Effects of iron-based phosphate binders on mortality and cardiovascular events in patients receiving maintenance dialysis [PDF]
Scientific Reports, 2023 Phosphate binders are the main treatment for hyperphosphatemia in patients with chronic kidney disease, and iron-based phosphate binders have been used with increasing frequency in recent years.
Akihito Tanaka +5 more
doaj +2 more sources
Phosphate binders affect vitamin K concentration by undesired binding, an in vitro study [PDF]
BMC Nephrology, 2017 Background Vascular calcification is a major contributing factor to mortality in end stage renal disease (ESRD). Despite the efficacy of phosphate binders to improve hyperphosphatemia, data on vascular calcification are less clear.
A. Neradova +5 more
doaj +2 more sources
A comparison between the combined effect of calcium carbonate with sucroferric oxyhydroxide and other phosphate binders: an in vitro and in vivo experimental study [PDF]
BMC Nephrology, 2019 Background Approximately 30% of patients on dialysis received combination therapy for their phosphate binder prescription; however, few studies for combined effects of phosphate binders are reported.
Atsushi Yaguchi +7 more
doaj +2 more sources
How to assess the efficacy of phosphate binders
Nefrologia, 2017 Background and aims: The efficacy of phosphate binders is difficult to be estimated clinically. This study analyzes the changes in serum phosphate and urinary phosphate excretion after the prescription of phosphate binders (PB) in patients with chronic ...
FRANCISCO Caravaca +2 more
exaly +3 more sources
Journal of Pharmacy and Bioallied Sciences, 2019 Objective: Hyperphosphatemia in end-stage renal disease (ESRD) is associated with many serious patient-level consequences including cardiovascular events and mortality.
Syed Arman Rabbani +4 more
doaj +2 more sources
Differential effects of phosphate binders on vitamin D metabolism in chronic kidney disease [PDF]
Nephrology Dialysis Transplantation, 2020 Charles Ginsberg +2 more
exaly +2 more sources
Quantifying the Contribution of Nondialytic Factors Affecting Predialysis Serum Phosphate Level When Comparing Hemodiafiltration with Hemodialysis [PDF]
ToxinsHyperphosphatemia is a major complication in patients with kidney failure undergoing dialysis and is strongly associated with cardiovascular disease, vascular calcification, and increased mortality.
John T. Daugirdas
doaj +2 more sources
Iron-based phosphate binders: do they offer advantages over currently available phosphate binders? [PDF]
CKJ: Clinical Kidney Journal, 2015 Armando Luis Negri, Pablo Urena-Torres
exaly +2 more sources
Phosphate Absorption and Hyperphosphatemia Management in Kidney Disease: A Physiology-Based Review
Kidney Medicine, 2021 Phosphate absorption occurs in the gastrointestinal tract through paracellular absorption and transcellular transport. The paracellular pathway does not saturate and has a significantly higher absorption capacity than does the transcellular pathway ...
Steven N. Fishbane, Sagar Nigwekar
doaj +1 more source
The Impact of Phosphorus Management Today on Quality of Life: Patient Perspectives
Kidney Medicine, 2022 Patients with kidney failure and early stages of chronic kidney disease often develop hyperphosphatemia, which is associated with negative outcomes. The reduction of phosphate levels is the established clinical practice.
Derek Forfang +2 more
doaj +1 more source