Results 121 to 130 of about 27,643 (258)

Development of Deferoxamine‐Functionalized Cyclodextrin Polymer for Targeted Iron Chelation

open access: yesChemistryOpen, Volume 14, Issue 10, October 2025.
The cyclodextrin polymer is conjugated with 35 deferoxamine units and can form iron(III) complexes. The polymer exhibits significantly lower antiproliferative activity than free deferoxamine. The cyclodextrin polymer with multiple deferoxamine units may present a promising strategy for improving the efficacy of iron chelation therapies.
Roberta Panebianco   +2 more
wiley   +1 more source

Guidelines for writing definitions in ontologies [PDF]

open access: yes, 2017
Ontologies are being used increasingly to promote the reusability of scientific information by allowing heterogeneous data to be integrated under a common, normalized representation. Definitions play a central role in the use of ontologies both by humans
Ruttenberg, Alan   +2 more
core   +1 more source

Systemic Control of Bone Homeostasis by FGF23 Signaling [PDF]

open access: yes, 2016
The regulation of phosphate metabolism as an influence on bone homeostasis is profound. Recent advances in understanding the systemic control of Fibroblast growth factor-23 (FGF23) has uncovered novel effectors of endocrine feedback loops for calcium ...
Clinkenbeard, Erica L.   +1 more
core   +1 more source

Low‐protein diet for chronic kidney disease: Evidence, controversies, and practical guidelines

open access: yesJournal of Internal Medicine, Volume 298, Issue 4, Page 319-335, October 2025.
Abstract The benefits of a low‐protein diet (LPD) in patients with altered kidney function remain controversial. Dietary intake studies are inherently complex and may present numerous biases that must be understood and controlled. Due to these challenges, the scientific evidence in this area remains limited and is subject to dispute.
Denise Mafra   +4 more
wiley   +1 more source

Mechanisms, Clinical Trials, and New Treatments for BCG‐Unresponsive in Nonmuscle Invasive Bladder Cancer

open access: yesCancer Medicine, Volume 14, Issue 18, September 2025.
ABSTRACT Background Bacillus Calmette–Guérin (BCG) is the standard adjuvant therapy for high‐risk non‐muscle invasive bladder cancer (NMIBC), yet treatment failure occurs in 30% to 40% of patients. Those with BCG‐unresponsive disease face a high risk of progression and represent a critical unmet need in urologic oncology.
Xiaotong Huang   +6 more
wiley   +1 more source

Nutrition Support in Acute Kidney Injury [PDF]

open access: yes, 2011
Acute kidney injury is a frequent complication affecting many hospitalized patients and is associated with increased morbidity and mortality. Acute kidney injury often occurs in conjunction with critical illness, which is a hypermetabolic state ...
Alkhunaizi AM   +15 more
core   +2 more sources

Combined effects of hyperphosphatemia and hyperglycemia on the calcification of cultured human aortic smooth muscle cells.

open access: yesExperimental and Therapeutic Medicine, 2018
Vascular calcification (VC) is common in patients with diabetes and/or chronic kidney disease (CKD). It is strongly associated with cardiovascular morbidity and mortality.
Ping Wang   +3 more
semanticscholar   +1 more source

HYPOPARATHYROIDISM: MODERN CONCEPTS AND ANALYSIS OF A CLINICAL CASE

open access: yesАрхивъ внутренней медицины, 2016
The article deals with modern concepts of etiopathogenesis, clinic, diagnosis and treatment of hypoparathyroidism. Pathophysiological mechanisms of clinical symptoms are described. The paper contains the analyzis of autoimmune hypoparathyroidism clinical
L. M. Farkhutdinova   +2 more
doaj   +1 more source

Urinary Fractional Excretion of Phosphorus in Dogs with Spontaneous Chronic Kidney Disease

open access: yesVeterinary Sciences, 2017
The increase of urinary fractional excretion of phosphorus (uFEP) may indicate phosphorus retention before the onset of hyperphosphatemia in the early stages of chronic kidney disease (CKD).
Cínthia Ribas Martorelli   +6 more
doaj   +1 more source

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