Results 91 to 100 of about 358,537 (259)
Genetic screening to prevent abacavir hypersensitivity reaction: Are we there yet? [PDF]
, 2006 Editorial ...
Phillips, E.J.
core
Advanced Science, EarlyView.Astrocyte‐specific SHP1 deletion disrupts astrocyte–vascular interactions and compromises BBB integrity while enhancing STAT1‐dependent CXCL10 expression. These changes synergistically promote peripheral CD4+ and CD8+ T‐cell infiltration into the SDH. The infiltrating T cells secrete IFN‐γ, which in turn activates microglia.
Lan‐Xing Yi +7 more
wiley +1 more source
Progesterone hypersensitivity: A challenge for luteal support
Journal of Human Reproductive Sciences, 2018 Progesterone hypersensitivity is a rare phenomenon which can occur after both endogenous and exogenous exposures. We present a case of hypersensitivity to various forms and routes of exogenous progesterone.
Astha Gupta +2 more
doaj +1 more source
VlPAG/DRN Microglia Drive Neuropathic Pain‐Induced Depression via a Defined Neuroimmune Axis
Advanced Science, EarlyView.Peripheral nerve injury (SNI) induces neuropathic pain, activates midbrain microglia, and triggers an NLRP3–IL‐1β–dependent inflammatory cascade. IL‐1β signals through IL‐1R1 on vlPAG/DRN VGLUT2+ neurons (vlPAG/DRNGlu), inducing hyperexcitability and driving the vlPAG/DRNGlu→BNSTGABA circuit to produce the affective component of neuropathic pain ...
Jing Yang +7 more
wiley +1 more source
Psoriasis: Targets and TherapyHsiu-Ting Chien,1 Chien-Yu Tseng,1 Chun-Wei Lu,2,3 Wen-Hung Chung,2,3 Fang-Ju Lin1,4,5 1Graduate Institute of Clinical Pharmacy, College of Medicine, National Taiwan University, Taipei, Taiwan; 2Department of Dermatology, Drug Hypersensitivity Clinical ...
Chien HT +4 more
doaj
In-office treatment for dentin hypersensitivity: a systematic review and network meta-analysis
, 2014 Aim Dentin hypersensitivity, caused by the exposure and patency of dentinal tubules, can affect patients' quality of life. The aim of this study was to undertake a systematic review and a network meta-analysis, comparing the effectiveness in resolving ...
Lin, Po-Yen;Cheng, Ya-Wen;Chu, Chia-Yi;Chien, Kuo-Liong;Lin, Chun-Pin;Tu, Yu-Kang +1 more
core +1 more source
Advanced Science, EarlyView.Tissue incision induces CXCL5 release, which activates neuronal CXCR2 on incision‐innervating sensory neurons. Neuronal CXCR2 couples with TRPA1 to drive mechanical pain and engages p38 MAPK signaling to upregulate TRPV1 and promote heat pain. Targeted Cxcr2 knockdown relieves incisional pain while preserving CXCR2‐dependent neutrophil responses ...
Yushuang Pan +10 more
wiley +1 more source
Revista Electrónica Dr. Zoilo E. Marinello Vidaurreta, 2021 Background: the correct diagnosis on what the allergens that sensitize the patient are makes it possible to establish an adequate management of the disease, avoiding the contact of patients with these allergens and establishing a more precise ...
Lourdes Leonor Bermudez-Cordoví +3 more
doaj
Advanced Science, EarlyView.This article aims to elucidate the biological mechanisms of bone repair and the evolution of material design, highlighting key cellular and molecular processes. It further proposes strategies and prospects for programmable bio‐interactive materials, which enable precisely guided bone tissue regeneration by dynamically regulating cell behavior and the ...
Qingrui Fan +6 more
wiley +1 more source
Journal of Asthma and Allergy, 2020 Lubna Khreesha,1 Mohammad Ghunaim,1 Mohamad-Amin Ramzown,1 Mohammad Alkhoujah,2 Mohamed Tawalbeh,1 Montaha Al-Iede,3 Tareq Kanaan,4 Mustafa Alrabayah,5 Suhaib Eid1 1Otolaryngology, Department of Special Surgeries, Faculty of Medicine, The University of ...
Khreesha L +8 more
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