Results 51 to 60 of about 20,554 (221)

Difficulties in correcting hyperphosphatemia in patients with chronic renal failure. A place of noncalcium-containing phosphate-binding drugs [PDF]

Терапевтический архив, 2016
The review considers the current views of the mechanisms of hyperphosphatemia in patients with chronic renal failure. It shows indications for the use of different classes of phosphate-binding drugs to correct hyperphosphatemia.
Yu S Milovanov, V V Fomin, L Yu Milovanova   +2 more
doaj  

Case Report: Efficacy of Reduced Doses of Asfotase Alfa Replacement Therapy in an Infant With Hypophosphatasia Who Lacked Severe Clinical Symptoms

Frontiers in Endocrinology, 2020
BackgroundHypophosphatasia is a rare bone disease characterized by impaired bone mineralization and low alkaline phosphatase activity. Here, we describe the course of bone-targeted enzyme replacement therapy with asfotase alpha for a female infant ...
Yasuko Fujisawa, Taichi Kitaoka, Hiroyuki Ono, Shinichi Nakashima, Keiichi Ozono, Tsutomu Ogata   +5 more
doaj   +1 more source

Hypovitaminosis D in acute inpatient cancer rehabilitation: Prevalence, predictors, and practical implications

PM&R, EarlyView.
Abstract Background Hypovitaminosis D is associated with adverse health outcomes, including increased mortality in patients with cancer. Although vitamin D insufficiency (23%–72%) and deficiency (20%–71%) are common among patients admitted to inpatient rehabilitation, their prevalence and predictors in cancer‐specific inpatient rehabilitation ...
Jegy M. Tennison, Minxing Chen, Areeba Hafeez, Ananya Krishnan, Sefia Khan, Rony Dev, Sonal Admane, Eduardo Bruera   +7 more
wiley   +1 more source

Transient Pseudohypoparathyroidism as a Cause of Late-onset Hypocalcemia in Neonates and Infants

Journal of the Formosan Medical Association, 2008
Transient pseudohypoparathyroidism is a rare cause of late-onset hypocalcemia in neonates and infants. The purpose of this study was to investigate the clinical presentation and natural course of transient pseudohypoparathyroidism in neonates and infants.
Cheng-Ting Lee, Wen-Yu Tsai, Yi-Ching Tung, Yong-Kwei Tsau   +3 more
doaj   +1 more source

Nicotinamide treatment in a murine model of familial tumoral calcinosis reduces serum Fgf23 and raises heart calcium [PDF]

, 2014
Mutations in the GALNT3 gene result in familial tumoral calcinosis, characterized by persistent hyperphosphatemia and ectopic calcific masses in soft tissues.
Gray, Amie K., Ichikawa, Shoji, Moe, Sharon M., Reilly, Austin M.   +3 more
core   +1 more source

Machine learning‐based predictive models versus traditional risk scores in hemodialysis patients with comorbid urolithiasis

Precision Medical Sciences, EarlyView.
Machine learning‐based predictive models outperform traditional risk scores in hemodialysis patients with comorbid urolithiasis by capturing nonlinear, dialysis‐specific interactions. These approaches enable more accurate prediction of stone recurrence, sepsis, hospitalization, and mortality, supporting personalized risk stratification and precision ...
Dipal Chaulagain, Muhammad Riaz, Mirza Muhammad Hadeed Khawar, Jawad Hameed, Malik Sohail Riaz   +4 more
wiley   +1 more source

Adverse effects of simulated hyper- and hypo-phosphatemia on endothelial cell function and viability. [PDF]

PLoS ONE, 2011
Dysregulation of phosphate homeostasis as occurs in chronic kidney disease is associated with cardiovascular complications. It has been suggested that both hyperphosphatemia and hypophosphatemia can cause cardiovascular disease.
Ai Peng, Tianfu Wu, Caihong Zeng, Dinesh Rakheja, Jiankun Zhu, Ting Ye, Jack Hutcheson, Nosratola D Vaziri, Zhihong Liu, Chandra Mohan, Xin J Zhou   +10 more
doaj   +1 more source

Determinants of Intradialytic Phosphate Removal in Hemodiafiltration From Real‐World Clinical Practice

Artificial Organs, EarlyView.
We show that convective therapy in the form of hemodiafiltration does not demonstrate a measurable effect on phosphate removal in a real‐world setting. On the other hand, session duration is the most important factor in determining phosphate removal in hemodialysis patients.
David A. Jaques, Roohi Chhabra, Haalah Shaaker, Priyanka Khatri, Andrew Davenport   +4 more
wiley   +1 more source

Conditional Deletion of Murine Fgf23: Interruption of the Normal Skeletal Responses to Phosphate Challenge and Rescue of Genetic Hypophosphatemia [PDF]

, 2016
The transgenic and knockout (KO) animals involving Fgf23 have been highly informative in defining novel aspects of mineral metabolism, but are limited by shortened lifespan, inability of spatial/temporal FGF23 control, and infertility of the global KO ...
Allen, Matthew R., Bellido, Teresita, Cass, Taryn A., Clinkenbeard, Erica L., Hum, Julia M., Ni, Pu, White, Kenneth E.   +6 more
core   +1 more source

Effect of Two Therapeutic Renal Diets on Hormonal and Regulatory Pathways Affecting Calcium Homeostasis in Cats With Early‐Stage Chronic Kidney Disease

Journal of Animal Physiology and Animal Nutrition, EarlyView.
ABSTRACT Chronic kidney disease (CKD) is a known risk factor for hypercalcemia in cats. Phosphate‐restricted diets have also been implicated in causing hypercalcemia, in part because phosphate restriction increases the Ca:P ratio. The primary objective of this study was to evaluate the impact of two different therapeutic renal foods on ionized (iCa ...
Jean A. Hall, Elizabeth M. Morris, Dale A. Fritsch, John J. Brejda, Kim M. Wilson   +4 more
wiley   +1 more source