Results 21 to 30 of about 16,312 (208)

Estrogen inhibits renal Na-Pi Co-transporters and improves klotho deficiency-induced acute heart failure

Redox Biology, 2021
Objective and hypothesis: Klotho is an aging-suppressor gene. Mutation of Klotho gene causes hyperphosphatemia and acute heart failure. However, the relationship of hyperphosphatemia and acute heart failure is unclear.
Kai Chen, Zhongjie Sun
doaj   +1 more source

Hyperphosphatemia and Cardiovascular Disease [PDF]

Frontiers in Cell and Developmental Biology, 2021
Hyperphosphatemia or even serum phosphate levels within the “normal laboratory range” are highly associated with increased cardiovascular disease risk and mortality in the general population and patients suffering from chronic kidney disease (CKD). As the kidney function declines, serum phosphate levels rise and subsequently induce the development of ...
Chao Zhou, Zhengyu Shi, Nan Ouyang, Xiongzhong Ruan, Xiongzhong Ruan   +4 more
openaire   +3 more sources

Association between phosphate disturbances and mortality among critically ill patients with sepsis or septic shock

BMC Pharmacology and Toxicology, 2021
Objective The aim of this study is to examine the association of hypophosphatemia and hyperphosphatemia on the first day of ICU admission with mortality in septic critically ill patients. Methods In this retrospective cohort study, all adult patients who
Shmeylan A. Al Harbi, Hasan M. Al-Dorzi, Albatool M. Al Meshari, Hani Tamim, Sheryl Ann I. Abdukahil, Musharaf Sadat, Yaseen Arabi   +6 more
doaj   +1 more source

Association of Serum Phosphate Derangement With Mortality in Patients on Continuous Renal Replacement Therapy

Canadian Journal of Kidney Health and Disease, 2022
Background: There is limited evidence on the association of serum phosphate with mortality in patients receiving continuous renal replacement therapy (CRRT).
Charat Thongprayoon, Yeshwanter Radhakrishnan, Wisit Cheungpasitporn, Tananchai Petnak, Fawad Qureshi, Michael A. Mao, Kianoush B. Kashani   +6 more
doaj   +1 more source

EOS789, pan‐phosphate transporter inhibitor, ameliorates the progression of kidney injury in anti‐GBM‐induced glomerulonephritis rats

Pharmacology Research & Perspectives, 2022
Hyperphosphatemia associated with chronic kidney disease (CKD) not only dysregulates mineral metabolism and bone diseases, but also strongly contributes to the progression of kidney disease itself.
Yoshinori Tsuboi, Yasuhiro Ichida, Atsuko Murai, Akira Maeda, Manami Iida, Atsuhiko Kato, Shuichi Ohtomo, Naoshi Horiba   +7 more
doaj   +1 more source

Prevalence and factors associated with hyperphosphatemia in continuous ambulatory peritoneal dialysis patients: A cross-sectional study

Frontiers in Medicine, 2023
BackgroundHyperphosphatemia remains a major complication in patients with Continuous ambulatory peritoneal dialysis (CAPD) leading to increased morbidity and mortality. However, phosphorus management still has many challenges.ObjectiveThis study aimed to
Xiaojing Yin, Xiaojing Yin, Fan Zhang, Yan Shi   +3 more
doaj   +1 more source

Association between serum fibroblast growth factor‐23 concentration and development of hyperphosphatemia in normophosphatemic dogs with chronic kidney disease

Journal of Veterinary Internal Medicine, 2021
Background Fibroblast growth factor (FGF)‐23 is increased first in the sequence of changes associated with chronic kidney disease (CKD)‐mineral and bone disorder.
Hirosumi Miyakawa, Huai‐Hsun Hsu, Mizuki Ogawa, Ryota Akabane, Yuichi Miyagawa, Naoyuki Takemura   +5 more
doaj   +1 more source

Phosphate intake, hyperphosphatemia, and kidney function [PDF]

, 2022
Phosphate is essential in living organisms and its blood levels are regulated by a complex network involving the kidneys, intestine, parathyroid glands, and the skeleton.
Krapf, Reto, Rubio-Aliaga, Isabel; https://orcid.org/   +1 more
core   +1 more source

Spurious Hyperphosphatemia in a Patient with Multiple Myeloma: A Case Report [PDF]

, 2021
Spurious hyperphosphatemia has been reported periodically in multiple myeloma (MM) patients with paraproteinemia. It is important for clinicians to recognize this phenomenon in order to avoid misdiagnosis and unnecessary treatment for true ...
Rattana Leelawattana, Thakorn Pruktanakul   +1 more
core   +1 more source

An update on tenapanor to treat hyperphosphatemia

, 2022
Hyperphosphatemia is a common feature in patients with chronic kidney disease (CKD), especially in those with end-stage renal disease (ESRD). Commonly, high serum phosphate levels are observed only in later stages of CKD. The control of hyperphosphatemia
Ciceri P., Manna G. L., Cozzolino M., Cianciolo G., Iacovella F., Barbuto S., Galassi A.   +6 more
core   +1 more source