Results 11 to 20 of about 320,824 (239)
Cells, 2019 Connexin 43 (Cx43) is essential for cardiac electrical coupling, but its effects on myocardial fibrosis is controversial. Here, we analyzed the role of Cx43 in myocardial fibrosis caused by angiotensin II (AngII) using Cx43fl/fl and Cx43Cre-ER(T)/fl ...
Laura Valls-Lacalle +7 more
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Requirement of myomaker-mediated stem cell fusion for skeletal muscle hypertrophy
eLife, 2017 Fusion of skeletal muscle stem/progenitor cells is required for proper development and regeneration, however the significance of this process during adult muscle hypertrophy has not been explored.
Qingnian Goh, Douglas P Millay
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Frontiers in Physiology, 2018 Background: Yiqifumai Injection (YQFM) is clinically used to treat various cardiovascular diseases including chronic heart failure (CHF). The efficacy of YQFM for treating heart failure has been suggested, but the mechanism of action for pharmacological ...
Yu Zhao +7 more
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Frontiers in Pharmacology, 2018 Fructus Ligustri Lucidi (FLL) has been widely used as a traditional Chinese medicine (TCM) for treating soreness and weakness of waist and knees. It has potential for treating OA owing to its kidney-tonifying activity with bone-strengthening effects, but
Bo Yan +12 more
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Macro, Micro, and Molecular. Changes of the Osteochondral Interface in Osteoarthritis Development
Frontiers in Cell and Developmental Biology, 2021 Osteoarthritis (OA) is a long-term condition that causes joint pain and reduced movement. Notably, the same pathways governing cell growth, death, and differentiation during the growth and development of the body are also common drivers of OA.
Xiwei Fan +6 more
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Role of Foxo1 gene expression in mechanism of antihypertrophic action of metformin in cardiomyocytes
Mìžnarodnij Endokrinologìčnij Žurnal, 2018 Background. Diabetic cardiomyopathy is the leading cause of mortality in patients with type 2 diabetes mellitus. Hypertrophy of cardiomyocytes is one of the main pathomorphological signs of diabetic cardiomyopathy development.
N.V. Pasiechko +3 more
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Frontiers in Cell and Developmental Biology, 2019 A major problem with chondrocytes derived in vitro from stem cells is undesired hypertrophic degeneration, to which articular chondrocytes (ACs) are resistant. As progenitors of all adult tissues, induced pluripotent stem cells (iPSCs) are in theory able
Solvig Diederichs +3 more
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Adaptations to Post-exercise Cold Water Immersion: Friend, Foe, or Futile?
Frontiers in Sports and Active Living, 2021 In the last decade, cold water immersion (CWI) has emerged as one of the most popular post-exercise recovery strategies utilized amongst athletes during training and competition.
Mohammed Ihsan +3 more
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Molecular Transducers of Human Skeletal Muscle Remodeling under Different Loading States
Cell Reports, 2020 Summary: Loading of skeletal muscle changes the tissue phenotype reflecting altered metabolic and functional demands. In humans, heterogeneous adaptation to loading complicates the identification of the underpinning molecular regulators.
Tanner Stokes +13 more
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