Results 41 to 50 of about 22,618 (258)

Gut microbial‐derived 3,4‐dihydroxyphenylacetic acid ameliorates reproductive phenotype of polycystic ovary syndrome

iMeta, EarlyView.
By integrating multi‐level and multi‐omics analyses, we identify 3,4‐dihydroxyphenylacetic acid (DHPAA), a gut microbiota‐derived degradation product of dietary flavonoids, as a key bioactive end‐product responsible for the beneficial effects against polycystic ovary syndrome (PCOS).
Pan Li, Li Xie, Huimin Zheng, Yinglin Feng, Feihong Mai, Wenli Tang, Jiajia Wang, Zixin Lan, Shuaijun Lv, Thisun Jayawardana, Sabrina Koentgen, Shuangbin Xu, Zhengwei Wan, Yunjie Chen, Haiyan Xu, Sj Shen, Fan Zhang, Yuanhao Yang, Georgina Hold, Fangjie He, Emad M. El‐Omar, Guangchuang Yu, Xia Chen   +22 more
wiley   +1 more source

Importance of macroprolactinemia in hyperprolactinemia

European Journal of Obstetrics & Gynecology and Reproductive Biology, 2014
Macroprolactin is an antigen-antibody complex of higher molecular mass than prolactin (>150kDa), consisting of monomeric prolactin and immunoglobulin G. The term 'macroprolactinemia' is used when the concentration of macroprolactin exceeds 60% of the total serum prolactin concentration determined by polyethylene glycol precipitation.
Kasum, Miro, Pavičić-Baldani, Dinka, Stanić, Patrik, Orešković, Slavko, Šarić, Jakov-Marko, Blajić, Jozo, Juras, Josip   +6 more
openaire   +4 more sources

Treatment of hyperprolactinemia in women: A Position Statement from the Brazilian Federation of Gynecology and Obstetrics Associations (Febrasgo) and the Brazilian Society of Endocrinology and Metabolism (SBEM)

Archives of Endocrinology and Metabolism
Dopamine agonists are the first line of treatment for patients with symptomatic hyperprolactinemia due to prolactinomas and in those with idiopathic hyperprolactinemia. Treatment with these agents is effective in 80%-90% of the cases.
Cristina Laguna Benetti-Pinto, Andrea Prestes Nácul, Ana Carolina Japur de Sá Rosa-e-Silva, Gustavo Arantes Rosa Maciel, Vania dos Santos Nunes Nogueira, Paula Condé Lamparelli Elias, Manoel Martins, Leandro Kasuki, Heraldo Mendes Garmes, Andrea Glezer   +9 more
doaj   +1 more source

Radiological features of breast benign lesions in patients with hyperprolactinemia [PDF]

Archive of Oncology, 2007
Background: The study was conducted to determine whether prolactin (PRL) influences radiological features of benign breast lesions. Methods: During the 4-year period, we observed 50 patients with nipple discharge: 23 with normal serum prolactin levels ...
Radojković Danijela, Antić Slobodan, Pešić Milica, Radojković Milan, Bašić Dijana, Rađenović-Petković Tatjana   +5 more
doaj   +1 more source

Hyperprolactinemia and estimated dopamine D2 receptor occupancy in patients with schizophrenia : analysis of the CATIE data [PDF]

, 2013
Background Large-scale data are still lacking on the relationship between serum prolactin concentration and dopamine D2 receptor occupancy in patients with schizophrenia treated with antipsychotics.
Bies, Robert R., Graff-Guerrero, Ariel, Mamo, David, Mimura, Masaru, Pollock, Bruce G., Suzuki, Takefumi, Tsuboi, Takashi, Uchida, Hiroyuki   +7 more
core   +1 more source

Molecular Tools to Study and Control Dopaminergic Neurotransmission With Light

Medicinal Research Reviews, EarlyView.
ABSTRACT Dopaminergic neurotransmission is involved in several important brain functions, such as motor control, learning, reward‐motivated behavior, and emotions. Dysfunctions of dopaminergic system may lead to the development of various neurological and psychiatric disorders, like Parkinson's disease, schizophrenia, depression, and addictions ...
Galyna Maleeva, Carlo Matera, Silvia Roda, Alessio Colleoni, Marco De Amici, Pau Gorostiza   +5 more
wiley   +1 more source

Diagnosis of hyperprolactinemia in women: A Position Statement from the Brazilian Federation of Gynecology and Obstetrics Associations (Febrasgo) and the Brazilian Society of Endocrinology and Metabolism (SBEM)

Archives of Endocrinology and Metabolism
Hyperprolactinemia is a frequent cause of menstrual irregularity, galactorrhea, hypogonadism, and infertility. The most common etiologies of hyperprolactinemia can be classified as physiological, pharmacological, and pathological.
Andrea Glezer, Heraldo Mendes Garmes, Leandro Kasuki, Manoel Martins, Paula Condé Lamparelli Elias, Vania dos Santos Nunes Nogueira, Ana Carolina Japur de Sá Rosa-e-Silva, Gustavo Arantes Rosa Maciel, Cristina Laguna Benetti-Pinto, Andrea Prestes Nácul   +9 more
doaj   +1 more source

Neuroendocrine Regulation of Metabolism [PDF]

, 2016
Given the current environment in most developed countries, it is a challenge to maintain a good balance between calories consumed and calories burned, although maintenance of metabolic balance is key to good health. Therefore, understanding how metabolic
Becu Villalobos, D., Coirini, Hector, Cornejo, María Paula, Elias, C. F., Hentges, S.T., Maliqueo, M.   +5 more
core   +3 more sources

Kisspeptin as a test of hypothalamic dysfunction in pubertal and reproductive disorders

Andrology, EarlyView.
Abstract The hypothalamic–pituitary–gonadal axis is regulated by the gonadotropin‐releasing hormone pulse generator in the hypothalamus. This is comprised of neurons that secrete kisspeptin in a pulsatile manner to stimulate the release of GnRH, and, in turn, downstream gonadotropins from the pituitary gland, and subsequently sex steroids and ...
Aureliane C. S. Pierret, Aaran H. Patel, Elisabeth Daniels, Alexander N. Comninos, Waljit S. Dhillo, Ali Abbara   +5 more
wiley   +1 more source

Teratogenicity and hyperprolactinemia

Indian Journal of Psychiatry, 2009
Byline: Chittaranjan. Andrade CME Questions A) Drugs should be prescribed with caution to women of childbearing age because of the risk of teratogenicity, should conception occur during treatment; this concern is particularly important when prescribing drugs that will be required for long periods, such as in the maintenance therapy of epilepsy, bipolar
openaire   +3 more sources