Results 141 to 150 of about 648,308 (386)

Overcoming PEG Antigenicity: Statistical PEG Isomers Reduce Antibody Binding

Advanced Science, EarlyView.
Conventional poly(ethylene glycol) (PEG) is commonly applied in biomedicine, but is now known to induce antibody formation. Here, it is shown that the development of “randomized PEG” (rPEG) featuring glycidyl methyl ether (GME) comonomers decreased antibody binding.
Mareike Deuker, Dominik Schulz, Kaloian Koynov, Svenja Morsbach, Holger Frey, Katharina Landfester   +5 more
wiley   +1 more source

What makes women with food hypersensitivity do self-management work? [PDF]

, 2019
Monika Dybdahl Jakobsen, Aud Obstfelder, Tonje Braaten, Birgit Abelsen   +3 more
openalex   +1 more source

Self‐Assembled Myricetin‐Arginine Conjugate Nanozymes for Targeted Suppression of Joint Inflammation and Osteoclastogenesis in Rheumatoid Arthritis

Advanced Science, EarlyView.
Carrier‐free myricetin‐arginine conjugate nanozymes (MANZs) have been fabricated through a Mannich reaction and spontaneous self‐assembly. MANZs selectively accumulate in inflamed joints by targeting M1 macrophages via CAT2‐mediated uptake. The nanozymes can effectively modulate macrophage polarization, suppress osteoclast differentiation, and mitigate
Jiachang Hong, Penghao Ji, Jinxi An, Junchao Huang, Ziheng Bu, Xudong Zhang, Wei Liu, Tingyu Wu, Sen Wang, Wei Zhu, Yuhui Li, Jixian Wan, Sudan Xu, Minfeng Huo, Peng Wu   +14 more
wiley   +1 more source

Mechanisms conferring sensitivity to low dose radiation exposure and consideration of potentially sensitivie individuals [PDF]

, 2009
No description ...
Jeggo, Penny
core  

Wearable Thermoelectric Generators for In Vivo Modulation of Insulin Release

Advanced Energy Materials, EarlyView.
This work presents a wearable, self‐powered thermoelectric system (IGNITE) that sustainably harvests body heat to electrically stimulate engineered human cells for insulin release. Operating autonomously without batteries, IGNITE achieves glycemic control in diabetic mice, demonstrating a significant advance in bioelectronic medicine and setting the ...
Debasis Maity, Jinbo Huang, Martin Fussenegger   +2 more
wiley   +1 more source

FURTHER OBJECTIVE STUDIES IN CHILDREN WITH HYPERSENSITIVITY TO FOODS [PDF]

, 1977
S. Allan Bock, Charles D. May
openalex   +1 more source

Treg Cells Modulate Neuroinflammation and Behavioral Deficits in Autism: Evidence From MR‐Based Genetic Analyses and Experimental Models

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Autism spectrum disorder (ASD) is a neurodevelopmental condition that is increasingly linked to immune dysfunction and neuroinflammation. Regulatory T cells (Tregs), which are crucial in maintaining immune homeostasis, have been implicated in the pathogenesis of ASD.
Zuqing Nie, Xinyi Xu, Junhao Chen, Huiling Chen, Meng Li, Yang Zhang, Zhiwei Li, Chen Shen, Jie Wen, Xia Cao   +9 more
wiley   +1 more source

Contemporary management of pain in cirrhosis: Toward precision therapy for pain

Hepatology, EarlyView., 2022
Abstract Chronic pain is highly prevalent in patients with cirrhosis and is associated with poor health‐related quality of life and poor functional status. However, there is limited guidance on appropriate pain management in this population, and pharmacologic treatment can be harmful, leading to adverse outcomes, such as gastrointestinal bleeding ...
Alexis Holman, Neehar Parikh, Dan J. Clauw, David A. Williams, Elliot B. Tapper   +4 more
wiley   +1 more source

Local Specific IgE Levels Can Predict and Monitor the Therapeutic Response to Subcutaneous Immunotherapy With House Dust Mite

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Identifying predictive and monitoring biomarkers for allergen immunotherapy response is crucial for enhancing clinical efficacy. This study aims to investigate the systemic and local levels of immunoglobulins and identify potential biomarkers in house dust mite (HDM) allergic rhinitis (AR) patients who are undergoing subcutaneous ...
Xu Xu, Jingyun Li, Xu Zhang, Yu Song, Lin Xi, Luo Zhang, Yuan Zhang   +6 more
wiley   +1 more source

The Role of Bacterial Toxins and Environmental Factors in the Development of Food Allergies

Allergies
Food allergies (FAs) represent a significant and growing global health issue, with increasing prevalence across different age groups. This review provides a comprehensive analysis of the epidemiology, mechanisms, and risk factors involved in FA ...
Ahsanullah Unar, Muqaddas Qureshi, Hassan Imran Afridi, Shafkatullah Wassan   +3 more
doaj   +1 more source