Results 31 to 40 of about 20,554 (221)

Chronic Hyperphosphatemia and Vascular Calcification Are Reduced by Stable Delivery of Soluble Klotho [PDF]

, 2016
αKlotho (αKL) regulates mineral metabolism, and diseases associated with αKL deficiency are characterized by hyperphosphatemia and vascular calcification (VC).
Bhaskaran, Manoj, Cass, Taryn A., Clinkenbeard, Erica L., Cramer, Martin S., Hum, Julia M., Johnson, Robert L., O’Bryan, Linda M., Smith, Rosamund C., Tatiparthi, Arun K., White, Kenneth E., Wilson, Jonathan M.   +10 more
core   +1 more source

The calcilytic agent NPS 2143 rectifies hypocalcemia in a mouse model with an activating calcium-sensing-receptor (CaSR) mutation:relevance to autosomal dominant hypocalcemia type 1 (ADH1) [PDF]

, 2015
Autosomal dominant hypocalcemia type 1 (ADH1) is caused by germline gain-of-function mutations of the calcium-sensing receptor (CaSR) and may lead to symptomatic hypocalcemia, inappropriately low serum parathyroid hormone (PTH) concentrations and ...
Allen M. Spiegel, Breitwieser, Dong, Drude, Enikö Kallay, Fadil M. Hannan, Gerard V. Walls, Gowen, Hannan, Hannan, Harding, Hofer, Hough, Hu, Hu, Huang, Jianxin Hu, John, Kinoshita, Kumar, Leach, Leach, Letz, Letz, Lia-Baldini, Loupy, M. Andrew Nesbit, Miedlich, Nemeth, Nemeth, Nesbit, Pearce, Pearce, Petrel, Rajesh V. Thakker, Raue, Roger D. Cox, Stechman, Tertius A. Hough, Thim, Valerie N. Babinsky, Vargas-Poussou, Watanabe, William D. Fraser, Yamamoto   +44 more
core   +1 more source

Association between pruritus and serum concentrations of parathormone, calcium and phosphorus in hemodialysis patients. [PDF]

, 2013
Chronic renal disorders have a progressive course in most cases, and finally result in end-stage renal disease (ESRD). Hemodialysis (HD) is one of the mainstays in the treatment of these patients. Disturbance in calcium (Ca) and phosphorus (P) metabolism
Bayzayi, F., Haddad, M., Joshaghani, H.R., Qorbani, M., Tajbakhsh, R.   +4 more
core   +2 more sources

Dietary Therapy for Managing Hyperphosphatemia [PDF]

Clinical Journal of the American Society of Nephrology, 2020
Hyperphosphatemia is a prevalent complication in patients with advanced CKD, affecting approximately 50% of those treated with maintenance hemodialysis ([1][1],[2][2]). In the normal state, phosphate homeostasis is maintained through the interplay between intestinal absorption, bone deposition ...
Yoko Narasaki, Connie M. Rhee
openaire   +2 more sources

Clinical Characteristics and Outcomes of Hyperphosphatemia in Patients with Chronic Kidney Disease Stages 1–2

Kidney & Blood Pressure Research
Introduction: There was limited research on the epidemiology of hyperphosphatemia in early-stage chronic kidney disease (CKD) patients. We aimed to explore the clinical characteristics and prognostic value of hyperphosphatemia in patients with CKD stages
Chao Xie, Qi Gao, Jiao Liu, Licong Su, Mingzhen Pang, Shiyu Zhou, Yaozhong Kong, Sheng Nie, Min Liang   +8 more
doaj   +1 more source

The role of the gastrointestinal tract in phosphate homeostasis in health and chronic kidney disease. [PDF]

, 2013
For a number of years, there has been increasing interest in the concept of directly targeting intestinal phosphate transport to control hyperphosphatemia in chronic kidney disease. However, progress has been slow due to the paucity of information on the
Debnam, ES, Marks, J, Unwin, RJ
core   +1 more source

Hyperphosphatemia-Induced Oxidant/Antioxidant Imbalance Impairs Vascular Relaxation and Induces Inflammation and Fibrosis in Old Mice

Antioxidants, 2021
Aging impairs vascular function, but the mechanisms involved are unknown. The aim of this study was to analyze whether aging-related hyperphosphatemia is implied in this effect by elucidating the role of oxidative stress.
Ana Asenjo-Bueno, Elena Alcalde-Estévez, Mariam El Assar, Gemma Olmos, Patricia Plaza, Patricia Sosa, Patricia Martínez-Miguel, María Piedad Ruiz-Torres, Susana López-Ongil   +8 more
doaj   +1 more source

The Effects of a Serious Game on Knowledge of CKD, Hyperphosphatemia, and Phosphate Binders in CKD Patients Stage 4/5: A Prospective Multinational Study [conference abstract] [PDF]

, 2015
This is an abstract from a poster presented at the 52nd ERA-EDTA Congress, May 28th-31st, 2015, London, United ...
Hill, P., Kato, Pam
core   +1 more source

Recombinant human parathyroid hormone in the therapy of hypoparathyroidism [PDF]

Терапевтический архив, 2017
Hypoparathyroidism is an endocrine disease that results from deficiency or complete absence of parathyroid hormone (PTH), a biologically active 84-amino acid polypeptide.
A K Eremkina, N G Mokrysheva, E V Kovaleva, Yu A Krupinova   +3 more
doaj   +1 more source

ICU-Admission Hyperphosphataemia Is Related to Shock and Tissue Damage, Indicating Injury Severity and Mortality in Polytrauma Patients

Diagnostics, 2021
Hyperphosphataemia can originate from tissue ischaemia and damage and may be associated with injury severity in polytrauma patients. In this retrospective, single-centre study, 166 polytrauma patients (injury severity score (ISS) ≥ 16) primarily ...
Christopher Rugg, Mirjam Bachler, Robert Kammerlander, Daniel Niederbrunner, Johannes Bösch, Stefan Schmid, Janett Kreutziger, Mathias Ströhle   +7 more
doaj   +1 more source