Results 131 to 140 of about 95,538 (286)
Novel approaches for drug development against chronic primary pain: A systematic review
British Journal of Pharmacology, EarlyView.Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus +5 more
wiley +1 more source
British Journal of Pharmacology, EarlyView.Abstract Chronic pain, marked by nociceptive sensitization and maladaptive neuroplasticity, affects 30% of the global population with escalating socioeconomic burdens. Epidemiological data show a 2‐3‐fold increase in neuropsychiatric co‐morbidities among individuals with chronic pain, where epigenetic dysregulation serves as a key mechanism linking ...
Kai Zhang +18 more
wiley +1 more source
Equine Veterinary Education, EarlyView.Summary The occurrence of Aural Plaques (AP) in horses, attributed to infection with Equus caballus Papillomavirus (EcPV), has become increasingly prevalent in equine breeding populations. Major challenges in managing this condition include genetic susceptibility to the virus, significant variability in individual immune responses among horses and the ...
E. Bastianetto +6 more
wiley +1 more source
Knowledge about occupational latex allergy amongst Thai nurses and student nurses. [PDF]
, 2011 De Vocht, Frank +2 more
core +1 more source
First successful protocol for desensitization to eptinezumab
Headache: The Journal of Head and Face Pain, EarlyView.Abstract Background Eptinezumab is an anti‐calcitonin gene‐related peptide monoclonal antibody used for migraine prevention. During clinical trials, hypersensitivity to eptinezumab was described without a clear underlying mechanism. To determine if the reaction was immunoglobulin E–mediated, the team of Nice University Hospital (Nice, France) performed
Benoit Gerard +8 more
wiley +1 more source
, 1995 Modern biotherapy has been in use for some 30 years. The first types of biotherapy were nonspecific stimulators of the immune response, but advances in genetic engineering are allowing the mass production of pure biological products which are now being ...
Gallucci, Betty Bierut +1 more
core +1 more source
The Complex World of Toothpaste Diversity, Meeting Patient Clinical Needs. An Umbrella Review
International Journal of Dental Hygiene, EarlyView.ABSTRACT Background Amidst numerous recent advancements in toothpaste formulations and active ingredients, some clinicians may believe all toothpastes are similar despite differences in their active ingredients and corresponding clinical application.
Jeanie Suvan, Crystal Marruganti
wiley +1 more source
International Journal of Dental Hygiene, EarlyView.ABSTRACT Background The pursuit of whiter teeth has led to the innovation of various colour enhancement products, including toothpaste formulations containing blue covarine. This systematic review and meta‐analysis assesses their efficacy and safety. Objectives To evaluate the efficacy of blue covarine‐containing toothpaste in colour enhancement and ...
Nina Jelenčiakova +5 more
wiley +1 more source
International Endodontic Journal, EarlyView.ABSTRACT Background New learning methods require higher professor‐to‐student ratios, increased faculty preparation time, continuous professional development for educators, and expanded physical spaces within university settings. Objectives This systematic review aimed to answer the following PICO question: In dental students (P), what is the ...
Ana Arias +4 more
wiley +1 more source
Transillumination‐Aided Infiltration of MIH‐Affected Molars: Evaluation of the Clinical Workflow
International Journal of Paediatric Dentistry, EarlyView.ABSTRACT Background Enamel affected by molar incisor hypomineralisation (MIH) exhibits reduced mechanical properties due to its disorganised prismatic structure, lower mineral density and higher protein content. These alterations increase porosity and susceptibility to posteruptive enamel breakdown.
Omar Marouane +5 more
wiley +1 more source