Brca2 and Trp53 deficiency cooperate in the progression of mouse prostate tumourigenesis. [PDF]
Epidemiological studies have shown that one of the strongest risk factors for prostate cancer is a family history of the disease, suggesting that inherited factors play a major role in prostate cancer susceptibility.
Ashworth, Alan+4 more
core +3 more sources
INFLUENCE OF THE CTLA-4 (RS231775) GENE POLYMORPHISM ON THE DEGREE OF THE THYROID GLAND ENLARGEMENT IN PATIENTS OPERATED FOR NODULAR GOITER SECONDARY TO AUTOIMMUNE THYROIDITIS [PDF]
Objectives: To analyze the influence of the CTLA-4(+49G/A)rs231775 gene polymorphism on the degree of thyroid gland enlargement in patients operated for nodular goiter secondary to autoimmune thyroiditis (NGAIT) and thyroid adenomas (TA).
Michael I. Sheremet+11 more
doaj
Aim: Atypical adenomatous hyperplasia (AAH) is a small glandular proliferation that has histological similarities with Gleason grade 1 and 2 prostatic adenocarcinoma (PACG1,2).
Ahmet Midi+3 more
doaj +1 more source
Normocalcemic non-renal hyperparathyroidism
Parathyroid hormone (PTH) is produced by the parathyroid glands, which are the main regulators of calcium and phosphorus metabolism. Hyperparathyroidism is a clinical condition associated with an increase in serum PTH content.
O.V. Kaminskyi, Yu.O. Kaminskа
doaj +1 more source
Progestogens are widely used for the conservative treatment of endometrial hyperplasia and early endometrial cancer. Nevertheless, they do not achieve the regression in all cases. Although several immunohistochemical markers have been assessed to predict
A. Travaglino+6 more
semanticscholar +1 more source
Preleukemia: hematological disorders prior to onset of leukemia [PDF]
Published data on Japanese leukemia patients with a preleukemic hematological disorder were assessed. The reexamined cases were from the "Japona Centra Revuo Medicina" reported during the period from 1952 to 1971.
Hiraki, Kiyoshi+5 more
core +1 more source
Idiopathic noncirrhotic portal hypertension: current perspectives [PDF]
The term idiopathic noncirrhotic portal hypertension (INCPH) has been recently proposed to replace terms, such as hepatoportal sclerosis, idiopathic portal hypertension, incomplete septal cirrhosis, and nodular regenerative hyperplasia, used to describe ...
D'AMATI, Giulia+5 more
core +1 more source
Pigmentary keratitis and mixed chromatophoroma in a betta fish (Betta splendens)
Graphical Abstract This clinical case report describes a <1 year old betta fish that developed pigmentary keratitis, anterior uveitis, and a mixed chromatophoroma that led to the patient's death. A review of available anecdotal and scientific literature suggests that there may have been a genetic cause for these health problems.
Alicia McLaughlin+3 more
wiley +1 more source
Asymptomatic endometrial thickening in postmenopausal women: predictor of malignant pathology?
It is not standardised what is the endometrial thickness that discriminates between normal and potentially malignant. The objective of this study was to determine the endometrial thickness cut-off point from which the risk of endometrial cancer (EC ...
Alba María Cruz García+8 more
doaj +1 more source
PEA‐15 (Phosphoprotein Enriched in Astrocytes 15) Is a Protective Mediator in the Vasculature and Is Regulated During Neointimal Hyperplasia [PDF]
This work was supported by a grant from the Medical Research Council, UK (MR/K012789/1).
Gibson, George+4 more
core +2 more sources