Results 111 to 120 of about 521,930 (421)
Advanced Science, EarlyView.The therapeutic potential of ApoVs derived from stem cells from human exfoliated deciduous teeth (SHED‐ApoVs) in the treatment of CD8+ T cell‐mediated hypersensitivity reactions is noteworthy. SHED‐ApoVs are capable of fusing with the plasma membrane of CD8+ T cells, which subsequently triggers a series of events characterized by calcium overload ...
Anqi Liu +13 more
wiley +1 more source
Hypersensitivity to perturbation: An information-theoretical characterization of classical and quantum chaos [PDF]
Quantum Communication, Computing, and Measurement, edited by O.
Hirota, A. S. Holevo, and C. M. Caves, (Plenum Press, New York, 1997), pp.
317-330, 1997 Hypersensitivity to perturbation is a criterion for chaos based on the question of how much information about a perturbing environment is needed to keep the entropy of a Hamiltonian system from increasing. In this paper we give a brief overview of our work on hypersensitivity to perturbation in classical and quantum systems.
arxiv
Journal of Investigative Dermatology, 1989 Hypersensitivity angiitis is a disease in which patients present with palpable purpura dominant on the lower legs. As lesions evolve they become confluent, and sometimes hemorrhagic and ulcerate. Other organ systems may be involved, particularly the joints, gastrointestinal tract, and kidneys. Current evidence supports an immune complex pathogenesis in
openaire +2 more sources
Advanced Science, EarlyView.Staphylococcus aureus (S. aureus) infection induces persistent pain via toxins, leading to CGRP release from TRPV1+ nociceptive nerves. CGRP inhibits chemotactic factor release from CX3CR1+ synovial lining macrophages and suppresses their bactericidal activity. This study highlights neuroimmune interactions in chronic septic arthritis and suggests CGRP
Xinyu Fang +19 more
wiley +1 more source
Mechanisms of Hypersensitivity [PDF]
, 2013 Allergic reactions to drugs are not always the result of the drug’s protein-binding capacity, biotransformation, or degradation. Mediator release may occur via cross-linking of cell-bound IgE by di-(multi-) valent free drug. Physiological and pharmacological effects of histamine are mediated through four receptors, H(1), H(2), H(3), and H(4.) The H(3 ...
Brian A. Baldo, Nghia H. Pham
openaire +2 more sources
Nanotherapy for Neural Retinal Regeneration
Advanced Science, EarlyView.Nanotechnology enhances ophthalmic treatments by improving drug delivery and regenerating ocular tissues, combating vision loss from retinal diseases through innovative nano‐systems. This review outlines ocular anatomy, pathology, immune microenvironment, and barriers, detailing nanocarrier characteristics, classification, and preparation methods, and ...
Chuyao Yu +11 more
wiley +1 more source
Stokes' Drift and Hypersensitive Response with Dichotomous Markov Noise [PDF]
Fluctuations and Noise Letters 5, L397-L415 (2005)., 2005 Stochastic Stokes' drift and hypersensitive transport driven by dichotomous noise are theoretically investigated. Explicit mathematical expressions for the asymptotic probability density and drift velocity are derived including the situation in which particles cross unstable fixed points. The results are confirmed by numerical simulations.
arxiv
The alternatively spliced fibronectin CS1 isoform regulates IL-17A levels and mechanical allodynia after peripheral nerve injury. [PDF]
, 2015 BackgroundMechanical pain hypersensitivity associated with physical trauma to peripheral nerve depends on T-helper (Th) cells expressing the algesic cytokine, interleukin (IL)-17A.
Angert, Mila +9 more
core +3 more sources
Reflux Hypersensitivity: A New Functional Esophageal Disorder
Journal of Neurogastroenterology and Motility, 2017 Reflux hypersensitivity, recently introduced by Rome IV as a new functional esophageal disorder, is currently considered as the presence of typical heartburn symptoms in patients with normal upper endoscopy and esophageal biopsies, normal esophageal pH ...
Takahisa Yamasaki, R. Fass
semanticscholar +1 more source
Large‐Scale Plasma Proteomics to Profile Pathways and Prognosis of Chronic Pain
Advanced Science, EarlyView.This study delineates both common and site‐specific proteins linked to various chronic pain conditions, elucidating their implications across molecular pathways and health status. These findings, particularly those proteins with genetic causal links to pain or predictive capabilities, have the potential to significantly benefit both research and ...
Ze‐Yu Li +17 more
wiley +1 more source