Results 121 to 130 of about 27,643 (258)
Development of Deferoxamine‐Functionalized Cyclodextrin Polymer for Targeted Iron Chelation
The cyclodextrin polymer is conjugated with 35 deferoxamine units and can form iron(III) complexes. The polymer exhibits significantly lower antiproliferative activity than free deferoxamine. The cyclodextrin polymer with multiple deferoxamine units may present a promising strategy for improving the efficacy of iron chelation therapies.
Roberta Panebianco +2 more
wiley +1 more source
Guidelines for writing definitions in ontologies [PDF]
Ontologies are being used increasingly to promote the reusability of scientific information by allowing heterogeneous data to be integrated under a common, normalized representation. Definitions play a central role in the use of ontologies both by humans
Ruttenberg, Alan +2 more
core +1 more source
Systemic Control of Bone Homeostasis by FGF23 Signaling [PDF]
The regulation of phosphate metabolism as an influence on bone homeostasis is profound. Recent advances in understanding the systemic control of Fibroblast growth factor-23 (FGF23) has uncovered novel effectors of endocrine feedback loops for calcium ...
Clinkenbeard, Erica L. +1 more
core +1 more source
Low‐protein diet for chronic kidney disease: Evidence, controversies, and practical guidelines
Abstract The benefits of a low‐protein diet (LPD) in patients with altered kidney function remain controversial. Dietary intake studies are inherently complex and may present numerous biases that must be understood and controlled. Due to these challenges, the scientific evidence in this area remains limited and is subject to dispute.
Denise Mafra +4 more
wiley +1 more source
ABSTRACT Background Bacillus Calmette–Guérin (BCG) is the standard adjuvant therapy for high‐risk non‐muscle invasive bladder cancer (NMIBC), yet treatment failure occurs in 30% to 40% of patients. Those with BCG‐unresponsive disease face a high risk of progression and represent a critical unmet need in urologic oncology.
Xiaotong Huang +6 more
wiley +1 more source
Nutrition Support in Acute Kidney Injury [PDF]
Acute kidney injury is a frequent complication affecting many hospitalized patients and is associated with increased morbidity and mortality. Acute kidney injury often occurs in conjunction with critical illness, which is a hypermetabolic state ...
Alkhunaizi AM +15 more
core +2 more sources
H. Ogata +5 more
semanticscholar +1 more source
Vascular calcification (VC) is common in patients with diabetes and/or chronic kidney disease (CKD). It is strongly associated with cardiovascular morbidity and mortality.
Ping Wang +3 more
semanticscholar +1 more source
HYPOPARATHYROIDISM: MODERN CONCEPTS AND ANALYSIS OF A CLINICAL CASE
The article deals with modern concepts of etiopathogenesis, clinic, diagnosis and treatment of hypoparathyroidism. Pathophysiological mechanisms of clinical symptoms are described. The paper contains the analyzis of autoimmune hypoparathyroidism clinical
L. M. Farkhutdinova +2 more
doaj +1 more source
Urinary Fractional Excretion of Phosphorus in Dogs with Spontaneous Chronic Kidney Disease
The increase of urinary fractional excretion of phosphorus (uFEP) may indicate phosphorus retention before the onset of hyperphosphatemia in the early stages of chronic kidney disease (CKD).
Cínthia Ribas Martorelli +6 more
doaj +1 more source

