Results 81 to 90 of about 149 (148)
Type I interferon signalling and interferon‐responsive microglia in health and disease
The FEBS Journal, EarlyView.Recent insights reveal that type I interferon (IFN‐I) signalling plays critical roles in the nervous system beyond antiviral defence. Dysregulated IFN‐I activity is increasingly linked to neurological dysfunction and neurodegeneration, with microglia as central mediators. This review explores the broader impact of IFN‐I signalling on the nervous system
Jose P. Lopez‐Atalaya +1 more
wiley +1 more source
Headache characteristics in acromegaly: Only a secondary disorder?
Headache: The Journal of Head and Face Pain, Volume 65, Issue 5, Page 826-834, May 2025.Abstract Objective To investigate the characteristics and nature of headache in a population of patients with acromegaly. Background Headache is frequently described by patients with pituitary adenomas. Although it is mainly considered a secondary disorder, it can persist despite effective therapy for pituitary disease. A proper description of headache
Giada Giuliani +6 more
wiley +1 more source
Headache: The Journal of Head and Face Pain, EarlyView.Abstract Objectives/Background This study was undertaken to evaluate the postmarketing safety of monoclonal antibodies (mAbs) targeting the calcitonin gene‐related peptide pathway used for migraine prophylaxis through pharmacovigilance data analysis by examining suspected adverse events reported in Europe.
Victoria Nikitina +3 more
wiley +1 more source
A programmatic assessment of dolutegravir adverse events and discontinuations in Uganda
HIV Medicine, Volume 26, Issue 4, Page 592-605, April 2025.Abstract Introduction Dolutegravir is now extensively used in sub‐Saharan Africa as a preferred component of antiretroviral therapy (ART). There is a paucity of large studies using routinely collected data from African people living with HIV on dolutegravir‐based regimens to inform HIV programmes.
Eva Agnes Laker Odongpiny +12 more
wiley +1 more source
International Journal of Dermatology, Volume 64, Issue 6, Page 1013-1020, June 2025.ABSTRACT Despite increasing attention regarding skin diseases in individuals with skin of color (SoC), there remains a significant gap in understanding and identifying inflammatory nail disorders in this population. This systematic review aims to synthesize the clinical and onychoscopic features of inflammatory nail disorders in patients with SoC ...
Lea Tordjman +3 more
wiley +1 more source
International Journal of Dermatology, EarlyView.ABSTRACT Background Bullous pemphigoid (BP) is the most common autoimmune blistering disease, with a rising incidence in the elderly. BP is associated with multiple triggering factors, including drug exposure. However, evidence in this respect is limited, and the underlying immune mechanisms remain unknown.
Belen de Nicolas‐Ruanes +17 more
wiley +1 more source
Immunology, EarlyView.Leprosy, a chronic infectious disease caused by Mycobacterium leprae, manifests in a spectrum of clinical forms and severity. This study investigated the percentage of CD8+ T cells and their subpopulations (CD8bright and CD8dim T cells) in leprosy patients stratified by clinical forms, bacterial load, and age.
Yuri Scheidegger de Castro +7 more
wiley +1 more source
Inclusion of Autistic IT Workforce in Action: An Auticon Approach
Information Systems Journal, EarlyView.ABSTRACT This paper examines the IT workforce management practices of auticon, a pioneering international IT consultancy firm from Germany that employs autistic individuals as its core workforce to deliver economically and socially sustainable IT services.
Olga Abramova +3 more
wiley +1 more source
Journal of Esthetic and Restorative Dentistry, EarlyView.ABSTRACT Objective To compare the long‐term microtensile bond strength (μTBS) to coronal dentin using pre‐endodontic dentin sealing (PEDS) and post‐endodontic adhesion (PEA) techniques under various endodontic irrigation protocols. Materials and Methods Ten study groups (n = 10) were established based on the timing of adhesive application (PEDS versus ...
Joana A. Marques +8 more
wiley +1 more source