Results 91 to 100 of about 20,336 (222)

The DYRK Family: A Key Regulator of Metabolic Homeostasis and Its Therapeutic Potential in Kidney Diseases

MedComm – Future Medicine, Volume 5, Issue 1, March 2026.
The DYRK family, a pivotal metabolic homeostasis regulator, mediates crosstalk between metabolic disorders and CKD via subtype‐specific mechanisms: DYRK1A drives diabetic (CKD risk), DYRK1B exacerbates metabolic renal injury, DYRK2 contributes to renal osteodystrophy, while DYRK3/4 remain unelucidated.
Yixuan Zhu, Pengfei Qiao, Yukun Gan, Xiushuo Fu, Xiayue Huang, Sirui Sun, Yafei Gou, Wenjie Xia, Feng Ma, Limin Liu   +9 more
wiley   +1 more source

RNA‐Binding Proteins and Ferroptosis in Cancer: Mechanism and Therapeutic Implications

MedComm – Oncology, Volume 5, Issue 1, March 2026.
Ferroptosis critically influences cancer cell fate and represents a promising therapeutic strategy. Emerging evidence identifies RNA‐binding proteins (RBPs) as key post‐transcriptional regulators of ferroptosis. The figure summarizes ferroptosis‐related RBPs across cancers: blue RBPs act as tumor suppressors by promoting ferroptosis, whereas red RBPs ...
Linlin Chang, Bin Lu, Haotian Shang, Wanjing Ding, Chunhua Wei, Xiaotian Qi, Pengxing He   +6 more
wiley   +1 more source

A Case of Intestinal Granular Calcifications Associated With Phosphate Binder Use in a Patient on Hemodialysis

Clinical Case Reports
An experienced physician correctly identified a high‐intensity intestinal X‐ray from Lanthanum Carbonate, preventing unnecessary tests and enabling proper treatment. Awareness of this is vital in managing renal failure patients.
Takaaki Nagao, Yosuke Azuma, Ryo Ichibayashi   +2 more
doaj   +1 more source

Guidelines for writing definitions in ontologies [PDF]

, 2017
Ontologies are being used increasingly to promote the reusability of scientific information by allowing heterogeneous data to be integrated under a common, normalized representation. Definitions play a central role in the use of ontologies both by humans
Ruttenberg, Alan, Seppälä, Selja, Smith, Barry   +2 more
core   +1 more source

Alkaline phosphatases in the complex chronic kidney disease-mineral and bone disorders [PDF]

, 2018
Alkaline phosphatases (APs) remove the phosphate (dephosphorylation) needed in multiple metabolic processes (from many molecules such as proteins, nucleotides, or pyrophosphate). Therefore, APs are important for bone mineralization but paradoxically they
Aguilar, Armando, Benito, Silvia, Bover, Jordi, Cozzolino, Mario, Dasilva, Iara, López-Báez, Víctor, Mazzaferro, Sandro, Ramos, Alejandra, Ureña, Pablo   +8 more
core   +1 more source

A Risk Developing Prominent Hyperphosphatemia Leading to Renal Failure in Cup‐Like Leukemia

eJHaem, Volume 7, Issue 2, April 2026.
Osamu Imataki, Makiko Uemura, Shumpei Uchida, Akihiro Takeuchi   +3 more
wiley   +1 more source

Recessive mutation in GALNT3 causes hyperphosphatemic familial tumoral calcinosis associated with chronic recurrent multifocal osteomyelitis

The Turkish Journal of Pediatrics, 2019
Hyperphosphatemic familial tumoral calcinosis is a rare autosomal recessive disorder that is characterized by persistent hyperphosphatemia and extra-articular calcifications.
Jumana Albaramki, Haitham Dmour, Mohammad Shboul, Carine Bonnard, Byrappa Venkatesh, Rasha Odeh   +5 more
doaj   +1 more source

Systemic Control of Bone Homeostasis by FGF23 Signaling [PDF]

, 2016
The regulation of phosphate metabolism as an influence on bone homeostasis is profound. Recent advances in understanding the systemic control of Fibroblast growth factor-23 (FGF23) has uncovered novel effectors of endocrine feedback loops for calcium ...
Clinkenbeard, Erica L., White, Kenneth E.   +1 more
core   +1 more source

Mycobacterial panniculitis caused by Mycobacterium thermoresistibile in a cat. [PDF]

, 2016
Case summaryA domestic shorthair cat was evaluated for chronic, bilateral, ulcerative dermatitis affecting the inguinal region and lateral aspects of both pelvic limbs.
Keel, M Kevin, Reagan, Krystle L, Sykes, Jane E, Vishkautsan, Polina   +3 more
core   +2 more sources

Benefits of Sevelamer on Markers of Bone Turnover in Taiwanese Hemodialysis Patients

Journal of the Formosan Medical Association, 2010
Sevelamer hydrochloride is a recently developed phosphate binder, which is a quaternary amine anion exchanger without calcium or aluminum. Sevelamer is effective in controlling hyperphosphatemia without increasing the calcium load in chronic hemodialysis
Yu-Feng Lin, Yung-Ming Chen, Kuan-Yu Hung, Tzong-Shinn Chu, Wei-Chih Kan, Chih-Yuan Huang, Shuei-Liong Lin, Tze-Wah Kao, Jenq-Wen Huang, Wen-Chih Chiang, Chung-Jen Yen, Tun-Jun Tsai, Kwan-Dun Wu, Ming-Shiou Wu   +13 more
doaj   +1 more source