Early synovial regulatory T cell engagement in posttraumatic osteoarthritis
Objective Posttraumatic osteoarthritis (PTOA) develops despite restoration of joint biomechanics, suggesting that early post‐injury biological processes within the synovium shape disease trajectories. We investigated whether synovial regulatory T (Treg) cells are engaged during the early phase following joint injury and whether experimental enrichment ...
Xueyou Zhang +5 more
wiley +1 more source
Patient-specific implants and virtual surgical planning in surgery-first orthognathic surgery: a case series and review of literature. [PDF]
Ananda N +4 more
europepmc +1 more source
MDL‐800‐induced SIRT6 activation decreases age‐associated osteoarthritis in mice
Objective SIRT6 is a nuclear‐localized histone deacetylase that regulates multiple pathways associated with aging. This study aimed to determine whether systemic administration of a small molecule activator of SIRT6, MDL‐800, decreases the severity of age‐associated osteoarthritis (OA) in mice.
Matheus Moreira Perez +13 more
wiley +1 more source
Cholangioscopy-guided holmium laser ablation for stent-related mucosal hyperplasia causing recurrent cholangitis after endoscopic ultrasound-guided hepaticogastrostomy. [PDF]
Takahashi T +6 more
europepmc +1 more source
Focal Nodular Hyperplasia of the Liver in a Child
We present a case of focal nodular hyperplasia (FNH) of the liver in a 7- year-old girl. The hepatic tumor was found incidentally on physical examination at school.
馮啟彥;黃秀芬;賴鴻緒 +1 more
core
Ceftriaxone‐associated immune haemolytic anaemia: A patient‐level systematic review
Abstract Ceftriaxone can cause acute haemolysis. Its clinical presentation, risk factors, and outcomes remain incompletely characterized. We conducted a systematic review of published cases with patient‐level data, following international guidelines and with registration in PROSPERO (CRD420261338709). Reports were identified through three bibliographic
Sonja Miotti +9 more
wiley +1 more source
Molecular Mechanisms of Intimal Hyperplasia in Saphenous Vein Grafts After Coronary Artery Bypass Grafting. [PDF]
Lazovic DM +10 more
europepmc +1 more source
Mona Mlika,1,2 Walid Gattoufi,1,2 Hazem Zribi,2 Emna Braham,1,2 Adel Marghli,2 Faouzi El Mezni1,21Department of Pathology, Abderrahman Mami Hospital, Tunis, Tunisia; 2Research Unit UR12SP16, Université Tunis El Manar, Faculté de Mé ...
Marghli A +5 more
core
Role of Diagnostic Hysteroscopy in Abnormal Uterine Bleeding, Its Histopathological Correlation, and Associated Metabolic and Endocrine Disorders: A Cross-Sectional Study. [PDF]
Fatima N +3 more
europepmc +1 more source
TCPL, a transfersome with Tween 80 and PEI, enables efficient transdermal siNF‐κB delivery, resolving PEI's toxicity issue. It promotes lysosomal escape and effective transfection, silences NF‐κB, modulates immunity, and inhibits angiogenesis, alleviating psoriasis. With good biocompatibility, TCPL holds strong clinical translation potential. Schematic
Hui Xing +6 more
wiley +1 more source

