Results 1 to 10 of about 412,884 (295)
Of mice and men: Pinpointing species differences in adipose tissue biology
Frontiers in Cell and Developmental Biology, 2022 The prevalence of obesity and metabolic diseases continues to rise, which has led to an increased interest in studying adipose tissue to elucidate underlying disease mechanisms. The use of genetic mouse models has been critical for understanding the role
Emma Börgeson +6 more
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Prognostic value of left ventricular mass index in patients with mild and moderate aortic stenosis
Кардиоваскулярная терапия и профилактика, 2019 Aim. To study the prognostic value of Left Ventricular Mass (LVM) with asymptomatic aortic stenosis (AS) in a long-term outpatient study, as well as the effect of the LVM on major cardiovascular events (CVe).Material and methods.
A. S. Ryazanov +3 more
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Whole-slide image analysis outperforms micrograph acquisition for adipocyte size quantification
Adipocyte, 2020 The distinction between biological processes of adipose tissue expansion is crucial to understanding metabolic derangements, but a robust method for quantifying adipocyte size has yet to be standardized.
Anne S Maguire +5 more
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Biomolecules, 2021 The most common spinal disorder in elderly is lumbar spinal stenosis (LSS), resulting partly from ligamentum flavum (LF) hypertrophy. Its pathophysiology is not completely understood.
Christina C. Westhoff +6 more
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Transcriptomal Insights of Heart Failure from Normality to Recovery
Biomolecules, 2022 Current management of heart failure (HF) is centred on modulating the progression of symptoms and severity of left ventricular dysfunction. However, specific understandings of genetic and molecular targets are needed for more precise treatments.
Mohammed Quttainah +10 more
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Adiponectin for the treatment of diabetic nephropathy [PDF]
The Korean Journal of Internal Medicine, 2019 The metabolic burden caused by hyperglycemia can result in direct and immediate metabolic injuries, such as oxidative stress and tissue inflammation, in the kidney.
Jun Young Lee +4 more
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Poultry Science: Sexual dimorphism is phenotypic differences between males and females in the same species. In general, males in most animals are larger than females at the same age, however, in quail, females have a larger body size with greater muscle mass than males.
Dong-Hwan Kim +3 more
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Mechanisms of IGF-1-Mediated Regulation of Skeletal Muscle Hypertrophy and Atrophy
Cells, 2020 Insulin-like growth factor-1 (IGF-1) is a key growth factor that regulates both anabolic and catabolic pathways in skeletal muscle. IGF-1 increases skeletal muscle protein synthesis via PI3K/Akt/mTOR and PI3K/Akt/GSK3β pathways. PI3K/Akt can also inhibit
Tadashi Yoshida, Patrice Delafontaine
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BiomedicinesThere is ample evidence on the benefit of angiotensin receptor-neprilysin inhibitors (ARNIs) in heart failure, yet data regarding the potential protective action of ARNIs in hypertensive heart disease are sparse. The aim of this study was to show whether
Peter Stanko +8 more
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