Results 41 to 50 of about 20,554 (221)

Efficacy of DZ1462, a Novel Sodium-phosphate Transporter Inhibitor, on 5/6 Nephrectomy-induced Hyperphosphatemia Model Rats

Shiyan dongwu yu bijiao yixue, 2022
Objective To study the efficacy of DZ1462, a novel sodium-phosphate transporter inhibitor, on rat hyperphosphatemia models established by 5/6 nephrectomy.Methods Totally 156 rats were randomly selected into four groups.
LU Xiao, ZHANG Lin, JI Hui, JIANG Shanxiang   +3 more
doaj   +1 more source

The Effect of Magnesium Oxide on Hyperphosphatemia in Female Hemodialysis Patients [PDF]

Women’s Health Bulletin, 2014
Background: Hyperphosphatemia is a common problem in hemodialysis patients for which various binders are used to control this problem. Objectives: This study aims to assess the effect of magnesium oxide on controlling serum phosphorus levels and evaluate
Maryam Pakfetrat, Shokouh Sharifpour, Leila Malekmakan, Shahrokh Ezzatzadegan Jahromi, Jamshid Roozbeh, Amir Aslani   +5 more
doaj   +1 more source

Prognostic importance of plasma total magnesium in a cohort of cats with azotemic chronic kidney disease [PDF]

, 2018
BACKGROUND: Hypomagnesemia is associated with increased mortality and renal function decline in humans with chronic kidney disease (CKD). Magnesium is furthermore inversely associated with fibroblast growth factor 23 (FGF23), an important prognostic ...
Andrukhova, Andrukhova, Andrukhova, Angelen, Atarashi, Baaij, Barber, Barber, Barber, Barnes, Barr, Bateman, Blaine, Boyd, Bressendorff, Chakrabarti, Chakrabarti, Cheng, Covic, Cunha, Diaz-Tocados, DiBartola, Elin, Elliott, Geddes, Geddes, Geddes, Geddes, Geiger, Ichihara, Iguchi, Isakova, Ishimura, Ishimura, Jahnen-Dechent, Jensen, Jepson, Joffres, Joosten, Kanbay, Kass, King, Kisters, Laecke, Laecke, Laecke, Lawson, Louvet, Lulich, Ma, Matsuzaki, Matsuzaki, McLeland, Meema, Moe, Moe, Mutsert, Nakayama, Navarro-Gonzalez, Norris, Pearson, Plantinga, Resnick, Ross, Ross, Sakaguchi, Sakaguchi, Sakaguchi, Sakaguchi, Sakaguchi, Sakaguchi, Salem, Satake, Shimada, Slatopolsky, Sontia, Toll, Touyz, Williams, Wooldridge, Yogi, Zhang   +81 more
core   +2 more sources

Mechanism of Action and Clinical Attributes of Auryxia® (Ferric Citrate). [PDF]

, 2019
Chronic kidney disease (CKD) is a major cause of morbidity and premature mortality and represents a significant global public health issue. Underlying this burden are the many complications of CKD, including mineral and bone disorders, anemia, and ...
Bino, Avi, Ganz, Tomas, Salusky, Isidro B   +2 more
core  

Vascular Calcification: Mechanisms, Models, and Therapies

iNew Medicine, EarlyView.
ABSTRACT Vascular calcification represents an active multifactorial process that mirrors several key features of skeletal bone mineralization. Clinically, it is characterized by diminished arterial compliance and increased arterial wall stiffness, both of which serve as independent predictors of significant adverse cardiovascular events.
Wenya Zhu, Shu Yang, Ziyi Chen, Xiaoxiao Yang, Zhen Liang, Yuanli Chen   +5 more
wiley   +1 more source

Cardiovascular problems in dialysis patients - focus on correcting hyperphosphatemia

Медицинский совет, 2020
Mineral-bone disorder in chronic kidney disease (CKD-MBD) is one of the most important factor determining prognosis in dialysis patients. CKD-MBD syndrome occurs at the CKD stage 2 and reaches its maximum in patients with end-stage renal disease ...
A. M. Essaian, A. R. Rind
doaj   +1 more source

Hypophosphatemic effect of niacin extended release in ischemic kidney disease [PDF]

, 2015
Ischemic nephropathy is an emerging cause of end stage renal disease, associated with many co-morbidities especially cardiovascular disease risk and derangement in calcium-phosphorus homeostasis resulting in hyperphosphatemia, influencing bones, a ...
Dawani, Manohar Lal, Mahboob, Tabassum, Yasmeen, Ghazala   +2 more
core   +1 more source

Association between serum α‐Klotho levels and severity of periodontitis in a representative U.S. population

Journal of Periodontology, EarlyView.
Abstract Background Periodontitis, a chronic inflammatory disease, is linked to systemic conditions such as cardiovascular and kidney disease. Serum α‐Klotho, an anti‐aging protein with anti‐inflammatory properties, has been associated with systemic diseases, but its role in periodontitis is unclear.
Hamoun Sabri, Sahar Baniameri, Pranav Kataria, Hend Abulatifa, Parham Hazrati, Hom‐Lay Wang, Muhammad H. A. Saleh   +6 more
wiley   +1 more source

Tumor lysis syndrome in an extraskeletal osteosarcoma: a case report and review of the literature [PDF]

, 2017
BACKGROUND: This case report describes a spontaneous tumor lysis syndrome due to a rare solid tumor. CASE PRESENTATION: A 65-year-old white woman had tumor lysis syndrome, which represent a dangerous oncological emergency.
Giulia Malaguarnera, Michele Malaguarnera, Michele Vecchio, Roberto Madeddu, Saverio Latteri, Vito Emanuele Catania   +5 more
core   +1 more source

Monogenic and syndromic obesity in children: Clinical recognition, genetics, and precision management

Pediatric Investigation, EarlyView.
Monogenic and syndromic obesity in children often arises from defects in the leptin–melanocortin pathway. Understanding these rare genetic causes not only clarifies mechanisms of appetite regulation but also enables precision therapies, offering hope beyond lifestyle interventions.
Hadel Khalil, Eugene Feigin, Hussein Zaitoon   +2 more
wiley   +1 more source