Results 51 to 60 of about 12,753 (177)
Novel Treatments from Inhibition of the Intestinal Sodium–Hydrogen Exchanger 3
Csaba P Kovesdy,1 Adebowale Adebiyi,2 David Rosenbaum,3 Jeffrey W Jacobs,3 L Darryl Quarles1 1Division of Nephrology, University of Tennessee Health Science Center, Memphis, TN, USA; 2Department of Physiology, University of Tennessee Health Science ...
Kovesdy CP +4 more
doaj
Vascular Calcification: Mechanisms, Models, and Therapies
ABSTRACT Vascular calcification represents an active multifactorial process that mirrors several key features of skeletal bone mineralization. Clinically, it is characterized by diminished arterial compliance and increased arterial wall stiffness, both of which serve as independent predictors of significant adverse cardiovascular events.
Wenya Zhu +5 more
wiley +1 more source
[Hypophosphatemia and hyperphosphatemia].
Pathophysiology, clinical sequelae, and treatment for hypophosphatemia and hyperphosphatemia are discussed. Hypophosphatemia results from a variety of conditions including malnutrition, carbohydrate refeeding, acid-base disorders, and hormonal and drug effects. Patients suffering from severe hypophosphatemia may present with a variety of syndromes that
Michael P. Peppers +2 more
openaire +3 more sources
Efficacy of a Once-Daily Supplement in Managing Canine Chronic Kidney Disease
Background: Chronic kidney disease (CKD) in companion animals leads to progressive renal deterioration and metabolic complications such as hyperphosphatemia and metabolic acidosis, particularly in advanced stages.
Francesca Perondi +5 more
doaj +1 more source
The serum level of the morphogenetic protein fibroblast growth factor 23 (FGF-23) as a marker for the efficiency of hyperphosphatemia therapy with phosphate-binding agents in chronic kidney disease [PDF]
Aim. To study whether the excessive production of serum fibroblast growth factor 23 (FGF-23) may be reduced with phosphate-binding agents to treat hyperphosphatemia in patients with Stage VD chronic kidney disease (CKD). Subjects and methods.
N A Mukhin +4 more
doaj
Machine learning‐based predictive models outperform traditional risk scores in hemodialysis patients with comorbid urolithiasis by capturing nonlinear, dialysis‐specific interactions. These approaches enable more accurate prediction of stone recurrence, sepsis, hospitalization, and mortality, supporting personalized risk stratification and precision ...
Dipal Chaulagain +4 more
wiley +1 more source
Lanthanum Chloride in Vascular Calcification: Effects on Nano‐Hydroxyapatite and PPARγ/Wnt/β‐Catenin
This study elucidates the anti‐calcification mechanism of lanthanum chloride (LaCl₃) in rats with chronic kidney disease (CKD) and human vascular smooth muscle cells (hVSMCs). Unlike traditional phosphate binders, trace amounts of LaCl₃ can inhibit vascular calcification without lowering serum phosphorus levels.
Ting Zhang +11 more
wiley +1 more source
This study from the THAI‐CKD registry evaluated regional and KDIGO‐based variations in chronic kidney disease (CKD) aetiologies and complications among 3371 adults with CKD G3‐G5 across six regions of Thailand. Diabetic nephropathy was the leading aetiology, followed by hypertensive nephrosclerosis and CKD of unknown aetiology.
Kavita Jintanapramote +23 more
wiley +1 more source
Gigantic hip mass as the initial presentation of hyperphosphatemic familial tumoral calcinosis [PDF]
Introduction: Hyperphosphatemic familial tumoural calcinosis (HFTC) is a rare autosomal recessive disorder characterised by ectopic calcium phosphate deposition around the joints due to mutations affecting phosphate regulation.
Krishnan Surya +2 more
doaj +1 more source
An experienced physician correctly identified a high‐intensity intestinal X‐ray from Lanthanum Carbonate, preventing unnecessary tests and enabling proper treatment. Awareness of this is vital in managing renal failure patients.
Takaaki Nagao +2 more
doaj +1 more source

