Results 171 to 180 of about 630,671 (289)

Sequential anaphylaxis and delayed rituximab-induced serum sickness with skin testing findings: a case report. [PDF]

Allergy Asthma Clin Immunol
Mori S, Okata-Karigane U, Arai M, Takahashi C, Tahara U, Fukushima-Nomura A, Matsuki E, Masaki K, Adachi T.   +8 more
europepmc   +1 more source

Cancer pain: current practice and emerging targets

British Journal of Pharmacology, EarlyView.
Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye, Marcin Chwistek, Zhiting Gong, Vanessa Uzonwanne, Xiaojie Shi, Arpad Szallasi   +5 more
wiley   +1 more source

Neuronal and ion channel mechanisms of noxious heat sensing in mammals: A puzzle of sensory physiology and pharmacology

British Journal of Pharmacology, EarlyView.
Transient receptor potential vanilloid 1 (TRPV1) was the first noxious heat‐sensitive channel discovered. In rodents, its role is robust in the heat response of the cell body of polymodal nociceptors, but surprisingly small in that of the peripheral terminals in the skin.
Gábor Pethő, Peter W. Reeh
wiley   +1 more source

The Tiny Tumor with Disproportionate Pain: Subungual Glomus Tumor of the Thumb Managed with Nail-Sparing Excision: A Case Report. [PDF]

J Orthop Case Rep
Kempulraj P, Veerakumar S, Karthikeyan RKS, Senthil V.   +3 more
europepmc   +1 more source

A Novel Phenotype of Mugwort‐Associated Delayed Gastrointestinal‐Onset Anaphylaxis With Nasal‐Ocular Involvement

Allergy, EarlyView.
Zhouxian Pan, Zhirong Du, Janice A. Layhadi, Bin Yang, Mingle Tian, Juan Liu, Lin Chen, Shengyang Yao, Yan Feng, Lisha Li, Xingyu Zhou, Sainan Bian, Yu Shi, Anqi Li, Lianglu Wang, Kai Guan, Jia Yin, Mohamed H. Shamji   +17 more
wiley   +1 more source

The c‐Src inhibitor eCF506 diminishes opioid tolerance and reduces β‐arrestin2 recruitment

British Journal of Pharmacology, EarlyView.
Morphine activation of μ receptors causes tolerance through c‐Src activation and β‐arrestin2 recruitment. c‐Src inhibition or degradation reduces β‐arrestin2 recruitment, μ receptor endocytosis, while causing receptor upregulation, all likely contributing to reduced morphine tolerance.
Samuel Singleton, Fraser Nunn, Erika Lace, Álvaro Lorente‐Macías, Rachel Toth, Asier Unciti‐Broceta, Tim G. Hales   +6 more
wiley   +1 more source

Reply to Formaldehyde Emissions From 2-Octyl Cyanoacrylate: Quantified Risk for Allergic Contact Dermatitis. [PDF]

Contact Dermatitis
Mofid MM.
europepmc   +1 more source

Algorithms in Allergy: Diagnosis of Hypereosinophilic Syndromes, 2026 Update

Allergy, EarlyView.
Guillaume Lefèvre, Florence Roufosse, Giacomo Emmi, Andreas Reiter, Emmanuel Ledoult, Jean‐Emmanuel Kahn   +5 more
wiley   +1 more source

Rifampin as a novel trigger of drug-induced enterocolitis syndrome. [PDF]

IJTLD Open
Tamborino A, Liccioli G, Tomei L, Chiappini E, Trapani S, Mori F, Galli L, Venturini E.   +7 more
europepmc   +1 more source

Tattoo Inflammation With Uveitis: From Recognition to Definition

Clinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Tattoo inflammation with uveitis (TIU) is increasingly recognised but growing case numbers have revealed substantial heterogeneity. Patients currently classified as TIU appear to include those with overt or evolving systemic sarcoidosis as well as those with isolated, pigment‐associated ocular inflammation.
Anthea Anantharajah, Nicolas Kluger, Anthony J. H. Hall, Michelle Sharp, Jennifer E. Thorne, Lyndell L. Lim   +5 more
wiley   +1 more source