Results 191 to 200 of about 630,671 (289)

A 1% glycopyrronium bromide cream for topical treatment of severe primary axillary hyperhidrosis in adolescents: safety, local tolerability, systemic exposure and efficacy from an open‐label phase II study

open access: yesJDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background and objectives Primary axillary hyperhidrosis (PAHH) results from dysregulation of the autonomic nervous system and typically begins during puberty. Treatment options for adolescents remain limited. This open‐label phase II study evaluated the safety, local tolerability, systemic exposure, and efficacy of 1% GPB cream over 8 weeks in
Rolf‐Markus Szeimies   +8 more
wiley   +1 more source

Using grape seed extract to reduce erosive potential of drinks

open access: yesEuropean Journal of Oral Sciences, EarlyView.
Abstract The aim of this study was to verify whether supplementation of grape seed extract (GSE) to different erosive beverages reduces their erosive potential on dentine in vitro. One‐hundred dentine specimens were randomly assigned to 5 groups (n = 20/group): control‐deionized water, 1%‐citric acid, Red Bull, Coca‐Cola, and Powerade.
Samira Helena Niemeyer   +5 more
wiley   +1 more source

New Insights Into Immunomodulatory Strategies for Drug Hypersensitivity Reactions: An EAACI Task Force Report. [PDF]

open access: yesClin Transl Allergy
Copaescu AM   +13 more
europepmc   +1 more source

A Penicillin Allergy Clinical Decision Rule Performs Differently in Immediate and Delayed Hypersensitivity

open access: yes
Clinical &Experimental Allergy, EarlyView.
Paul Bellmann   +3 more
wiley   +1 more source

Persistent in vitro nociceptor hyperexcitability and axonal retraction produced by repeated paclitaxel doses

open access: yesThe FEBS Journal, EarlyView.
Repeated paclitaxel exposure causes long‐lasting nociceptor hyperexcitability and axonal retraction in adult sensory neurons. Using a long‐term primary nociceptor culture, we show that hyperexcitability is mediated by sequential upregulation of NaV1.8, TRPV1, TRPA1, and TRPM8 channels.
Angela Lamberti   +3 more
wiley   +1 more source

Transgenic selection and underlying mechanisms in apicomplexan parasites

open access: yesThe FEBS Journal, EarlyView.
Transgenic selection markers have driven genetic engineering in apicomplexans, enabling precise, iterative experiments. This review discusses mechanistic details of drug selection markers, strategies for marker recycling, and practical considerations for several clinically relevant parasites.
Swaroop Peddiraju   +2 more
wiley   +1 more source

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