Results 21 to 30 of about 412,884 (295)

MEF2 and the Right Ventricle: From Development to Disease

open access: yesFrontiers in Cardiovascular Medicine, 2019
Pulmonary arterial hypertension is a progressive and ultimately life-limiting disease in which survival is closely linked to right ventricular function.
Katharine R. Clapham   +5 more
doaj   +1 more source

N-Acetylcysteine, an ROS Inhibitor, Alleviates the Pathophysiology of Hyperthyroidism-Induced Cardiomyopathy via the ROS/Ca2+ Pathway

open access: yesBiomolecules, 2022
Hyperthyroidism is common and can induce cardiomyopathy, but there is no effective therapeutic strategy. The purpose of this study was to investigate the molecular mechanism of hyperthyroidism-induced cardiomyopathy (HTC) and the effect of N ...
Mengni Bao   +8 more
doaj   +1 more source

Mаsseter muscle hypertrophy in dentistry [PDF]

open access: yes, 2018
Masseter hypertrophy (MH) is rare, asymptomatic condition with unexplained etiology. The main finding is unilateral or bilateral benign enlargement of masseter muscles, which results in a pronounced contour of the face and/or in the angle of the lower ...
Vasileva, Radostina; Medical University of Varna
core   +1 more source

Quantitative morphology of renal cortical structures during compensatory hypertrophy [PDF]

open access: yes, 1998
The compensatory hypertrophy in different renal cortical structures was studied in rats 10 and 21 days after unilateral nephrectomy (UNX). Quantitative morphological/stereological analysis revealed significant increases in total renal cortical volume ...
Giebisch, Gerhard   +4 more
core   +1 more source

Opposite Effects of Moderate and Extreme Cx43 Deficiency in Conditional Cx43-Deficient Mice on Angiotensin II-Induced Cardiac Fibrosis

open access: yesCells, 2019
Connexin 43 (Cx43) is essential for cardiac electrical coupling, but its effects on myocardial fibrosis is controversial. Here, we analyzed the role of Cx43 in myocardial fibrosis caused by angiotensin II (AngII) using Cx43fl/fl and Cx43Cre-ER(T)/fl ...
Laura Valls-Lacalle   +7 more
doaj   +1 more source

Requirement of myomaker-mediated stem cell fusion for skeletal muscle hypertrophy

open access: yeseLife, 2017
Fusion of skeletal muscle stem/progenitor cells is required for proper development and regeneration, however the significance of this process during adult muscle hypertrophy has not been explored.
Qingnian Goh, Douglas P Millay
doaj   +1 more source

The transcriptional coactivator PGC-1α is dispensable for chronic overload-induced skeletal muscle hypertrophy and metabolic remodeling [PDF]

open access: yes, 2013
Skeletal muscle mass loss and dysfunction have been linked to many diseases. Conversely, resistance exercise, mainly by activating mammalian target of rapamycin complex 1 (mTORC1), promotes skeletal muscle hypertrophy and exerts several therapeutic ...
Handschin, Christoph   +9 more
core   +1 more source

Analysis of microRNA Expression Profiles Induced by Yiqifumai Injection in Rats with Chronic Heart Failure

open access: yesFrontiers in Physiology, 2018
Background: Yiqifumai Injection (YQFM) is clinically used to treat various cardiovascular diseases including chronic heart failure (CHF). The efficacy of YQFM for treating heart failure has been suggested, but the mechanism of action for pharmacological ...
Yu Zhao   +7 more
doaj   +1 more source

The Incidence and Clinical Relevance of Graft Hypertrophy After Matrix-Based Autologous Chondrocyte Implantation [PDF]

open access: yes, 2011
Background: Graft hypertrophy is the most common complication of periosteal autologous chondrocyte implantation (p-ACI). Purpose: The aim of this prospective study was to analyze the development, the incidence rate, and the persistence of graft ...
Matthias F. Pietschmann   +13 more
core   +1 more source

Intra-Articular Injection of Fructus Ligustri Lucidi Extract Attenuates Pain Behavior and Cartilage Degeneration in Mono-Iodoacetate Induced Osteoarthritic Rats

open access: yesFrontiers in Pharmacology, 2018
Fructus Ligustri Lucidi (FLL) has been widely used as a traditional Chinese medicine (TCM) for treating soreness and weakness of waist and knees. It has potential for treating OA owing to its kidney-tonifying activity with bone-strengthening effects, but
Bo Yan   +12 more
doaj   +1 more source

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