaneously prepared cinacalcet oral suspensions [PDF]
, 2018 Purpose The stability of extemporaneously prepared cinacalcet suspensions over 90 days was evaluated. Methods Cinacalcet 5-mg/mL suspension was prepared by triturating 30-mg cinacalcet tablets.
Chablani, Lipika +2 more
core +2 more sources
Case Reports in Endocrinology, 2021 Hypercalcaemia and its systemic sequelae are a relatively common finding amongst patients in the field of endocrinology. Primary hyperparathyroidism, a frequent cause of hypercalcaemia, is often seen among middle-aged female patients, typically resulting
Maxim Barnett +4 more
doaj +1 more source
Primary hyperparathyroidism: diagnostics and surgical management
MGM Journal of Medical Sciences, 2020 Primary hyperparathyroidism is an endocrinological pathology of parathyroid glands. Its predominant form is a single parathyroid gland adenoma. We present a case of a 53-year-old patient, who was referred with primary hyperparathyroidism.
Leszek Sulkowski, Maciej Matyja
doaj +1 more source
Secondary and tertiary hyperparathyroidism in chronic kidney disease
Остеопороз и остеопатии, 2017 In the treatment of secondary hyperparathyroidism of end-stage chronic kidney disease, vitamin D receptor activation and allosteric modulators of the calcium-sensing receptor inhibit glandular hyperplasia, reduce parathyroid hormone levels, impact on ...
Lilit V. Egshatyan +2 more
doaj +1 more source
Frontiers in Endocrinology, 2023 BackgroundThe existing literature on the relationship of hyperparathyroidism with both blood counts and biochemical indicators primarily comprises observational studies, which have produced inconsistent findings.
Yan Jiang +10 more
doaj +1 more source
Pediatric thyroid disease: when is surgery necessary, and who should be operating on our children? [PDF]
, 2013 Surgical diseases of the thyroid in the pediatric population represent a diverse set of both benign and malignant conditions. Overall, incidence is rare.
Breuer, Christopher +3 more
core +1 more source
Kidney Research and Clinical Practice, 2012 Persistent hyperparathyroidism affects renal outcomes and mortality. After kidney transplantation, cinacalcet is not approved as treatment for hyperparathyroidism. Parathyroidectomy, on the other hand, reverses electrolytes and mineral bone metabolism in
Ekamol Tantisattamo, David D. Ono
doaj +1 more source