Results 61 to 70 of about 47,063 (335)
Around 10% to 20% of all cases of acquired hyperpigmentation are drug-induced. The underlying pathogenesis for drug-induced pigmentation includes melanin accumulation, drug accumulation, toxic effects on melanocytes, and hypersecretion of ...
Arunachalam Narayanan+1 more
doaj +1 more source
Objective Raynaud phenomenon (RP) is often the initial clinical manifestation of systemic sclerosis (SSc), but some patients develop other manifestations first. To help elucidate the diversity of SSc presentation in its early stages, we describe the initial clinical manifestations and antinuclear antibody (ANA) profiles of patients in two early SSc ...
Iqtidar Hanif+32 more
wiley +1 more source
Background: Vitamin B12 deficiency leads to a diversity of symptoms and affects many systems. It is often overlooked or sometimes even misdiagnosed in clinical practice.
Jitendra Singh+3 more
doaj +1 more source
ABSTRACT The aim of this study was to characterize the phytochemical profile and potential antiaging and wound‐healing activities of 70% hydroalcoholic crude extract (CHE) from Myrcia neoobscura leaves and its fractions—insoluble (IF), ethyl acetate (EAF), and aqueous (AF)—for use in phytocosmetics for skin application.
Larissa Mascarenhas Krepsky+17 more
wiley +1 more source
A sustainable valorization of chestnut wood waste is proposed through microwave‐assisted subcritical water extraction, optimized via central composite design. The extract is fractionated by membrane filtration and resin purification, enabling water recovery (up to 89%) and obtaining a tannin‐rich fraction, used to synthesize a PVA‐based biopolymer ...
Clelia Aimone+9 more
wiley +1 more source
One of the most common approaches for control of skin pigmentation involves the inhibition of tyrosinase, a copper-containing enzyme which catalyzes the key steps of melanogenesis.
L. Panzella, A. Napolitano
semanticscholar +1 more source
1. Gracilaria is abundantly available red seaweed that has been used as a traditional medicine and food for years and is rich in nutritional value. 2. Gracilaria polysaccharides are sulfated and have been reported to possess various beneficial biological activities and are widely used in food packaging, food formulation, cosmeceutical products, and ...
Amanda Tresiliana Mulio+4 more
wiley +1 more source
Tyrosinase is the rate‐limiting enzyme in melanogenesis. Thiamidol is the most potent inhibitor of human tyrosinase out of 50 000 tested compounds. In clinical studies, it was shown to improve facial hyperpigmentation, post‐inflammatory hyperpigmentation
W. Philipp-Dormston+8 more
semanticscholar +1 more source
Diltiazem-Associated Hyperpigmentation [PDF]
A 59-year-old African American female presented with a one-year history of progressive skin darkening. Her only symptom was mild itching. Medications included diltiazem 180 mg daily (extended release), prescribed three years earlier. Examination revealed blue-gray reticular hyperpigmentation in a photodistributed pattern on the face, neck, “V of the ...
Jesleen Ahluwalia+2 more
openaire +2 more sources
This study built a Wenchang chicken haplotype genome and integrated it with 29 others to create a chicken pangenome atlas. Analysis of 354 chickens revealed 185,205 structural variations (SVs), with one‐third derived from homology‐based and transposable elements.
Lihong Gu+9 more
wiley +1 more source