Results 91 to 100 of about 149 (148)
Endogenous Ethanol Production in the Human Alimentary Tract: A Literature Review
ABSTRACT Endogenous ethanol production, or auto‐brewery syndrome (ABS), is a rare condition of the human alimentary canal that results in intoxication without alcohol consumption. Despite its clinical significance, ABS remains largely undiagnosed because of a lack of awareness among clinicians.
Renee Stamation
wiley +1 more source
ABSTRACT Background Fragile X Syndrome (FXS) is a genetic disorder caused by the lack of FMRP, a crucial protein for brain development and function. FMR1 mutations are categorized into premutation and full mutation (FXSFull), with somatic mosaicism (FXSMos) modulating the FXS phenotype.
Fabiola Spolaor+8 more
wiley +1 more source
ABSTRACT Background Temporomandibular joint osteoarthritis (TMJ‐OA) presents a significant clinical challenge, marked by limited therapeutic options and variable patient responses. While regenerative therapies show promising results, conventional clinical trial methodologies often fail to demonstrate a significant clinical difference, largely due to ...
Ricardo de Souza Tesch+4 more
wiley +1 more source
Psychophysical changes after total sleep deprivation and experimental muscle pain
Summary Sleep disturbances exacerbate chronic pain, increase psychological load, and increase inflammation. Delayed onset muscle soreness (DOMS) mimics aspects of chronic pain, predominantly affecting peripheral pain mechanisms, while experimental sleep provocations have been shown to impact central pain mechanisms.
Emma Hertel+5 more
wiley +1 more source
Clinical Practice Guidelines and Food‐Based Dietary Guidelines differ in methodological quality, but their recommendations on Early Childhood Allergy Prevention are fairly consistent. However, low transparency in guideline development can still lead to reduced trust in the guideline, low implementation and insufficient adherence to the recommendations.
Katharina Sieferle, Eva M. Bitzer
wiley +1 more source
Abstract In contemporary Singaporean sociopolitical discourse, comparisons with the West—particularly the USA and the UK—have become pervasive across a wide range of critical social issues. These comparisons often serve to reinforce the political positions of the Singaporean state by contrasting them with perceived shortcomings in the Western world ...
Wee Yang Gelles‐Soh
wiley +1 more source
Neuropsychiatric Manifestations in Breath‐Hold Divers and the Folklore of Tomokazuki
ABSTRACT Diving can affect neuropsychiatric functions. Previous studies of Taravana syndrome in Polynesian pearl divers, which have similarities to decompression illness following breath‐hold diving, and of Chiyamai in Japanese breath‐hold divers, which have symptoms like panic disorder, show what modern medicine can learn from the wisdom of tradition.
Tomoko Komagamine+2 more
wiley +1 more source
Enteric neuropathy and the vagus nerve: Therapeutic implications
Abstract Enteric neuropathies are characterized by abnormalities of gut innervation, which includes the enteric nervous system, inducing severe gut dysmotility among other dysfunctions. Most of the gastrointestinal tract is innervated by the vagus nerve, the efferent branches of which have close interconnections with the enteric nervous system and ...
Bruno Bonaz
wiley +1 more source
Genomic stress in diseases stemming from defects in the second brain
The enteric nervous system, a.k.a., second brain, is subject to a range of genotoxic exposures that include intrinsic oxidative stress and extrinsic agents associated with ingested foods, inflammation, and dysbiosis. Resulting DNA damage, if left unrepaired, can induce cell dysfunction or death, resulting in gut abnormalities and enteric neuropathy ...
Lobke Marie M. Mombeek+2 more
wiley +1 more source
Evidence‐based review and frontiers of migraine therapy
Abstract Background Cyclic vomiting syndrome (CVS) is identified as one of the “episodic syndromes that may be associated with migraine,” along with benign paroxysmal torticollis, benign paroxysmal vertigo, and abdominal migraine. It has been proposed that CVS and migraine may share pathophysiologic mechanisms of hypothalamic activation and altered ...
Kaitlin A. Greene+2 more
wiley +1 more source