Frontiers in Pharmacology, 2018 Fructus Ligustri Lucidi (FLL) has been widely used as a traditional Chinese medicine (TCM) for treating soreness and weakness of waist and knees. It has potential for treating OA owing to its kidney-tonifying activity with bone-strengthening effects, but
Bo Yan +12 more
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Macro, Micro, and Molecular. Changes of the Osteochondral Interface in Osteoarthritis Development
Frontiers in Cell and Developmental Biology, 2021 Osteoarthritis (OA) is a long-term condition that causes joint pain and reduced movement. Notably, the same pathways governing cell growth, death, and differentiation during the growth and development of the body are also common drivers of OA.
Xiwei Fan +6 more
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Electrocardiographic (ECG) criteria for determining left ventricular mass in young healthy men; data from the LARGE Heart study [PDF]
, 2009 Background: Doubts remain over the use of the ECG in identifying those with increased left ventricular (LV) mass. This is especially so in young individuals, despite their high prevalence of ECG criteria for LV hypertrophy.
Syed Sohaib +12 more
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Role of Foxo1 gene expression in mechanism of antihypertrophic action of metformin in cardiomyocytes
Mìžnarodnij Endokrinologìčnij Žurnal, 2018 Background. Diabetic cardiomyopathy is the leading cause of mortality in patients with type 2 diabetes mellitus. Hypertrophy of cardiomyocytes is one of the main pathomorphological signs of diabetic cardiomyopathy development.
N.V. Pasiechko +3 more
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Frontiers in Cell and Developmental Biology, 2019 A major problem with chondrocytes derived in vitro from stem cells is undesired hypertrophic degeneration, to which articular chondrocytes (ACs) are resistant. As progenitors of all adult tissues, induced pluripotent stem cells (iPSCs) are in theory able
Solvig Diederichs +3 more
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Adaptations to Post-exercise Cold Water Immersion: Friend, Foe, or Futile?
Frontiers in Sports and Active Living, 2021 In the last decade, cold water immersion (CWI) has emerged as one of the most popular post-exercise recovery strategies utilized amongst athletes during training and competition.
Mohammed Ihsan +3 more
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The effect of exercise training on transverse tubules in normal, remodeled, and reverse remodeled hearts [PDF]
, 2011 The response of transverse (T)-tubules to exercise training in health and disease remains unclear. Therefore, we studied the effect of exercise training on the density and spacing of left ventricle cardiomyocyte T-tubules in normal and remodeled hearts ...
Kemi, Ole J. +17 more
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Determination of L-Type Calcium Current in the Primary Hypertrophied Left Ventricular Cardiomyocytes of Hypertrophy Heart Rats/HHR [PDF]
, 2009 Background: The molecular mechanisms responsible for electromechanical derangements found in primary left ventricular (LV) hypertrophy have not been clearly elucidated.
Danes, Vennetia R.
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Concentric left ventricular remodeling and aortic stiffness: a comparison of obesity and hypertension. [PDF]
, 2013 BACKGROUND: Increased thoracic ascending aortic stiffness is thought to contribute to concentric left ventricular hypertrophy and increased mortality, a pattern seen in hypertension.
Francis, JM +15 more
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