Results 31 to 40 of about 16,718 (212)

Research advances on the pathogenesis of vascular calcification caused by hyperphosphatemia associated with chronic kidney disease

Linchuang shenzangbing zazhi
Phosphorus is one of essential nutrients for the human body that plays an indispensable role in various physiological processes. The balance of blood phosphorus is crucial in all living organisms.
Wang Yu-han, Su Ji-li, Zhou Xiao-shuang
doaj   +3 more sources

The Relationship between Knowledge about Phosphorus, Dietary Phosphorus Intake and Serum Phosphorus Level in Maintenance Hemodialysis Patients

Journal of High Institute of Public Health, 2022
Background: Renal diet knowledge -especially phosphorus knowledge- is generally poor in Maintenance Hemodialysis (MHD) patients due to the complexity of information about dietary phosphorus thus causing poor compliance to dietary phosphorus guidelines ...
Rana H. Emara, Doha M. Abo Zahra
doaj   +1 more source

Hyperphosphatemia Management in Patients with Chronic Kidney Disease

Saudi Pharmaceutical Journal, 2015
Hyperphosphatemia in chronic kidney disease (CKD) patients is a potentially life altering condition that can lead to cardiovascular calcification, metabolic bone disease (renal osteodystrophy) and the development of secondary hyperparathyroidism (SHPT ...
Ahmed M. Shaman, Stefan R. Kowalski
doaj   +1 more source

Dose-Response of Tenapanor in Patients With Hyperphosphatemia Undergoing Hemodialysis in Japan—A Phase 2 Randomized Trial

Kidney International Reports, 2022
Introduction: Simplified, but effective, hyperphosphatemia treatments with novel mechanisms of action, tolerable safety profiles, and low pill burden are needed for patients undergoing hemodialysis.
Masaaki Inaba, Yotaro Une, Kazuaki Ikejiri, Hironori Kanda, Masafumi Fukagawa, Tadao Akizawa   +5 more
doaj   +1 more source

Clinical Characteristics and Outcomes of Hyperphosphatemia in Patients with Chronic Kidney Disease Stages 1–2

Kidney & Blood Pressure Research
Introduction: There was limited research on the epidemiology of hyperphosphatemia in early-stage chronic kidney disease (CKD) patients. We aimed to explore the clinical characteristics and prognostic value of hyperphosphatemia in patients with CKD stages
Chao Xie, Qi Gao, Jiao Liu, Licong Su, Mingzhen Pang, Shiyu Zhou, Yaozhong Kong, Sheng Nie, Min Liang   +8 more
doaj   +1 more source

Hyperphosphatemia-Induced Oxidant/Antioxidant Imbalance Impairs Vascular Relaxation and Induces Inflammation and Fibrosis in Old Mice

Antioxidants, 2021
Aging impairs vascular function, but the mechanisms involved are unknown. The aim of this study was to analyze whether aging-related hyperphosphatemia is implied in this effect by elucidating the role of oxidative stress.
Ana Asenjo-Bueno, Elena Alcalde-Estévez, Mariam El Assar, Gemma Olmos, Patricia Plaza, Patricia Sosa, Patricia Martínez-Miguel, María Piedad Ruiz-Torres, Susana López-Ongil   +8 more
doaj   +1 more source

Hyperphosphatemia, Phosphoprotein Phosphatases, and Microparticle Release in Vascular Endothelial Cells.

, 2015
Hyperphosphatemia in patients with advanced CKD is thought to be an important contributor to cardiovascular risk, in part because of endothelial cell (EC) dysfunction induced by inorganic phosphate (Pi).
Jeremy R. Brown (5405240), Maryam Ghaderi-Najafabadi (7669784), Karl E. Herbert (7643471), Barbara-Emily Tregunna (7669781), Nigel J. Brunskill (7418450), Nima Abbasian (441062), Alison H. Goodall (7579298), Alan Bevington (7240580), James O. Burton (7199093)   +8 more
core   +4 more sources

Recombinant human parathyroid hormone in the therapy of hypoparathyroidism [PDF]

Терапевтический архив, 2017
Hypoparathyroidism is an endocrine disease that results from deficiency or complete absence of parathyroid hormone (PTH), a biologically active 84-amino acid polypeptide.
A K Eremkina, N G Mokrysheva, E V Kovaleva, Yu A Krupinova   +3 more
doaj   +1 more source

ICU-Admission Hyperphosphataemia Is Related to Shock and Tissue Damage, Indicating Injury Severity and Mortality in Polytrauma Patients

Diagnostics, 2021
Hyperphosphataemia can originate from tissue ischaemia and damage and may be associated with injury severity in polytrauma patients. In this retrospective, single-centre study, 166 polytrauma patients (injury severity score (ISS) ≥ 16) primarily ...
Christopher Rugg, Mirjam Bachler, Robert Kammerlander, Daniel Niederbrunner, Johannes Bösch, Stefan Schmid, Janett Kreutziger, Mathias Ströhle   +7 more
doaj   +1 more source

Efficacy of DZ1462, a Novel Sodium-phosphate Transporter Inhibitor, on 5/6 Nephrectomy-induced Hyperphosphatemia Model Rats

Shiyan dongwu yu bijiao yixue, 2022
Objective To study the efficacy of DZ1462, a novel sodium-phosphate transporter inhibitor, on rat hyperphosphatemia models established by 5/6 nephrectomy.Methods Totally 156 rats were randomly selected into four groups.
LU Xiao, ZHANG Lin, JI Hui, JIANG Shanxiang   +3 more
doaj   +1 more source