Results 41 to 50 of about 16,312 (208)

Dose-Response of Tenapanor in Patients With Hyperphosphatemia Undergoing Hemodialysis in Japan—A Phase 2 Randomized Trial

Kidney International Reports, 2022
Introduction: Simplified, but effective, hyperphosphatemia treatments with novel mechanisms of action, tolerable safety profiles, and low pill burden are needed for patients undergoing hemodialysis.
Masaaki Inaba, Yotaro Une, Kazuaki Ikejiri, Hironori Kanda, Masafumi Fukagawa, Tadao Akizawa   +5 more
doaj   +1 more source

Control of hyperphosphatemia beyond phosphate [PDF]

, 2007
Hyperphosphatemia is a prevalent condition in the dialysis population and is associated with bad outcome. Block et al. present data from a post hoc analysis indicating that sevelamer, a noncalcium-containing phosphate binder, may confer a survival ...
Evenepoel, P.
core   +1 more source

Adenine-induced hyperphosphatemia in a murine model of renal insufficiency [PDF]

, 2017
Hyperphosphatemia in chronic kidney disease (CKD) patients is a risk factor for cardiovascular events, progressive kidney failure, and mortality. Improved therapeutic interventions to control hyperphosphatemia depend greatly on robust animal models that ...
Piccione, Michelle, Denise J Schwahn, Schwahn, Denise, Mark E Cook, Petkovich, Martin, Michelle L Piccione, Bishop, Jeff, Bobeck, Elizabeth, Fulmer, Tyler, Helvig, Christian, Tyler G Fulmer, Cook, Mark, Christian Helvig, Jeff W Bishop, Elizabeth A Bobeck, Martin Petkovich   +15 more
core   +1 more source

Clinical Characteristics and Outcomes of Hyperphosphatemia in Patients with Chronic Kidney Disease Stages 1–2

Kidney & Blood Pressure Research
Introduction: There was limited research on the epidemiology of hyperphosphatemia in early-stage chronic kidney disease (CKD) patients. We aimed to explore the clinical characteristics and prognostic value of hyperphosphatemia in patients with CKD stages
Chao Xie, Qi Gao, Jiao Liu, Licong Su, Mingzhen Pang, Shiyu Zhou, Yaozhong Kong, Sheng Nie, Min Liang   +8 more
doaj   +1 more source

Hyperphosphatemia-Induced Oxidant/Antioxidant Imbalance Impairs Vascular Relaxation and Induces Inflammation and Fibrosis in Old Mice

Antioxidants, 2021
Aging impairs vascular function, but the mechanisms involved are unknown. The aim of this study was to analyze whether aging-related hyperphosphatemia is implied in this effect by elucidating the role of oxidative stress.
Ana Asenjo-Bueno, Elena Alcalde-Estévez, Mariam El Assar, Gemma Olmos, Patricia Plaza, Patricia Sosa, Patricia Martínez-Miguel, María Piedad Ruiz-Torres, Susana López-Ongil   +8 more
doaj   +1 more source

Recombinant human parathyroid hormone in the therapy of hypoparathyroidism [PDF]

Терапевтический архив, 2017
Hypoparathyroidism is an endocrine disease that results from deficiency or complete absence of parathyroid hormone (PTH), a biologically active 84-amino acid polypeptide.
A K Eremkina, N G Mokrysheva, E V Kovaleva, Yu A Krupinova   +3 more
doaj   +1 more source

ICU-Admission Hyperphosphataemia Is Related to Shock and Tissue Damage, Indicating Injury Severity and Mortality in Polytrauma Patients

Diagnostics, 2021
Hyperphosphataemia can originate from tissue ischaemia and damage and may be associated with injury severity in polytrauma patients. In this retrospective, single-centre study, 166 polytrauma patients (injury severity score (ISS) ≥ 16) primarily ...
Christopher Rugg, Mirjam Bachler, Robert Kammerlander, Daniel Niederbrunner, Johannes Bösch, Stefan Schmid, Janett Kreutziger, Mathias Ströhle   +7 more
doaj   +1 more source

Liposomal amphotericin B related late-onset hyperphosphatemia in a pediatric patient with acute myeloid leukemia

, 2022
Introduction: Children with acute myeloid leukemia (AML) are at risk for serious electrolyte abnormalities. Case report: We reported a case of hyperphosphatemia in a child with acute myeloid leukemia who received liposomal amphotericin B (AMBL) for the ...
Aksu, TEKİN, Yalçın, NADİR, Demirkan, Kutay, Çifci, Sude Ayça   +3 more
core   +1 more source

Efficacy of DZ1462, a Novel Sodium-phosphate Transporter Inhibitor, on 5/6 Nephrectomy-induced Hyperphosphatemia Model Rats

Shiyan dongwu yu bijiao yixue, 2022
Objective To study the efficacy of DZ1462, a novel sodium-phosphate transporter inhibitor, on rat hyperphosphatemia models established by 5/6 nephrectomy.Methods Totally 156 rats were randomly selected into four groups.
LU Xiao, ZHANG Lin, JI Hui, JIANG Shanxiang   +3 more
doaj   +1 more source

Human biomarker navigator

iMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li, Qian Zhang, Zijie Wang, Zeping Gui, Jing Liu, Jingda Li, Maojun Jiang, Zukang Chang, Qingqing Han, Bendong Yang, Tariq Saeed, Jun Li, Jinghan Jia, Chenghu Song, Tong Shao, Tianhuan Peng, Xueying Zhang, Pingping Guo, Jun Luo, Gangao Yang, Yuan Wan, Gokhan Zengin, Quan Yuan, Lingru Li, Xiaohui Fan, Yang Luo, Lvyun Zhu, Yanfei Zheng, Wenjun Mao, Wenlong Sun   +29 more
wiley   +1 more source