Results 61 to 70 of about 16,718 (212)

Iron and Other Metal Ions in Human Health and Disease

MedComm, Volume 7, Issue 10, October 2026.
Iron, copper, zinc, and calcium orchestrate cellular function through distinct yet cooperative mechanisms: redox‐active iron and copper cycle between oxidation states to act as Fenton catalysts and electron carriers in oxidative phosphorylation (OXPHOS); redox‐inert zinc serves as a structural component of zinc‐finger proteins and a catalytic cofactor ...
Xiaofeng Dai, Jitian Li
wiley   +1 more source

Hyperphosphatemia Promotes Senescence of Myoblasts by Impairing Autophagy Through Ilk Overexpression, A Possible Mechanism Involved in Sarcopenia [PDF]

, 2018
In mammalians, advancing age is associated with sarcopenia, the progressive and involuntary loss of muscle mass and strength. Hyperphosphatemia is an aging-related condition involved in several pathologies.
López Ongil, Susana, De Melo Aroeira, Andresa, Sosa, Patricia, Rodríguez Puyol, Diego María, Rodriguez-Puyol, Diego, Plaza, Patricia, Martínez-Arias, Laura, Sosa Callejas, Patricia, Plaza Expósito, Patricia, Alcalde-Estevez, Elena, Alcalde Estévez, Elena, Olmos Centenera, Gemma, Olmos, Gemma, López-Ongil, Susana, Martínez Arias, Laura, Evelem de Melo Aroeira, Andresa, Alonso, Cristina, Ruíz-Torres, María P, Troyano Suárez, Nuria, Troyano, Nuria, Ruiz Torres, María Piedad   +20 more
core   +1 more source

DataSheet_1_Both hypophosphatemia and hyperphosphatemia are associated with increased mortality in septic patients.zip

, 2022
ObjectiveThis study was intended to explore the relationship between level of serum phosphate and prognosis in septic patients.MethodsData were obtained from the public database, which were divided into 2 subgroups according to whether they were ...
Zheng Liu (28397), Yihan Du (10973394), Teng Li (279243), Chenhu Li (13181241), Wei Chong (782416)   +4 more
core   +1 more source

Phosphate

Journal of Pediatric Critical Care, 2019
Phosphate plays an important role in cell structure and metabolism. Less than 1% of phosphate is in circulating serum and maintained within narrow range by hormones PTH, calcitonin, FGF23, vitamin D.
Kundan Mittal
doaj   +1 more source

Tenapanor Beyond Phosphate: Gut Sodium Transport, Stool Transit Time, and Volume Balance in Dialysis Patients

Hemodialysis International, Volume 30, Issue 4, Page 689-697, October 2026.
ABSTRACT Introduction Tenapanor, a minimally absorbed intestinal NHE3 inhibitor approved for hyperphosphatemia in dialysis, lowers phosphate and reduces intestinal sodium absorption. Its sodium–water signal may have implications beyond phosphate but remains poorly separated from diarrhea‐mediated losses and dialysis prescription artifacts. Methods This
Lucas Maciel de Almeida Corrêa, Luiggi Kevin Virgino Brandão, Clara Belo Gamon Santiago, Alexandre de Assis Barbosa, Gabriel Rian Mazur, Gabriel Costa de Santana, Yan Roberth Delmiro Silva, Letícia Esteves Dante, Ivan Felipe Dutra Júnior   +8 more
wiley   +1 more source

Implementation and effectiveness of an intensive education program on phosphate control among hemodialysis patients: a non-randomized, single-arm, single-center trial

BMC Nephrology, 2021
Background Hyperphosphatemia is a common complication in patients on maintenance hemodialysis. Patients’ adherence to phosphorus control can be improved by consistent education.
Jinmei Yin, Jun Yin, Rongli Lian, Peiqiu Li, Jing Zheng   +4 more
doaj   +1 more source

Hyperphosphatemia of chronic kidney disease [PDF]

Kidney International, 2008
Observational studies have determined hyperphosphatemia to be a cardiovascular risk factor in chronic kidney disease. Mechanistic studies have elucidated that hyperphosphatemia is a direct stimulus to vascular calcification, which is one cause of morbid cardiovascular events contributing to the excess mortality of chronic kidney disease.
Hruska, Keith A., Mathew, Suresh, Lund, Richard, Qiu, Ping, Pratt, Raymond   +4 more
openaire   +2 more sources

A Clinically Aligned Two‐Stage Machine Learning Framework for Predicting Hungry Bone Syndrome After Parathyroidectomy

Endocrinology, Diabetes &Metabolism, Volume 9, Issue 5, September 2026.
A clinically aligned two‐stage machine learning framework integrates preoperative and perioperative features to predict hungry bone syndrome after parathyroidectomy. Explainable risk stratification may support individualised calcium management and early intervention for high‐risk patients.
Shih‐Min Yin, Yu‐Chieh Lin, Tzu‐Hsun Hung, Shen‐En Chou, Shun‐Yu Chi, Fong‐Fu Chou, Yi‐Ju Wu, Si‐Yuan Wu, Jenn‐Jier James Lien, Po‐Chih Kuo, Yi‐Chia Chan   +10 more
wiley   +1 more source

Hypophosphatemia and Hyperphosphatemia

Critical Care Clinics, 1991
Pathophysiology, clinical sequelae, and treatment for hypophosphatemia and hyperphosphatemia are discussed. Hypophosphatemia results from a variety of conditions including malnutrition, carbohydrate refeeding, acid-base disorders, and hormonal and drug effects. Patients suffering from severe hypophosphatemia may present with a variety of syndromes that
Michael P. Peppers, Michael Geheb, Tusar Desai   +2 more
openaire   +3 more sources

MicroRNA‐Mediated Autophagy and Cardiovascular Diseases: Exploring the Crossroads of Atherosclerosis and Beyond

Journal of Clinical Laboratory Analysis, Volume 40, Issue 18, September 2026.
This graphical abstract illustrates the dynamic bidirectional crosstalk between microRNA biogenesis and autophagy, which serves as a critical regulatory axis in cardiovascular homeostasis. We highlight how specific miRNAs modulate autophagic flux to mitigate vascular inflammation and plaque instability, while concurrently, the autophagic machinery ...
Sepehr Ebrahimi‐Dehkordi, Amir Hossein Barjasteh, Aida Zarei, Sina Bazmi, Sarah Vaseghi, Sara Ashna, Amirreza Solati, Ali Yousefzadeh, Bita Safarzadeh Nasrabad, Zahra Mohammadi, Hamed Haddad Kashani, Mohammad Hossein Pourhanifeh   +11 more
wiley   +1 more source