Results 21 to 30 of about 383,230 (309)
Quantitative morphology of renal cortical structures during compensatory hypertrophy [PDF]
, 1998 The compensatory hypertrophy in different renal cortical structures was studied in rats 10 and 21 days after unilateral nephrectomy (UNX). Quantitative morphological/stereological analysis revealed significant increases in total renal cortical volume ...
Giebisch, Gerhard +4 more
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Cells, 2019 Connexin 43 (Cx43) is essential for cardiac electrical coupling, but its effects on myocardial fibrosis is controversial. Here, we analyzed the role of Cx43 in myocardial fibrosis caused by angiotensin II (AngII) using Cx43fl/fl and Cx43Cre-ER(T)/fl ...
Laura Valls-Lacalle +7 more
doaj +1 more source
The transcriptional coactivator PGC-1α is dispensable for chronic overload-induced skeletal muscle hypertrophy and metabolic remodeling [PDF]
, 2013 Skeletal muscle mass loss and dysfunction have been linked to many diseases. Conversely, resistance exercise, mainly by activating mammalian target of rapamycin complex 1 (mTORC1), promotes skeletal muscle hypertrophy and exerts several therapeutic ...
Handschin, Christoph +9 more
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Requirement of myomaker-mediated stem cell fusion for skeletal muscle hypertrophy
eLife, 2017 Fusion of skeletal muscle stem/progenitor cells is required for proper development and regeneration, however the significance of this process during adult muscle hypertrophy has not been explored.
Qingnian Goh, Douglas P Millay
doaj +1 more source
The Incidence and Clinical Relevance of Graft Hypertrophy After Matrix-Based Autologous Chondrocyte Implantation [PDF]
, 2011 Background: Graft hypertrophy is the most common complication of periosteal autologous chondrocyte implantation (p-ACI). Purpose: The aim of this prospective study was to analyze the development, the incidence rate, and the persistence of graft ...
Matthias F. Pietschmann +13 more
core +1 more source
Frontiers in Physiology, 2018 Background: Yiqifumai Injection (YQFM) is clinically used to treat various cardiovascular diseases including chronic heart failure (CHF). The efficacy of YQFM for treating heart failure has been suggested, but the mechanism of action for pharmacological ...
Yu Zhao +7 more
doaj +1 more source
Frontiers in Pharmacology, 2018 Fructus Ligustri Lucidi (FLL) has been widely used as a traditional Chinese medicine (TCM) for treating soreness and weakness of waist and knees. It has potential for treating OA owing to its kidney-tonifying activity with bone-strengthening effects, but
Bo Yan +12 more
doaj +1 more source
Electrocardiographic (ECG) criteria for determining left ventricular mass in young healthy men; data from the LARGE Heart study [PDF]
, 2009 Background: Doubts remain over the use of the ECG in identifying those with increased left ventricular (LV) mass. This is especially so in young individuals, despite their high prevalence of ECG criteria for LV hypertrophy.
Syed Sohaib +12 more
core +1 more source
Human stem cell-based in vitro model of cardiac hypertrophy [PDF]
, 2022 Cardiac hypertrophy is an important and independent risk factor for the development of cardiomyopathy that may lead to heart failure. To accelerate the development of new and improved treatment options, relevant disease models that can be used to ...
Johansson, Markus
core +1 more source
Role of Foxo1 gene expression in mechanism of antihypertrophic action of metformin in cardiomyocytes
Mìžnarodnij Endokrinologìčnij Žurnal, 2018 Background. Diabetic cardiomyopathy is the leading cause of mortality in patients with type 2 diabetes mellitus. Hypertrophy of cardiomyocytes is one of the main pathomorphological signs of diabetic cardiomyopathy development.
N.V. Pasiechko +3 more
doaj +1 more source