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Hyperpolarizing factors

Coronary Artery Disease, 1991
This review addresses the recent emergence in the literature of a putative factor called endothelium-derived hyperpolarizing factor (EDHF). The EDHF is characterized by the fact that it is emitted from the endothelium and hyperpolarizes the arterial smooth muscles.
Beny, Jean-Louis   +1 more
openaire   +2 more sources

Hyperpolarizing Water with Parahydrogen

ChemPhysChem, 2017
AbstractStudies of water‐based systems are of fundamental interest for nuclear magnetic resonance (NMR) and magnetic resonance imaging (MRI) as water is the most abundant and important medium for global living. Hence, increasing the polarization of water and dissolved compounds is particularly attractive for biomedical applications such as ...
Sören Lehmkuhl   +6 more
openaire   +3 more sources

Adaptation by Hyperpolarization

Science, 1997
Adaption to external stimuli prevents us from being overwhelmed by the constant bombardment of our senses: A noxious odor, immediately repulsive, becomes hardly noticeable; after a time, the sound of traffic is no longer annoying. A report in this week's issue by Carandini and Ferster (p.
openaire   +2 more sources

Quantification in Hyperpolarized NMR

The Journal of Physical Chemistry Letters, 2016
Quantitative aspects of hyperpolarized NMR are analyzed in the present work, and it is shown theoretically and experimentally that measured "apparent" signal enhancements could deviate significantly from real enhancements of polarization. Expressions are given as a function of spin count to deduce real enhancements from measured "apparent" enhancements,
Arnab, Dey, Narayanan, Chandrakumar
openaire   +2 more sources

Hyperpolarized Molecules in Solution

2011
Hyperpolarization is a technique to enhance the nuclear polarization and thereby increase the available signal in magnetic resonance (MR). This chapter provides an introduction to the concept of hyperpolarization as well as an overview of dynamic nuclear polarization (DNP) and para-hydrogen induced polarization (PHIP), two methods used to generate ...
Jan Henrik, Ardenkjaer-Larsen   +3 more
openaire   +2 more sources

Hyperpolarized 83Kr MRI of lungs

Journal of Magnetic Resonance, 2008
Hyperpolarized (hp) (83)Kr (spin I=9/2) is a promising gas-phase contrast agent that displays sensitivity to the surface chemistry, surface-to-volume ratio, and surface temperature of the surrounding environment. This proof-of-principle study demonstrates the feasibility of ex vivo hp (83)Kr magnetic resonance imaging (MRI) of lungs using natural ...
Zackary I, Cleveland   +5 more
openaire   +2 more sources

Endothelium-dependent hyperpolarizations: the history

Pharmacological Research, 2004
Endothelial cells control the tone and the growth of the underlying vascular smooth muscle by releasing Nitric Oxide (NO). This introduction summarizes the early experiments which first suggested and then demonstrated the existence of an alternative pathway, endothelium-dependent hyperpolarization.
openaire   +4 more sources

Hyperpolarized Gas Imaging

1996
The sections in this article are 1 Introduction 2 The Gas Polarization Process 3 Imaging of Polarized Gas 4 Conclusions 5 Biographical Sketch Related ...
James R. MacFall, Bastiaan Driehuys
openaire   +1 more source

Dynamic Nuclear Hyperpolarization in Liquids

2011
Nuclear magnetic resonance (NMR) spectroscopy is a broadly used analytical method with major applications in chemistry, biochemistry and medicine. Key applications include structural analysis of small molecules, metabolites, larger biomolecules such as proteins, RNA and DNA, and applications in material science.
openaire   +2 more sources

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