Results 141 to 150 of about 661,856 (255)

Temporary transfer tattoos and their use in student teaching in dermatology ‐ a monocentric observational study

open access: yesJDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background The teaching of elementary skin lesions and the ABCDE rule are central components of undergraduate medical education in dermatology. This content is typically taught using photographs, moulages, or patient examples. Independent practice under supervision, however, is often difficult to implement in everyday clinical work ...
Conrad Hempel   +3 more
wiley   +1 more source

A Biweekly GLP‐1R Agonist Designed With Drug‐Free Intervals for Enhanced Efficacy, Receptor Homeostasis and Gastrointestinal Tolerability

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aim To develop a next‐generation, longer‐acting, more‐clinical‐benefits agonist to achieve sustained efficacy with improved tolerability. Methods CT130 was designed from semaglutide. Binding affinity was validated via molecular dynamics and cellular assays.
Wei Ding   +4 more
wiley   +1 more source

Bridging the Allergy-Radiology Gap in Radiocontrast Media Hypersensitivity: A Patient-Level Linkage Study on Diagnostic Stewardship and Re-Exposure Outcomes. [PDF]

open access: yesLife (Basel)
Toksoy Şentürk Mİ   +13 more
europepmc   +1 more source

A Novel Phenotype of Mugwort‐Associated Delayed Gastrointestinal‐Onset Anaphylaxis With Nasal‐Ocular Involvement

open access: yes
Allergy, EarlyView.
Zhouxian Pan   +17 more
wiley   +1 more source

Allergen immunotherapy for equine insect bite hypersensitivity: Does it reduce clinical signs?

open access: yesEquine Veterinary Education, EarlyView.
Summary Insect bite hypersensitivity (IBH) is a common, recurrent allergic skin disease of horses. This critically appraised topic evaluated whether therapeutic allergen immunotherapy (AIT) reduces clinical signs in affected horses. Four databases were searched and five therapeutic clinical studies were retained.
R. Cao, E. Maina
wiley   +1 more source

Persistent in vitro nociceptor hyperexcitability and axonal retraction produced by repeated paclitaxel doses

open access: yesThe FEBS Journal, EarlyView.
Repeated paclitaxel exposure causes long‐lasting nociceptor hyperexcitability and axonal retraction in adult sensory neurons. Using a long‐term primary nociceptor culture, we show that hyperexcitability is mediated by sequential upregulation of NaV1.8, TRPV1, TRPA1, and TRPM8 channels.
Angela Lamberti   +3 more
wiley   +1 more source

Transgenic selection and underlying mechanisms in apicomplexan parasites

open access: yesThe FEBS Journal, EarlyView.
Transgenic selection markers have driven genetic engineering in apicomplexans, enabling precise, iterative experiments. This review discusses mechanistic details of drug selection markers, strategies for marker recycling, and practical considerations for several clinically relevant parasites.
Swaroop Peddiraju   +2 more
wiley   +1 more source

Clinical phenotypes, endotypes, and biomarker profiles of immediate rituximab hypersensitivity reactions: a prospective pharmacovigilance study. [PDF]

open access: yesFront Allergy
Yotinnoratham N   +14 more
europepmc   +1 more source

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