Results 141 to 150 of about 94,721 (312)

Stimulus specificity of the generation of leukotrienes by dog mastocytoma cells. [PDF]

open access: yes, 1983
Isolated dog mastocytoma cells sensitized with dog anti-ragweed IgE and challenged with ragweed antigen or incubated with ionophore A23187 or the carboxy-terminal dodecapeptide of platelet factor 4, PF4(59-70), release histamine and concurrently generate
Goetzl, EJ, Gold, WM, Phillips, MJ
core  

Psilocybin as a novel treatment for chronic pain

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Psychedelic drugs are under active consideration for clinical use and have generated significant interest for their potential as anti‐nociceptive treatments for chronic pain, and for addressing conditions like depression, frequently co‐morbid with pain.
Tate Askey   +3 more
wiley   +1 more source

Psychedelics as pharmacotherapeutics for substance use disorders: A scoping review on clinical trials and perspectives on underlying neurobiology

open access: yesBritish Journal of Pharmacology, EarlyView.
Theorized mechanism of dopamine homeostasis restoration in the nucleus accumbens core induced by a psychedelic intervention. Abstract Psychedelics have garnered great attention in recent years as treatments for major depressive disorder (MDD) and treatment‐resistant depression because of their ability to alter consciousness and afflicted cognitive ...
Lucas Wittenkeller   +3 more
wiley   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus   +5 more
wiley   +1 more source

Staphylococcus aureus Sb‐1 Bacteriophage Alters Frequency and Subset Distribution of Human Innate Lymphoid Cells

open access: yes
Allergy, EarlyView.
Ramazan Rozumbetov   +14 more
wiley   +1 more source

Diverging in Vivo Immune Response Patterns After Oral Food Challenge in Peanut Allergic Adults

open access: yesClinical &Experimental Allergy, EarlyView.
After the oral food challenge, peanut (PN)‐allergic adults were monitored over 4 weeks, which revealed diverging immune response patterns, with strong responders (SR) exhibiting heightened Ara h 2+ B cell expansion, PN sIgE induction and increasing PN‐specific Tconv. Weak responders (WR) had more activated PN‐specific Tregs.
Florent Fauchère   +7 more
wiley   +1 more source

immediate-type hypersensitivity

open access: yes
Citation: 'immediate-type hypersensitivity' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.13255 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual ...
openaire   +1 more source

Quality and Consistency of Penicillin Allergy Delabelling Guidelines: A Systematic Review

open access: yesClinical &Experimental Allergy, EarlyView.
Eighteen penicillin allergy delabelling guidelines from 12 countries were reviewed. There is consensus for staged risk‐based testing, with emerging support for direct oral challenge in low‐risk patients and expanded non‐specialist roles. Overall guideline quality was low, with major gaps in methodological rigour, stakeholder involvement, and ...
Jessie He   +8 more
wiley   +1 more source

Temporalities of Trauma: An Exploration of the Role of Socio‐Temporal Rhythms in Foster Carer Experiences of Vicarious Trauma

open access: yesChild &Family Social Work, EarlyView.
ABSTRACT Foster carers raise children whose trauma backgrounds likely result in behaviours that are not simply challenging, but which can also result in vicarious trauma for foster carers. While a growing body of research has explored vicarious trauma among foster carers, to date research has not explored how temporal shifts produced by raising foster ...
Sam Arthurson   +2 more
wiley   +1 more source

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