Results 31 to 40 of about 422,010 (294)

Molecular Transducers of Human Skeletal Muscle Remodeling under Different Loading States

open access: yesCell Reports, 2020
Summary: Loading of skeletal muscle changes the tissue phenotype reflecting altered metabolic and functional demands. In humans, heterogeneous adaptation to loading complicates the identification of the underpinning molecular regulators.
Tanner Stokes   +13 more
doaj   +1 more source

Weight Pulling: A Novel Mouse Model of Human Progressive Resistance Exercise

open access: yesCells, 2021
This study describes a mouse model of progressive resistance exercise that utilizes a full-body/multi-joint exercise (weight pulling) along with a training protocol that mimics a traditional human paradigm (three training sessions per week, ~8–12 ...
Wenyuan G. Zhu   +8 more
doaj   +1 more source

Cardiac Overexpression of S100A6 Attenuates Cardiomyocyte Apoptosis and Reduces Infarct Size After Myocardial Ischemia‐Reperfusion

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2017
BackgroundCardiomyocyte‐specific transgenic mice overexpressing S100A6, a member of the family of EF‐hand calcium‐binding proteins, develop less cardiac hypertrophy, interstitial fibrosis, and myocyte apoptosis after permanent coronary ligation, findings
Azadeh Mofid   +13 more
doaj   +1 more source

Significance of MEF2C and RUNX3 Regulation for Endochondral Differentiation of Human Mesenchymal Progenitor Cells

open access: yesFrontiers in Cell and Developmental Biology, 2020
Guiding progenitor cell development between chondral versus endochondral pathways is still an unachieved task of cartilage neogenesis, and human mesenchymal progenitor cell (MPC) chondrogenesis is considered as a valuable model to better understand ...
Simon I. Dreher   +4 more
doaj   +1 more source

Emerging Roles of Neuronal Ca2+ Sensor-1 in Cardiac and Neuronal Tissues: A Mini Review

open access: yesFrontiers in Molecular Neuroscience, 2019
The EF-hand calcium (Ca2+)-binding protein, neuronal Ca2+ sensor-1 (NCS-1/frequenin), is predominantly expressed in neuronal tissues and plays a crucial role in neuronal functions, including synaptic transmission and plasticity.
Tomoe Y. Nakamura   +4 more
doaj   +1 more source

Prostatic Hypertrophy [PDF]

open access: yesThe American Journal of the Medical Sciences, 1898
n ...
openaire   +2 more sources

Adenotonsillar Hypertrophy in Pre-School Children with Sickle Cell Disease and Diagnostic Accuracy of the Sleep Disturbance Scale for Children

open access: yesInternational Archives of Otorhinolaryngology, 2018
Introduction Adenotonsillar hypertrophy is more common in children with sickle cell disease, and can lead to sleep-disordered breathing. Objectives To determine the frequency of adenotonsillar hypertrophy in pre-school children with sickle ...
Carlos Rodolfo Tavares de Góis   +4 more
doaj   +1 more source

EXPLORING AND MODELING CARDIAC HYPERTROPHY USING H9C2 VENTRICULAR CELLS EXPOSED TO ANGIOTENSIN-II OR LIPOPOLYSACCHARIDE FOR STUDYING HEME METABOLISM REGULATION

open access: yes, 2023
A thesis describing the ineffectiveness of using H9c2 ventricular cells as a model of cellular hypertrophy for pharmacological testing.Background: Hypertrophy occurs in heart failure with preserved ejection fraction (HFpEF).
Kim, Min Ji
core  

1,25(OH)2 vitamin D3, and retinoic acid antagonize endothelin-stimulated hypertrophy of neonatal rat cardiac myocytes. [PDF]

open access: yes, 1996
1,25 (OH)(2) Vitamin D-3 (VD3) and retinoic acid (RA) function as ligands for nuclear receptors which regulate transcription, Though the cardiovascular system is not thought to represent a classical target for these ligands, it is clear that both cardiac
Gardner, D. G.   +7 more
core   +1 more source

Developmental Aspects of Cardiac Adaptation to Increased Workload

open access: yesJournal of Cardiovascular Development and Disease, 2023
The heart is capable of extensive adaptive growth in response to the demands of the body. When the heart is confronted with an increased workload over a prolonged period, it tends to cope with the situation by increasing its muscle mass.
Bohuslav Ostadal   +6 more
doaj   +1 more source

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