Results 1 to 10 of about 16,718 (212)

Understudied Hyperphosphatemia (Chronic Kidney Disease) Treatment Targets and New Biological Approaches

Medicina, 2023
Hyperphosphatemia is a secondary disorder of chronic kidney disease that causes vascular calcifications and bone-mineral disorders. As per the US Centers for Disease Control and Prevention, renal damage requires first-priority medical attention for ...
Ajeeta Anand, Hideki Aoyagi
doaj   +2 more sources

Hyperphosphatemia and Outcomes in Critically Ill Patients: A Systematic Review and Meta-Analysis

Frontiers in Medicine, 2022
IntroductionSerum phosphate level is often deranged during critical illness. Hyperphosphatemia, as a marker of disease severity, attracts more and more attention.
Hui-Bin Huang, Wen-He Zheng
exaly   +3 more sources

Protein and Phosphate Intakes are Associated with Hyperphosphatemia in Hemodialysis Patients at Sanglah Hospital, Bali, Indonesia [PDF]

Majalah Kedokteran Bandung, 2022
Increased chronic kidney disease (CKD) mortality rate is significantly associated with increased blood phosphate levels. Hyperphosphatemia control is one of the main focuses in the management of hemodialysis (HD) patients.
Made Dyah Vismita Indramila Duarsa, Yenny Kandarini, Gede Wira Mahadita, Ni Nyoman Shinta Prasista Sari   +3 more
doaj   +5 more sources

An explainable machine learning model for predicting high phosphorus risk in patients on maintenance hemodialysis: a multicenter retrospective study [PDF]

BMC Medical Informatics and Decision Making
Background Hyperphosphatemia is a common complication in hemodialysis and serves as a key marker for evaluating dialysis adequacy. This study aimed to develop an interpretable machine learning (ML) model to predict the risk of hyperphosphatemia in ...
Jiaoyan Chen, Jurong Yang, Mingyue Hou, Jingrong Peng, Yunyan Wang, Kui Xiang   +5 more
doaj   +2 more sources

Efficacy and safety of ferric citrate tablets in Chinese patients with hyperphosphatemia undergoing maintenance hemodialysis: a multicenter, randomized, open-label, active-controlled, phase III trial [PDF]

Renal Failure
Background This study aimed to evaluate the efficacy and safety of ferric citrate tablets in Chinese patients with hyperphosphatemia undergoing maintenance hemodialysis (MHD).Methods In this phase III, multicenter, randomized, open-label, non-inferiority
Jie Ma, Bicheng Liu, Jialiang Pang, Pei Wang, Ying Li, Caili Wang, Donghui Zheng, Xiaoping Wang, Xiumei Hu, Jianrong Zhao, Xinzhou Zhang, Changchun Cao, Zunsong Wang, Li Xing, Suhua Li, Hong Cheng, Jian Huang, Yi Yang, Xiaolan Chen, Kun Ye, Tiekun Yan, Lianhua Chen, Guojuan Zhang, Feng Zheng, Siyuan Teng, Qing Zhu, Hong Liu, Xuemei Li   +27 more
doaj   +2 more sources

Association between serum phosphate levels and outcome among critically ill newborns: a retrospective cohort study [PDF]

Frontiers in Pediatrics
BackgroundThis study aimed to explore the relationship between serum phosphate levels and clinical outcomes in critically ill neonates.MethodsA retrospective cohort study was conducted using the Pediatric Intensive Care (PIC) database from (2010- 2018 ...
Lisha Bao, Xiaohui Liu, Caixia Zhao, Jing Li, Dan Li, Zhifang Du   +5 more
doaj   +2 more sources

Estrogen inhibits renal Na-Pi Co-transporters and improves klotho deficiency-induced acute heart failure

Redox Biology, 2021
Objective and hypothesis: Klotho is an aging-suppressor gene. Mutation of Klotho gene causes hyperphosphatemia and acute heart failure. However, the relationship of hyperphosphatemia and acute heart failure is unclear.
Kai Chen, Zhongjie Sun
doaj   +1 more source

Association between phosphate disturbances and mortality among critically ill patients with sepsis or septic shock

BMC Pharmacology and Toxicology, 2021
Objective The aim of this study is to examine the association of hypophosphatemia and hyperphosphatemia on the first day of ICU admission with mortality in septic critically ill patients. Methods In this retrospective cohort study, all adult patients who
Shmeylan A. Al Harbi, Hasan M. Al-Dorzi, Albatool M. Al Meshari, Hani Tamim, Sheryl Ann I. Abdukahil, Musharaf Sadat, Yaseen Arabi   +6 more
doaj   +1 more source

Association of Serum Phosphate Derangement With Mortality in Patients on Continuous Renal Replacement Therapy

Canadian Journal of Kidney Health and Disease, 2022
Background: There is limited evidence on the association of serum phosphate with mortality in patients receiving continuous renal replacement therapy (CRRT).
Charat Thongprayoon, Yeshwanter Radhakrishnan, Wisit Cheungpasitporn, Tananchai Petnak, Fawad Qureshi, Michael A. Mao, Kianoush B. Kashani   +6 more
doaj   +1 more source

Association between serum fibroblast growth factor‐23 concentration and development of hyperphosphatemia in normophosphatemic dogs with chronic kidney disease

Journal of Veterinary Internal Medicine, 2021
Background Fibroblast growth factor (FGF)‐23 is increased first in the sequence of changes associated with chronic kidney disease (CKD)‐mineral and bone disorder.
Hirosumi Miyakawa, Huai‐Hsun Hsu, Mizuki Ogawa, Ryota Akabane, Yuichi Miyagawa, Naoyuki Takemura   +5 more
doaj   +1 more source