Chemotherapy‐induced peripheral neuropathy (CIPN) remains a major clinical challenge, with central sensitization considered an important pathological mechanism in its occurrence and persistence. This review focuses on spinal astrocytes and microglia, systematically summarizing the pathological mechanisms of spinal glial cells involved in CIPN caused by
Long Gu, Song Cao, Yonghuai Feng
wiley +1 more source
Drug Allergy: Delayed Cutaneous Hypersensitivity Reactions to Drugs
Drug allergies, also termed adverse drug reactions (ADRs), are a problem for individuals of all ages, from paediatric to geriatric, and in all medical settings.
Rose L. Hamm
doaj
Modulation of the host Th1 immune response in pigeon protozoal encephalitis caused by Sarcocystis calchasi [PDF]
Pigeon protozoal encephalitis (PPE) is an emerging central-nervous disease of domestic pigeons (Columba livia f. domestica) reported in Germany and the United States.
Gruber, Achim D. +5 more
core +3 more sources
Abstract Objective This study evaluates the diagnostic performance of contrast‐enhanced ultrasound (CEUS) for improving diagnosis of adnexal torsion in women with acute abdominal pain. Methods This was a pilot study of the diagnostic accuracy of CEUS for the detection of adnexal torsion.
Anne‐Laure Fijean +5 more
wiley +1 more source
Review of NSAID Hypersensitivity Reactions Based on Clinical Phenotyping
Nonsteroidal anti-inflammatory drugs (NSAIDs) are widely used for their analgesic, antipyretic, and anti-inflammatory properties. However, they are also associated with a broad spectrum of hypersensitivity reactions, ranging from mild cutaneous ...
Cheong Si Leong +3 more
doaj +1 more source
After activation, Langerhans cells (LC), a distinct subpopulation of epidermis-resident dendritic cells, migrate from skin to lymph nodes where they regulate the magnitude and quality of immune responses initiated by epicutaneously applied antigens ...
Feng, X. +7 more
core +1 more source
Phototherapy and photochemotherapy for polymorphic light eruption desensitisation:a five year case series review from a university teaching hospital [PDF]
Polymorphic light eruption (PLE) is the most common immunological photodermatosis, with a prevalence of 18% in Europe1. The pathogenesis of PLE appears to involve delayed cell mediated hypersensitivity and aberrant Langerhans cell function2,3 ...
Bilsland +7 more
core +2 more sources
Understanding Autistic Young Adults' Perceptions and Experiences of Traumatic and Stressful Events
ABSTRACT Objectives The aim of this study was to explore how young autistic adults experience and respond to stressful life events, and the relationship between autistic characteristics and symptoms of stress associated with these events. Methods Using an exploratory sequential mixed‐methods approach, an online qualitative survey was first administered
Alliyza Lim, Robyn L. Young
wiley +1 more source
The newly developed CRF1-receptor antagonists, NGD 98-2 and NGD 9002, suppress acute stress-induced stimulation of colonic motor function and visceral hypersensitivity in rats. [PDF]
Corticotropin releasing factor receptor 1 (CRF1) is the key receptor that mediates stress-related body responses. However to date there are no CRF1 antagonists that have shown clinical efficacy in stress-related diseases.
Czimmer, József +7 more
core +2 more sources
High‐Frequency Ultrasonographic Characterization of Subcutaneous Glomus Tumors
Color Doppler image reveals intralesional hypervascularity. ABSTRACT Objective To evaluate the clinical manifestations and ultrasonographic characteristics of glomus tumors under the nails and other subcutaneous soft tissues. Methods A retrospective analysis was performed on 45 patients with pathologically confirmed glomus tumors who underwent ...
Mingyu Bai, Nan Wang, Jie Jiang
wiley +1 more source

