Results 71 to 80 of about 16,718 (212)

Hyperphosphatemia-related biochemical profiles and clinical correlates in patients receiving maintenance hemodialysis: a single-center retrospective cross-sectional study

Frontiers in Medicine
BackgroundHyperphosphatemia is common in maintenance hemodialysis (MHD) and often coexists with other abnormalities of chronic kidney disease–mineral and bone disorder (CKD-MBD).
Lei Zhang, Licun Zhang
doaj   +1 more source

Advances in FGF/FGFR Signaling: Implications for Disease and Therapy

MedComm, Volume 7, Issue 9, September 2026.
The FGF/FGFR signaling is indispensable for the maintenance of physiological homeostasis and governs multiple biological processes, including embryonic development, bone metabolism, angiogenesis, and neurogenesis, whereas aberrant hyperactivation of this pathway drives the progression of malignancies and autoimmune disorders, including inflammatory ...
Miaoyu Song, Xi Liu, Yang Xiao, Yongsheng Li, Huakan Zhao   +4 more
wiley   +1 more source

The management of hyperphosphatemia by lanthanum carbonate in chronic kidney disease patients

, 2012
Takashi Shigematsu, Yuri Nakashima, Masaki Ohya, Koichi Tatsuta, Daisuke Koreeda, Wataru Yoshimoto, Shintaro Yamanaka, Toshifumi Sakaguchi, Yoshiyuki Hanba, Toru Mima, Shigeo NegiDivision of Nephrology, Department of Internal Medicine, Wakayama Medical ...
Shigematsu T, Yoshimoto W, Koreeda D, Sakaguchi T, Nakashima Y, Negi S, Yamanaka S, Mima T, Tatsuta K, Ohya M, Hanba Y   +10 more
core  

Phenotypic and Genotypic Landscape of Sitosterolemia in China: Including a Rare Case With Nephronophthisis

Molecular Genetics &Genomic Medicine, Volume 14, Issue 9, September 2026.
This study describes the first reported case of concurrent sitosterolemia (STSL) and nephronophthisis (NPHP). Additionally, we provide a systematic review of the clinical and genetic characteristics of Chinese STSL patients, representing the largest comprehensive cohort in China to date.
Dan Ding, Hongmei Wu, Fei Zhao, Bixia Zheng, Qiuxia Chen   +4 more
wiley   +1 more source

Sevelamer carbonate in the treatment of hyperphosphatemia in patients with chronic kidney disease on hemodialysis

, 2008
Vincenzo Savica1,2, Domenico Santoro1, Paolo Monardo2, Agostino Mallamace1, Guido Bellinghieri11Experimental and Clinic Department of Internal Medicine and Pharmacology, University of Messina, Italy; 2Nephrology and Dialysis Unit, Papardo Hospital ...
Guido Bellinghieri, Vincenzo Savica, Paolo Monardo, Agostino Mallamace, Domenico Santoro   +4 more
core  

Is there any link between Hyperphosphatemia, Hypoalbuminemia, and Hypocalcemia with Hospital Outcomes in COVID-19 Patients?

, 2023
Background: Disturbed biochemical factors have been observed in viral infections including SARS, Ebola virus, and now COVID-19. This study aimed to evaluate the association between Calcium axis' derangements and hospital duration, ICU admission ...
Akbari, M., Siavash, M., Rezaeifar, A., Tabatabaee, A.   +3 more
core   +1 more source

Leveraging Healthy Volunteers for Anticancer Drug Clinical Pharmacology Studies: A Review Article Featuring Futibatinib as an Example

Clinical and Translational Science, Volume 19, Issue 9, September 2026.
ABSTRACT Early clinical development of anticancer drugs traditionally focused on exploring candidate treatments in patients. For instance, due to their cytotoxic action, administration of chemotherapies to healthy volunteers (HVs) for evaluation of their pharmacokinetic profiles was not considered feasible nor ethical from a safety and tolerability ...
Aernout D. van Haarst, Sabina Paglialunga, Ziv Machnes, Ikuo Yamamiya, Nanae Hangai, Aram Oganesian   +5 more
wiley   +1 more source

Management of hyperphosphatemia in patients with end-stage renal disease: focus on lanthanum carbonate

, 2009
Veerle P Persy, Geert J Behets, Marc E De Broe, Patrick C D’HaeseLaboratory of Pathophysiology, University of Antwerp, BelgiumAbstract: Elevated serum phosphate levels as a consequence of chronic kidney disease (CKD) contribute to the increased
de Broe, Marc E., d' Haese, Patrick C., Behets, Geert, Geert J Behets, Persy, Veerle, Patrick C D’Haese, Veerle P Persy, Marc E De Broe   +7 more
core  

Hyperphosphatemia Is an Independent Risk Factor for Mortality in Critically Ill Patients: Results from a Cross-Sectional Study. [PDF]

, 2015
BACKGROUND Phosphate imbalances or disorders have a high risk of morbidity and mortality in patients with chronic kidney disease. It is unknown if this finding extends to mortality in patients presenting at an emergency room with or without normal ...
Sauter, Thomas, Dominik G Haider, Ahmad, Sufian S., Haider, Dominik G., Valentin Fuhrmann, Haider, Dominik, Ahmad, Sufian S, Gregor Lindner, Fiedler, Georg-Martin, Aristomenis K Exadaktylos, Sufian S Ahmad, Alexander Benedikt Leichtle, Lindner, Gregor, Leichtle, Alexander Benedikt, Thomas Sauter, Exadaktylos, Aristomenis K., Fuhrmann, Valentin, Wolzt, Michael, Exadaktylos, Aristomenis, Michael Wolzt, Georg-Martin Fiedler, Haider DG, Haider Dominik G., Leichtle Alexander Benedikt, Wolzt M, Ahmad Sufian S., Fuhrmann Valentin, Ahmad SS, Wolzt Michael, Fiedler Georg-Martin, Leichtle AB, Sauter T, Sauter Thomas, Exadaktylos AK, Fuhrmann V, Exadaktylos Aristomenis K., Lindner Gregor, Lindner G, Fiedler GM   +38 more
core   +3 more sources

Use of Intralipid Therapy and Therapeutic Plasma Exchange in the Management of Cholecalciferol Rodenticide Exposure in a Dog: A Case Report

Journal of Veterinary Emergency and Critical Care, Volume 36, Issue 5, Page 696-702, September/October 2026.
ABSTRACT Objective To describe the presentation and outcome of a case of suspected cholecalciferol rodenticide intoxication managed with both intralipid emulsion (ILE) and therapeutic plasma exchange (TPE). Case Summary A 3‐year‐old, neutered female, crossbreed dog presented for acute‐onset vomiting and lethargy after suspected exposure to ...
Tanvi A. Kamat, Kara D. Altman, Emma Donnelly, Neus Elias Santo‐Domingo   +3 more
wiley   +1 more source